Radical Scavenging and Antioxidant Potential of Nuts and Leaves Extracts of Semecarpus anacardium (L.)

DOI: 10.4236/ajps.2013.48204   PDF   HTML     3,492 Downloads   5,369 Views   Citations

Abstract

In the present investigation, antioxidant activity of the crude extracts from nuts and leaves of S. anacardium was carried out. The antioxidant potential of various extracts (ethanol, acetone and aqueous) of S. anacardium was determined by using DPPH assay, ABTS assay and metal chelating activity assay. Among the extracts the ethanol extract of nut showed significant scavenging activity (DPPH-88.73 ± 2.26; ABTS assay-81.65 ± 1.57 and metal chelating activity-72.37 ± 2.26) compared with antioxidant controls, ascorbic acid and BHA respectively. The findings of the present investigation suggest that the S. anacardium extracts can prove to be a potent source of biologically active compounds that can be further subjected to isolation of therapeutic antioxidant agents.

Share and Cite:

N. Barman, A. Sharma and A. Kumar, "Radical Scavenging and Antioxidant Potential of Nuts and Leaves Extracts of Semecarpus anacardium (L.)," American Journal of Plant Sciences, Vol. 4 No. 8, 2013, pp. 1679-1683. doi: 10.4236/ajps.2013.48204.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] R. Palaniswamy and P. R. Padma, “Free Radical Scavenging Activity of Majorana hortensis Leaves,” Ancient Science of Life, Vol. 30, No. 4, 2011, pp. 96-99.
[2] W. Droge, “Free Radicals in the Physiological Control of Cell Function,” Physiological Reviews, Vol. 82, No. 1, 2002, pp. 47-95.
[3] N. Ali, I. Shah, S. W. Shah, G. Ahmed, M. Shoaib, M. Junaid, W. Ali and Z. Ahmed, “Antioxidant and Relaxant Activity of Fractions of Crude Methanol Extract and Essential Oil of Artemisia macrocephala Jacquem,” BMC Complementary and Alternative Medicine, Vol. 13, 2013, p. 96. doi:10.1186/1472-6882-13-96
[4] B. Mahdi-Pour, S. L. Jothy, L.Y. Latha, Y. Chen, S. Sasidharan and S. Dharmaraj, “Antioxidant Activity of Methanol Extracts of Different Parts of Lantana camara,” Asian Pacific Journal of Tropical Medicine, Vol. 2, No. 12, 2012, pp. 960-965. doi:10.1016/S2221-1691(13)60007-6
[5] C. R. S. Al Nomaani, M. A. Hossain, A. M. Weli, Q. AlRiyami, J. N. Al-Sabahi and S. M. Rahman, “Chemical Composition of Essential Oils and in Vitro Antioxidant Activity of Fresh and Dry Leaves Crudeextracts of Medicinal Plant of Lactuca sativa L. Native to Sultanate of Oman,” Asian Pacific Journal of Tropical Medicine, Vol. 3, No. 5, 2013, pp. 353-357. doi:10.1016/S2221-1691(13)60076-3
[6] S. Sannigrahi, U. K. Mazuder, D. K. Pal, S. Parida and S. Jain, “Antioxidant Potential of Crude Extracts and Different Fractions of Enhydra fluctuans Lour,” Iranian Journal of Pharmaceutical Research, Vol. 9, No. 1, 2010, pp. 75-82.
[7] K. M. Nardkarni, “Indian Material Medica,” 3rd Edition, Popular Prakashan Private Ltd., Bombay, 1976, pp, 1119-1125.
[8] R. N. Chopra, “Indigenous Drugs of India,” 2nd Edition, Academic Publishers, Calcatta. 1982.
[9] J. B. Lamture, N. M. Gondgaon, U. R. Nayak, B. K. Patwardhan and R. B. Ghooi, “Semecarpus anacardiumSeparation of the Bhilawanol A and Bhilawanol B and A Comparative Study of Their Growth Inhibitory Effect on Clostridium tetani and General Pharmacology,” Bulletin of Haffkine Institute, Vol. 10, 1982, pp. 87-92.
[10] S. S. N. Murthy, “Jeediflavanone—A Biflavonoid from Semecarpus anacardium,” Phytochemistry, Vol. 24, No. 5, 1985, pp. 1065-1070. doi:10.1016/S0031-9422(00)83184-2
[11] S. S. N. Murthy, “Semecarpuflavanone a New Biflavanone from Semecarpus anacardium,” Proceeding of the Indian Academy of Science Chemical Sciences, Vol. 97, No. 1, 1986, pp. 63-70.
[12] R. R. Gil, L. Z. Lin, G. A. Cordell, M. R. Kumar, M. Ramesh, B. M. Reddy and A. V. N. Appa Rao, “Anacardoside from the Seeds of Semecarpus anacardium,” Phytochemistry, Vol. 39, No. 2, 1995, pp. 405-407. doi:10.1016/0031-9422(94)00842-H
[13] T. R. Govindachari, B. S. Joshi, V. N. Kamat and N. Viswanathan, “The Phenolic Constituents of Semecarpus anacardium,” Indian Journal of Chemistry, Vol. 9, 1971, pp. 1044-1046.
