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Cyclic Bis(3'-5')diadenylic Acid (c-di-AMP) Analogs Promote the Activities of Photosynthesis and Respiration of Chlamydomonas reinhardtii

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DOI: 10.4236/ajps.2014.51004    3,147 Downloads   4,675 Views   Citations


Physiological changes in the photosynthesis, respiration and cell division of Chlamydomonas reinhardtii, a freshwater green alga, in response to adenine nucleotides were investigated. In advance of this investigation, two adenine nucleotides, di(2'-O-methyl)-cyclic bis(3'-5')diadenylic acid (1) and its N-benzoyl-protected analog 2 were synthesized from the commercially available adenosine phosphoramidite. The respective analogs significantly promoted the cell division (cell number) of C. reinhardtii strains 137c mt+ and BR mt+. Moreover, they significantly enhanced the O2 evolution (photosynthesis) and O2 uptake (respiration) of both strains. c-di-AMP analogs seem to play an effective role as a physiological activator in planta.

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T. Tezuka, H. Shirouzu, K. Ishida, N. Suzuki, T. Matsuo, K. Oyama, S. Aoki and M. Tsukamoto, "Cyclic Bis(3'-5')diadenylic Acid (c-di-AMP) Analogs Promote the Activities of Photosynthesis and Respiration of Chlamydomonas reinhardtii," American Journal of Plant Sciences, Vol. 5 No. 1, 2014, pp. 24-28. doi: 10.4236/ajps.2014.51004.


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