Prevalence of Human Immunodeficiency Virus (HIV), Risk Behavior, and Recent Substance Use in a Sample of Urban Drug Users: Findings by Race and Sex

Abstract

The aim of the current study was to examine the prevalence of HIV, past six-month illicit drug use, and risk behaviors among a population of heavy drug users living in an urban setting. Although many studies investigate substance use, sex-risk behavior, and HIV by race and gender, no studies have examined these variables simultaneously. The current study seeks to fill this gap in the literature by exploring HIV prevalence among a predominantly heterosexual sample of recent substance users by injection drug use (IDU) status, race, and sex. Baseline data from the Baltimore site of the NEURO-HIV epidemiologic study was used in this study. This study examines neuropsychological and social-behavioral risk factors of HIV, hepatitis A, hepatitis B, and hepatitis C among both injection and non-injection drug users. Descriptive statistics and chi-square statistics were used in data analyses. Blood and urine samples were obtained to test for the presence of recent drug use, viral hepatitis, HIV, and other sexually transmitted diseases (STDs). Findings presented here have several important implications for HIV prevention and care among substance users. Intervention programs that incorporate substance use treatment in addition to HIV education, particularly with respect to substance use and sex risk behavior are imperative.

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R. C. Trenz, L. R. Pacek, M. Scherer, P. T. Harrell, J. Zur and W. W. Latimer, "Prevalence of Human Immunodeficiency Virus (HIV), Risk Behavior, and Recent Substance Use in a Sample of Urban Drug Users: Findings by Race and Sex," World Journal of AIDS, Vol. 2 No. 3, 2012, pp. 183-193. doi: 10.4236/wja.2012.23024.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] O. C. Nwanyanwu, S. Y. Chu, T. A. Green, J. W. Buehler and R. L. Berkelman, “Acquired-Immunodeficiency-Syndrome in the United-States Associated with Injecting Drug-Use, 1981-1991,” The American Journal of Drug and Alcohol Abuse, Vol. 19, No. 4, 1993, pp. 399-408. doi:10.3109/00952999309001630
[2] D. C. Des Jarlais, S. R. Friedman and W. Hopkins, “Risk Reduction for the Acquired Immunodeficiency Syndrome among Intravenous Drug Users,” Annals of Internal Medicine, Vol. 103, No. 5, 1985, pp. 755-759.
[3] R. E. Chaisson, A. R. Moss, R. Onishi, D. Osmond and J. R. Carlson, “Human Immunodeficiency Virus Infection in Heterosexual Intravenous Drug Users in San Francisco,” American Journal of Public Health, Vol. 77, No. 2, 1987, pp. 169-172. doi:10.2105/AJPH.77.2.169
[4] E. E. Schoenbaum, D. Hartel, P. A. Selwyn, et al., “Risk Factors for Human Immunodeficiency Virus Infection in Intravenous Drug Users,” The New England Journal of Medicine, Vol. 321, No. 13, 1989, pp. 874-879. doi:10.1056/NEJM198909283211306
[5] E. J. van Ameijden and R. A. Coutinho, “Maximum Impact of HIV Prevention Measures Targeted at Injecting Drug Users,” AIDS, 1998, Vol. 12, No. 6, pp. 625-633. doi:10.1097/00002030-199806000-00012
[6] R. Marx, S. O. Aral, R. T. Rolfs, C. E. Sterk and J. G. Kahn, “Crack, Sex, and STD,” Sexually Transmitted Diseases, Vol. 18, No. 2, 1991, pp. 92-101. doi:10.1097/00007435-199118020-00008
[7] R. J. Battjes, R. W. Pickens, Z. Amsel and L. S. Brown, Jr., “Heterosexual Transmission of Human Immunodeficiency Virus among Intravenous Drug Users,” The Journal of Infectious Diseases, Vol. 162, No. 5, 1990, pp. 1007-1011. doi:10.1093/infdis/162.5.1007
[8] I. H. Meyer and L. Dean, “Patterns of Sexual Behavior and Risk Taking among Young New York City Gay Men,” AIDS Education and Prevention, Vol. 7, Supplement 5, 1995, pp. 13-23.
