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Current Treatment of DCIS

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DOI: 10.4236/jct.2014.52022    3,746 Downloads   5,118 Views  

ABSTRACT

Abstract: Ductal carcinoma in-situ DCIS is a heterogeneous entity in breast neoplasm with unpredictable biological behavior. This poses challenge in the management of DCIS. Various trials on DCIS have shown good outcome with integral treatment of adequate surgery, radiotherapy and hormonal therapy. Identification of subgroup of DCIS for radiotherapy and hormonal therapy could improve recurrence rate, contralateral tumours incidence and perhaps overall survival. Various risk score calculations could help to direct radiotherapy and hormonal treatment verses surgery alone and to avoid over treatment. Oncotype DX assay could be a new way of risk calculation to direct types of DCIS treatment. The recent increased use of MRI could increase the detection of DCIS and a more accurate extent of disease estimation. This article is a summary of major literatures and major trials result for DCIS.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

C. Choy and K. Mokbel, "Current Treatment of DCIS," Journal of Cancer Therapy, Vol. 5 No. 2, 2014, pp. 179-181. doi: 10.4236/jct.2014.52022.

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