Analysis of the trans-Cinnamic Acid Content in Cinnamomum spp. and Commercial Cinnamon Powder Using HPLC

DOI: 10.4236/jacen.2015.44011   PDF   HTML   XML   3,605 Downloads   4,590 Views   Citations

Abstract

The present study aimed to quantify the content of trans-cinnamic acid (CA) in Cinnamomum japonicum, C. loureirii, and C. camphora and the commercial application of CA using high performance liquid chromatography (HPLC). A C18 column was used, with water/methanol as the mobile phase gradient. The highest content of CA was observed in the bark of C. loureirii (16.97 mg/g) and cinnamon powder A (47.60 mg/g). The lowest content of CA was observed in leaf and heartwood of C. japonicum (0.10 and 0.10 mg/g, respectively) and cinnamon powder C (22.87 mg/g). This result could be utilized as a guideline for the analysis of the commercial applications of Cinnamomum.

Share and Cite:

Lee, J. , Lee, D. , Park, J. , Chae, S. and Lee, S. (2015) Analysis of the trans-Cinnamic Acid Content in Cinnamomum spp. and Commercial Cinnamon Powder Using HPLC. Journal of Agricultural Chemistry and Environment, 4, 102-108. doi: 10.4236/jacen.2015.44011.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] Lee, S.C., Lee, S.C., Lin, M.Y. and Ho, K.Y. (2010) Genetic Identification of Cinnamomum Species Based on Partial Internal Transcribed Spacer 2 of Ribosomal DNA. Journal of Food and Drug Analysis, 18, 225-231.
[2] Al-Mamun, R., Hamid, A., Islam, M.K., Chowdhury, J.A. and Zafrul Azam, A.T.M. (2011) Lipid Lowering Activity and Free Radical Scavenging Effect of Cinnamomum tamala (Fam: Lauraceae). International Journal of Natural Sciences, 1, 93-96.
[3] Joshi, S.C., Verma, A.R. and Mathela, C.S. (2010) Antioxidant and Antibacterial Activities of the Leaf Essential Oils of Himalayan Lauraceae Species. Food and Chemical Toxicology, 48, 37-40.
http://dx.doi.org/10.1016/j.fct.2009.09.011
[4] Palazzo, M.C., Agius, B.R., Wright, B.S., Haber, W.A., Moriarity, D.M. and Setzer, W.N. (2009) Chemical Compositions and Cytotoxicity Activities of Leaf Essential Oils of Four Lauraceae Tree Species from Monteverde, Costa Rica. Records of Natural Products, 3, 32-37.
[5] Sangal, A. (2011) Role of Cinnamon as a Beneficial Antidiabetic Food Adjunct: A Review. Advances in Applied Science Research, 2, 440-450.
[6] Li, R., Wang, Y. and Jiang, Z.T. (2010) Chemical Constituents of the Essential Oils of Cinnamomum loureirii Nees. from China Obtained by Hydrodistillation and Microwave-Assisted Hydrodistillation. Journal of Essential Oil Research, 22, 129-131. http://dx.doi.org/10.1080/10412905.2010.9700281
[7] Lin, C.C., Yang, C.H., Wu, P.S., Kwan, C.C. and Chen, Y.S. (2011) Antimicrobial, Anti-Tyrosinase and Antioxidant Activities of Aqueous Aromatic Extracts from Forty-Eight Selected Herbs. Journal of Medicinal Plants Research, 5, 6203-6209.
[8] Chen, H.P., Yang, K., You, C.H., Lei, N., Sun, R.Q., Geng, Z.F., Ma, P., Cai, Q., Du, S.S. and Deng, Z.W. (2014) Chemical Constituents and Insecticidal Activities of the Essential Oil of Cinnamonmum camphora Leaves against Lasioderma serricorne. Journal of Chemistry, 2014, 1-5.
[9] Shareef, A.A. (2011) Evaluation of Antibacterial of Essential Oils of Cinnamomum sp. and Boswellia sp. Journal of Basrah Researches, 37, 60-71.
[10] Li, Y.Q., Kong, D.X. and Wu, H. (2013) Analysis and Evaluation of Essential Oil Components of Cinnamon Barks Using GC-MS and FTIR Spectroscopy. Industrial Crops and Products, 41, 269-278.
http://dx.doi.org/10.1016/j.indcrop.2012.04.056
[11] Pina-Pérez, M.C., Martínez-López, A. and Rodrigo, D. (2012) Cinnamon Antimicrobial Effect against Salmonella typhimurium Cells Treated by Pulsed Electric Fields (PEF) in Pasteurized Skim Milk Beverage. Food Research International, 48, 777-783. http://dx.doi.org/10.1016/j.foodres.2012.06.027
[12] Couturier, K., Qin, B., Batandier, C., Awada, M., Hininger-Favier, I., Canini, F., Leverve, X., Roussel, A.M. and Anderson, R.A. (2011) Cinnamon Increase Liver Glycogen in an Animal Model of Insulin Resistance. Metabolism, 11, 1590-1597. http://dx.doi.org/10.1016/j.metabol.2011.03.016