[9] R. B. Hays, S. M. Kegeles and T. J. Coates, “High HIV Risk-Taking among Young Gay Men,” AIDS, Vol. 4, No. 9, 1990, pp. 901-907. doi:10.1097/00002030-199009000-00011
[10] G. F. Lemp, A. M. Hirozawa, D. Givertz, et al., “Seroprevalence of HIV and Risk Behaviors among Young Homosexual and Bisexual Men. The San Francisco/Berkeley Young Men’s Survey,” The Journal of the American Medical Association, Vol. 272, No. 6, 1994, pp. 449-454. doi:10.1001/jama.1994.03520060049031
[11] D. H. Osmond, K. Page, J. Wiley, et al., “HIV Infection in Homosexual and Bisexual Men 18 to 29 Years of Age: The San Francisco Young Men’s Health Study,” American Journal of Public Health, Vol. 84, No. 12, 1994, pp. 1933-1937. doi:10.2105/AJPH.84.12.1933
[12] J. Ruiz, M. Facer and R. K. Sun, “Risk Factors for Human Immunodeficiency Virus Infection and Unprotected Anal Intercourse among Young Men Who Have Sex with Men,” Sexually Transmitted Diseases, Vol. 25, No. 2, 1998, pp. 100-107. doi:10.1097/00007435-199802000-00007
[13] G. R. Seage III, K. H. Mayer, W. R. Lenderking, et al., “HIV and Hepatitis B Infection and Risk Behavior in Young Gay and Bisexual Men,” Public Health Reports, Vol. 112, No. 2, 1997, pp. 158-167.
[14] SAMHSA, “The NSDUH Report: HIV/AIDS and Substance Use,” Rockville, 1 December, 2010.
[15] Hygiene DoHaM, “Maryland Vital Statistics Annual Report,” 2009. http://vsa.maryland.gov/doc/09annual.pdf
[16] Hygiene MDoHaM, “Baltimore City HIV/AIDS Statistics Fact Sheet,” 2008.
[17] SAMHSA, “National Survey on Drug Use and Health,” 2007-2008.
[18] Enters for Disease Control and Prevention (CDC; 2008). Estimates of New HIV Infections in the United States.
[19] S. A. Strathdee and S. G. Sherman, “The Role of Sexual Transmission of HIV Infection among Injection and Non-Injection Drug Users,” Journal of Urban Health, Vol. 80, Supplement 3, 2003, pp. 7-14.
[20] I. Kuo, A. E. Greenberg, M. Magnus, et al., “High Prevalence of Substance Use among Heterosexuals Living in Communities with High Rates of AIDS and Poverty in Washington, DC,” Drug and Alcohol Dependence, 2011.
[21] L. Degenhardt, B. Mathers, P. Vickerman, T. Rhodes, C. Latkin and M. Hickman, “HIV in People Who Use Drugs 2 Prevention of HIV Infection for People Who Inject Drugs: Why Individual, Structural, and Combination Approaches Are Needed,” The Lancet, Vol. 376, No. 9737, 2010, pp. 285-301. doi:10.1016/S0140-6736(10)60742-8
[22] E. Volz, S. D. Frost, R. Rothenberg and L. A. Meyers, “Epidemiological Bridging by Injection Drug Use Drives an Early Hiv Epidemic,” Epidemics, Vol. 2, No. 3, 2010, pp. 155-164. doi:10.1016/j.epidem.2010.06.003
[23] A. Neaigus, S. R. Friedman, B. J. Kottiri and D. C. D. Jarlais, “HIV Risk Networks and HIV Transmission among Injecting Drug Users,” Evaluation and Program Planning, Vol. 24, No. 2, 2001, pp. 221-226. doi:10.1016/S0149-7189(01)00012-X
[24] D. J. Pilowsky, D. Hoover, B. Hadden, et al., “Impact of Social Network Characteristics on High-Risk Sexual Behaviors among Non-Injection Drug Users,” Substance Use & Misuse, Vol. 42, No. 11, 2007, pp. 1629-1649. doi:10.1080/10826080701205372
[25] R. C. Neblett, M. Davey-Rothwell, G. Chander and C. A. Latkin, “Social Network Characteristics and HIV Sexual Risk Behavior among Urban African American Women,” Journal of Urban Health, Vol. 88, No. 1, 2011, pp. 54-65. doi:10.1007/s11524-010-9513-x
[26] US Census Bureau, Maryland State Census, 2010. http://census.maryland.gov/
[27] D. Vlahov, J. C. Anthony, A. Munoz, et al., “The ALIVE Study, a Longitudinal Study of HIV-1 Infection in Intravenous Drug Users: Description of Methods and Characteristics of Participants,” NIDA Research Monograph, Vol. 109, 1991, pp. 75-100.
