CT, MRI, and 18F-FDG PET-CT Findings of Pulmonary Benign Metastasizing Leiomyoma: A Case Report

Abstract

Here we report imaging studies of a patient with pulmonary benign metastasizing leiomyoma (BML). A 44-year-old woman who underwent a hysterectomy for uterine cellular leiomyoma presented with abnormal shadows on a chest X-ray. Chest computed tomography (CT) revealed multiple well-defined nodules in both lungs. Chest magnetic resonance imaging (MRI) indicated these nodules as T1-low/T2-high intensity lesions. Contrast-enhanced MRI indicated these nodules as well-enhanced lesions, while 18F-fluorodeoxyglucose positron emission tomography-CT revealed no abnormal accumulation in these nodules. Bilateral lung wedge resections were performed for the largest 2 lesions to confirm the diagnosis, and both nodules were histologically diagnosed as BML.

Share and Cite:

R. Okita, K. Yasuda, Y. Nojima, A. Maeda, T. Yukawa, S. Saisho, K. Shimizu, T. Akiyama, Y. Miyagi, T. Oda and M. Nakata, "CT, MRI, and 18F-FDG PET-CT Findings of Pulmonary Benign Metastasizing Leiomyoma: A Case Report," Open Journal of Thoracic Surgery, Vol. 3 No. 4, 2013, pp. 127-129. doi: 10.4236/ojts.2013.34026.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] P. E. Steiner, “Metastasizing Fibroleiomyoma of the Uterus: Report of a Case and Review of the Literature,” American Journal of Pathology, Vol. 15, No. 1, 1939, pp. 89-110.
[2] J. A. Rivera, S. Christopolus, D. Small and M. Trifiro, “Hormonal Manipulation of Benign Metastasizing Leiomyomas: Report of Two Cases and Review of the Literature,” The Journal of Clinical Endocrinology & Metabolism, Vol. 89, No. 7, 2004, pp. 3183-3188. http://dx.doi.org/10.1210/jc.2003-032021
[3] K. Hoetzenecker, H. J. Ankersmit, C. Aigner, M. Lichtenauer, S. Kreuzer, S. Hacker, W. Hoetzenecker, G. Lang and W. Klepetko, “Consequences of a Wait-and-See Strategy for Benign Metastasizing Leiomyomatosis of the Lung,” The Annals of Thoracic Surgery, Vol. 87, No. 2, 2009, pp. 613-614. http://dx.doi.org/10.1016/j.athoracsur.2008.06.052
[4] S. Abramson, R. C. Glikeson, J. D. Goldstein, P. K. Woodard, R. Eisenberg and N. Abramson, “Benign Metastasizing Leiomyoma: Clinical, Imaging, and Pathologic Correlation,” AJR, Vol. 176, No. 6, 2001, pp. 1409-1413. http://dx.doi.org/10.2214/ajr.176.6.1761409
[5] F. Spamaz, M. Ergin, O. Katrancioglu, T. Gonlugur, U. Gonlugur and S. Elagoz, “Benign Metastasizing Leiomyoma,” Lung, Vol. 186, No. 4, 2008, pp. 271-273. http://dx.doi.org/10.1007/s00408-008-9084-8
[6] V. Scioscio, P. Feraco, L. Miglio, F. Toni, D. Malvi, A. M. Pacilli, L. Fasano, M. Fabbri and M. Zompatori, “Benign Metastasizing Leiomyoma of the Lung: PET Findings,” Journal of Thoracic Imaging, Vol. 24, No. 1, 2009, pp. 41-44. http://dx.doi.org/10.1097/RTI.0b013e31818a0840
[7] X. Lin, W. Fan, P. Lang, Y. Hu, X. Zhang and X. Sun, “Benign Metastasizing Leiomyoma Identified Using 18FFDG PET/CT,” International Journal of Gynecology & Obstetrics, Vol. 110, No. 2, 2010, pp. 154-156. http://dx.doi.org/10.1016/j.ijgo.2010.03.017
[8] X. Jin, Y. Meng, Z. Zhu, H. Jing and F. Li, “Elevated 99mTc 3PRGD2 Activity in Benign Metastasizing Leiomyoma,” Clinical Nuclear Medicine, Vol. 38, No. 2, 2013, pp. 117-119. http://dx.doi.org/10.1097/RLU.0b013e318279f14d
[9] M. Ogawa, M. Hara, Y. Ozawa, S. Moriyama, M. Yano, S. Shimizu and Y. Shibamoto, “Benign Metastasizing Leiomyoma of the Lung with Malignant Transformation Mimicking Mediastinal Tumor,” Clinical Imaging, Vol. 35, No. 5, 2011, pp. 401-404. http://dx.doi.org/10.1016/j.clinimag.2010.11.003
[10] O. L. Manfredi and J. E. Aruny, “The Role of 99mTc-Bound Phosphates and Grey Scale Echography in the Differentiation of Pelvic Tumors,” Clinical Nuclear Medicine, Vol. 4, No. 3, 1979, pp. 99-107. http://dx.doi.org/10.1097/00003072-197903000-00004

Copyright © 2022 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.