[13] Kwon, H.K., Jeon, W.K., Hwang, J.S., Lee, C.G., So, J.S., Park, J.A., Ko, B.S. and Im, S.H. (2009) Cinnamon Extract Suppresses Tumor Progression by Modulating Angiogenesis and the Effector Function of CD8+ T Cells. Cancer Letters, 278, 174-182. http://dx.doi.org/10.1016/j.canlet.2009.01.015
[14] Kim, D.S., Na, H., Song, J.H., Kwack, Y., Kim, S.K. and Chun, C.H. (2012) Antimicrobial Activity of Thinned Strawberry Fruits at Different Maturation Stages. Korean Journal of Horticultural Science and Technology, 30, 769-775. http://dx.doi.org/10.7235/hort.2012.12199
[15] Bock, C.H., Shapiro-Ilan, D.I., Wedge, D.E. and Cantrell, C.L. (2014) Identification of the Antifungal Compound, Trans-Cinnamic Acid, Produced by Photorhabdus luminescens, a Potential Biopesticide against Pecan Scab. Journal of Pest Science, 87, 155-162. http://dx.doi.org/10.1007/s10340-013-0519-5
[16] Mahajan, R., Singh, P. and Bajaj, K.L. (1992) Nematicidal Activity of Some Phenolic Compounds against Meloidogyne incognita. Nematologia Mediterranea, 20, 217-219.
[17] Kuk, J.H., Ma, S.J. and Park, K.H. (1997) Isolation and Characterization of Cinnamic Acid with Antimicrobial Activity from Needle of Pinus densiflora. Korean Journal of Food Science and Technology, 29, 823-826.
[18] Lukmanul Hakkim, F., Miura, M., Matsuda, N., Alharassi, A.S., Guillemin, G., Yamauchi, M., Arivazhagan, G. and Song, H. (2014) An in Vitro Evidence for Caffeic Acid, Rosmarinic Acid and Trans Cinnamic Acid as a Skin Protectant Agent against γ-Radiation. International Journal of Low Radiation, 9, 305-316.
http://dx.doi.org/10.1504/IJLR.2014.063414
[19] Rahman, A.U. (2014) Studies in Natural Products Chemistry. Vol. 42, Elsevier, Oxford, 276.
[20] Ding, Y., Wu, E.Q., Liang, C., Chen, J., Tran, M.N., Hong, C.H., Jang, Y., Park, K.L., Bae, K.H., Kim, Y.H. and Kang, J.S. (2011) Discrimination of Cinnamon Bark and Cinnamon Twig Samples Sourced from Various Countries Using HPLC-Based Fingerprint Analysis. Food Chemistry, 127, 755-760.
http://dx.doi.org/10.1016/j.foodchem.2011.01.011
[21] Krieger, S., Hayen, H. and Schmitz, O.J. (2013) Quantification of Coumarin in Cinnamon and Woodruff Beverages Using DIP-APCI-MS and LC-MS. Analytical and Bioanalytical Chemistry, 405, 8337-8345.
http://dx.doi.org/10.1007/s00216-013-7238-x
[22] Carrasco Pancorbo, A., Cruces-Blanco, C., Segura Carrentero, A. and Fernández Gutiérrez, A. (2004) Sensitive Determination of Phenolic Acids in Extra-Virgin Olive Oil by Capillary Zone Electrophoresis. Journal of Agricultural and Food Chemistry, 52, 6687-6693. http://dx.doi.org/10.1021/jf0497399
[23] Croci, A.N., Cioroiu, B., Lazar, D., Corciova, A., Ivanescu, B. and Lazar, M.I. (2009) HPLC Evaluation of Phenolic and Polyphenolic Acids from Propolis. Farmacia, 57, 52-57.
[24] Chalchat, J.C. and Valade, I. (2000) Chemical Composition of Leaf Oils of Cinnamomum from Madagascar: C. zeylanicum. Blume, C. camphora L., C. frangas Baillon and C. angustifolium. Journal of Essential Oil Research, 12, 537- 540. http://dx.doi.org/10.1080/10412905.2000.9712153
[25] Ballin, N.Z. and Sorensen, A.T. (2014) Coumarin Content in Cinnamon Containing Food Products on the Danish Market. Food Control, 38, 198-203. http://dx.doi.org/10.1016/j.foodcont.2013.10.014
[26] Lim, S.J., Lee, J.H., Kim, H.J., Choi, G.H., Cho, N.J. and Park, B.J. (2014) Quantitative Analysis of Cinnamaldehyde, Cinnamylalcohol and Salicylaldehyde in Commercial Biopesticides Containing Cinnamon Extract Using Gas Chromatography—Flame Ionization Detector. Korean Journal of Environmental Agriculture, 33, 213-219. http://dx.doi.org/10.5338/KJEA.2014.33.3.213
[27] Adisakwattana, S., Sookkongwaree, K., Roengsumran, S., Petsom, A., Ngamrojnavanich, N., Chavasiri, W., Deesamer, S. and Yibchok-anun, S. (2004) Structure-Activity Relationships of Trans-Cinnamic Acid Derivatives on Alpha-Glucosidase Inhibition. Bioorganic and Medicinal Chemistry Letters, 14, 2893-2896. http://dx.doi.org/10.1016/j.bmcl.2004.03.037
[28] Van Overbeek, J., Blondeau, J. and Horne, V. (1951) Trans-Cinnamic Acid as an Anti-Auxtin. American Journal of Botany, 38, 589-595. http://dx.doi.org/10.2307/2437768

  
comments powered by Disqus

Copyright © 2020 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.