[28] M. M. Mitchell and W. W. Latimer, “Unprotected Casual Sex and Perceived Risk of Contracting HIV among Drug Users in Baltimore, Maryland: Evaluating the Influence of Non-Injection Versus Injection Drug User Status,” AIDS Care, Vol. 21, No. 2, 2009, pp. 221-230. doi:10.1080/09540120801982897
[29] J. Pallant, “SPSS Survival Manual,” McGraw-Hill, New York, 2007.
[30] SPSS, PASW Statistics 17, SPSS Inc., Chicago, 2009.
[31] D. C. Des Jarlais, K. Arasteh and S. R. Friedman, “HIV among Drug Users at Beth Israel Medical Center, New York City, the First 25 Years,” Substance Use & Misuse, Vol. 46, No. 2-3, 2011, pp. 131-139. doi:10.3109/10826084.2011.521456
[32] CDC CfDC, “Update to Racial/Ethnic Disparities in Diagnoses of HIV/AIDS-33 States, 2001-2005,” Center for Disease Control and Prevention, 2007.
[33] C. Latkin, W. Mandell, M. Oziemkowska, et al., “Using Social Network Analysis to Study Patterns of Drug-Use among Urban Drug-Users at High-Risk for HIV-AIDS,” Drug and Alcohol Dependence, Vol. 38, No. 1, 1995, pp. 1-9. doi:10.1016/0376-8716(94)01082-V
[34] C. A. Latkin, S. J. Kuramoto, M. A. Davey-Rothwell and K. E. Tobin, “Social Norms, Social Networks, and HIV Risk Behavior Among Injection Drug Users,” AIDS and Behavior, Vol. 14, No. 5, 2010, pp. 1159-1168. doi:10.1007/s10461-009-9576-4
[35] N. S. Padian, S. C. Shiboski and N. P. Jewell, “Female-to-Male Transmission of Human-Immunodeficiency-Virus,” The Journal of the American Medical Association, Vol. 266, No. 12, 1991, pp. 1664-1667. doi:10.1001/jama.266.12.1664
[36] I. Devincenzi, R. A. Ancellepark, J. B. Brunet, et al., “Comparison of Female to Male and Male to Female Transmission of HIV in 563 Stable Couples,” British Medical Journal, Vol. 304, No. 6830, 1992, pp. 809-813. doi:10.1136/bmj.304.6830.809
[37] R. Seng, M. Rolland, G. Beck-Wirth, et al., “Trends in Unsafe Sex and Influence of Viral Load among Patients Followed Since Primary HIV Infection, 2000 to 2009,” AIDS, 2011.