[14] B. Premalatha, V. Muthulakshmi, T. Vijayalakshmi and P. Sachdanandam, “Semecarpus anacardium Nut Extract Induced Changes in Enzymic Antioxidants Studied in Aflatoxin B1 Caused Hepatocellular Carcinoma Bearing Wistar Rats,” International Journal of Pharmaceutics, Vol. 35, No. 3, 1997, pp. 161-166. doi:10.1076/phbi.35.3.161.13300
[15] A. Sharma, P. K. Verma and V. P. Dixit, “Effect of Semecarpus anacardium Fruits on Reproductive Function of Male Albino Rats,” Asian Journal of Andrology, Vol. 5, No. 2, 2003, pp. 121-124.
[16] T. K. Mohanta, J. K. Patra, S. K. Rath, D. K. Pal and H. N. Thatoi, “Evaluation of Antimicrobial Activity and Phytochemical Screening of Oils and Nuts of Semicarpus anacardium L.f. Scient,” RES Essay, Vol. 2, No. 11, 2007, pp. 486-490.
[17] A. Sharma, N. Barman and M. Malwal, “Antimicrobial Efficacy of Nut Oil of Semecarpus anacardium: A Marking Nut Tree,” Biotechnology, Vol. 9, No. 3, 2010, pp. 383-386. doi:10.3923/biotech.2010.383.386
[18] T. Vijayalakshmi, V. Muthulakshmi and P. Sachdanandam, “Effect of the Milk Extract of Semecarpus anacardium Nut on Adjuvant Arthritis: A Dose Dependent Study in Wistar Albino Rats,” General Pharmacology, Vol. 27, No. 7, 1996, pp. 1223-1226. doi:10.1016/S0306-3623(96)00042-0
[19] W. Brand-Williams, M. E. Cuvelier and C. Berset, “Use of Free Radical Method to Evaluate Antioxidant Activity,” Food Science and Technology, Vol. 28, No. 1, 1995, pp. 25-30.
[20] R. Re, N. Pellegrini, A. Proteggente, A. Pannala, M. Yang and C. Rice-Evans, “Antioxidant Activity Applying an Improved ABTS Radical Cation Decolorization Assay,” Free Radical Biology & Medicine, Vol. 26, No. 9-10, 1999, pp. 1231-1237. doi:10.1016/S0891-5849(98)00315-3
[21] J. Sabate, “The Contribution of Vegetarian Diets to Health and Disease: A Paradigm Shift,” The American Journal of Clinical Nutrition, Vol. 78, 2003, pp. 502-507.
[22] M. Valko, D. Leibfritz, J. Moncol, M.T.D. Cronin, M. Mazur and J. Telser, “Free Radicals and Antioxidants in Normal Physiological Functions and Human Disease,” The International Journal of Biochemistry & Cell Biology, Vol. 39, No. 1, 2007, pp. 44-84. doi:10.1016/j.biocel.2006.07.001
[23] J. S. Deng, C. S. Chi, S. S. Huang, P. H. Shie, T. H. Lin and G. J. Huang, “Antioxidant, Analgesic, and Anti-Inflammatory Activities of the Ethanolic Extracts of Taxillus liquidambaricola,” Journal of Ethnopharmacology, Vol. 137, No. 3, 2011, pp. 1161-1171. doi:10.1016/j.jep.2011.07.041
[24] J. He, B. Huang, X. Ban, J. Tian, L. Zhu and Y. Wang, “In Vitro and in Vivo Antioxidant Activity of the Ethanolic Extract from Meconopsis quintuplinervia,” Journal of Ethnopharmacology, Vol. 141, No. 1, 2012, pp. 104-110. doi:10.1016/j.jep.2012.02.006
[25] R. S. Policegoudra, S. Saikia, J. Das, P. Chattopadhyay, L. Singh and V. Veer, “Phenolic Content, Antioxidant Activity, Antibacterial Activity and Phytochemical Composition of Garcinia lancifolia,” Indian Journal of Pharmaceutical Sciences, Vol. 74, No. 3, 2012, pp. 268-271. doi:10.4103/0250-474X.106075
[26] S. S. Ali, N. Kasoju, A. Luthra, A. Singh, H. Sharanabasava, A. Sahu and U. Bora, “Indian Medicinal Herbs as Sources of Antioxidants,” Food Research International, Vol. 41, No. 1, 2008, pp. 1-15. doi:10.1016/j.foodres.2007.10.001
[27] C. Selvam, S. M. Jachak and K. K. Bhutani, “Cyclooxygenase Inhibitory Flavonoids from the Stem Bark of Semecarpus anacardium Linn,” Phytotherapy Research, Vol. 18, No. 7, 2004, pp. 582-584. doi:10.1002/ptr.1492
[28] A. K. Sahoo, N. Narayanan, S. Sahana, S. S. Rajan and P. K. Mukherjee, “In Vitro Antioxidant Potential of Semecarpus anacardium L.,” Pharmacologyonline, Vol. 3, 2008, pp. 327-335.
[29] S.L. Mishra, P. K. Sinhamahapatra, A. Nayak, R. Das and S. Sannigrahi, “In Vitro Antioxidant Potential of Different Parts of Oxoxylum indicum: A Comparative Study,” Indian Journal of Pharmaceutical Sciences, Vol. 72, No. 2, 2010, pp. 267-269. doi:10.4103/0250-474X.65013

  
comments powered by Disqus

Copyright © 2020 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.