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A Case Report of Pediatric Epstein Barr Virus (EBV) Related Cholestasis from Al-Adan Hospital, Kuwait

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DOI: 10.4236/ojped.2015.51005    3,217 Downloads   3,895 Views   Citations

ABSTRACT

Infectious mononucleosis is an acute illness due to Epstein Barr virus infection, which occurs commonly in young adults. Liver involvement in acute EBV infection occurs in up to 95% of patients between the 6th and 15th day of illness and is usually mild [1]. Here we report on a 7-year-old girl treated by Gastroenterology, Hepatology, and Nutrition Unit of Al-Adan Hospital pediatric Department, presented with prolonged fever, lymphadenopathy, generalized edema, hyperbilurubi- nemia and elevated liver enzymes secondary to EBV infection. This case represents a rare presentation of common viral infection in pediatric population.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Al-Refaee, F. , Al-Enezi, S. , Hoque, E. and Albadrawi, A. (2015) A Case Report of Pediatric Epstein Barr Virus (EBV) Related Cholestasis from Al-Adan Hospital, Kuwait. Open Journal of Pediatrics, 5, 23-26. doi: 10.4236/ojped.2015.51005.

References

[1] Rapp Jr., C.E. and Hewetson, J.F. (1978) Infectious Mononucleosis and the Epstein-Barr Virus. American Journal of Diseases of Children, 132, 78-86.
[2] Barlow, G., Kilding, R. and Green, S. (2000) Epstein-Barr Virus Mimicking Extra-Hepatic Biliary Obstruction. Journal of the Royal Society of Medicine, 93, 316-318.
[3] Jenson, H.B. (2000) Acute Complications of Epstein-Barr Virus Infectious Mononucleosis. Current Opinion in Pediatrics, 12, 263-268. http://dx.doi.org/10.1097/00008480-200006000-00016
[4] Hoagland, R.J. (1955) The Transmission of Infectious Mononucleosis. The American Journal of the Medical Sciences, 3, 229-262.
[5] Anagnostopoulos, I., Hummel, M., Kreschel, C. and Stein, H. (1995) Morphology, Immunophenotype, and Distribution of Latently and/or Productively Epstein-Barr Virus-Infected Cells in Acute Infectious Mononucleosis: Implications for the Interindividual Infection Route of Epstein-Barr Virus. Blood, 85, 744-750.
[6] Aronson, M.D. and Auwaerter, P.G., Hirsch, M.S., Kaplan, S.L. and Mitty, J., Eds. Infectious Mononucleosis in Adults and Adolescents. UpToDate.
[7] (1972) General Features of Infectious Mononucleosis (Roundtable Discussion). In: Glade, P.R., Ed., Infectious Mononucleosis: Proceedings of Symposium, New York, 7 April 1972, Philadelphia, JB Lippincott, 1-18.
[8] Shaukat, A., Tsai, H.T., Rutherford, R. and Anania, F.A. (2005) Epstein-Barr Virus Induced Hepatitis: An Important Cause of Cholestasis. Hepatology Research, 33, 24-26.
http://dx.doi.org/10.1016/j.hepres.2005.06.005
[9] Juttner, H.U., Ralls, P.W., Quinn, M.F., et al. (1982) Thickening of the Gall-Bladder Wall in Acute Hepatitis: Ultrasound Demonstration. Radiology, 142, 465-466. http://dx.doi.org/10.1148/radiology.142.2.7054838
[10] Patel, S., Zuckerman, M. and Smith, M. (2003) Real-Time Quantitative PCR of Epstein-Barr Virus BZLF1 DNA Using the LightCycler. Journal of Virological Methods, 109, 227-233.
http://dx.doi.org/10.1016/S0166-0934(03)00076-4
[11] Yamada, K. and Yamada, H. (2001) Gallbladder Wall Thickening in Mononucleosis Syndromes. Journal of Clinical Ultrasound, 29, 322-325. http://dx.doi.org/10.1002/jcu.1042

  
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