[38] M. Miller and A. Neaigus, “Sex Partner Support, Drug Use and Sex Risk among HIV-Negative Non-Injecting Heroin Users,” AIDS Care, Vol. 14, No. 6, 2002, pp. 801-813. doi:10.1080/0954012021000031877
[39] S. B. Montgomery, J. Hyde, C. J. De Rosa, et al., “Gender Differences in HIV Risk Behaviors among Young Injectors and Their Social Network Members,” The American Journal of Drug and Alcohol Abuse, Vol. 28, No. 3, 2002, pp. 453-475. doi:10.1081/ADA-120006736
[40] M. Miller, C. T. Korves and T. Fernandez, “The Social Epidemiology of HIV Transmission among African American Women Who Use Drugs and Their Social Network Members,” AIDS Care-Psychological and Socio-Medical Aspects of AIDS/HIV, Vol. 19, No. 7, 2007, pp. 858-865.
[41] Control CfD, “Update to Racial/Ethnic Disparities in Diagnoses of HIV/AIDS-33 States, 2001-2005,” 2007.
[42] I. Devincenzi, “Heterosexual Transmission of HIV,” The Journal of the American Medical Association, Vol. 267, No. 14, 1992, pp. 1919-1919. doi:10.1001/jama.267.14.1919
[43] D. Castor, D. J. Pilowsky, B. Hadden, et al., “Sexual Risk Reduction among Non-Injection Drug Users: Report of a Randomized Controlled Trial,” AIDS Care-Psychological and Socio-Medical Aspects of AIDS/HIV, Vol. 22, No. 1, 2010, pp. 62-70.
[44] Group NMHSPTfAAC, “The Contribution of Male and Female Partners’ Substance Use to Sexual Risks and STDs among African American HIV Serodiscordant Couples,” AIDS and Behavior, Vol. 14, No. 5, 2010, pp. 1045-1054. doi:10.1007/s10461-010-9695-y
[45] D. L. Jones, D. Waldrop-Valverde, P. Gonzalez, et al., “Mental Health in HIV Seronegative and Seropositive IDUs in South Florida,” AIDS Care, Vol. 22, No. 2, 2010, pp. 152-158. doi:10.1080/09540120903039851
[46] S. Darke, “Self-Report among Injecting Drug Users: A review,” Drug and Alcohol Dependence, Vol. 51, No. 3, 1998, pp. 253-263. doi:10.1016/S0376-8716(98)00028-3
[47] SAMHSA, “HIV/AIDS and Substance Use,” 2010.
[48] F. L. Altice, A. Kamarulzaman, V. V. Soriano, M. Schechter and G. H. Friedland, “Treatment of Medical, Psychiatric, and Substance-Use Comorbidities in People Infected with HIV Who Use Drugs,” The Lancet, Vol. 376, No. 9738, 2010, pp. 367-387. doi:10.1016/S0140-6736(10)60829-X
[49] M. S. Friedman, M. P. Marshal, R. Stall, et al., “Associations between Substance Use, Sexual Risk Taking and HIV Treatment Adherence among Homeless People Living with HIV,” AIDS Care, Vol. 21, No. 6, 2009, pp. 692-700. doi:10.1080/09540120802513709
[50] L. N. Drumright and G. N. Colfax, “HIV Risk and Prevention for Non-Injection Substance Users, in HIV Prevention: A Comprehensive Approach,” Academic Press, Burlington, 2009.
[51] S. Magura, S. Y. Kang and J. L. Shapiro, “Outcomes of Intensive AIDS Education for Male Adolescent Drug Users in Jail,” Journal of Adolescent Health, Vol. 15, No. 6, 1994, pp. 457-463. doi:10.1016/1054-139X(94)90492-L
[52] J. S. Lawrence, R. A. Crosby, T. L. Brasfield and R. E. O’Bannon III, “Reducing STD and HIV Risk Behavior of Substance-Dependent Adolescents: A Randomized Controlled Trial,” Journal of Consulting and Clinical Psychology, Vol. 70, No. 4, 2002, pp. 1010-1021. doi:10.1037/0022-006X.70.4.1010
[53] W. M. Wechsberg, W. K. Luseno, R. S. Karg, et al., “Alcohol, Cannabis, and Methamphetamine Use and Other Risk Behaviours among Black and Coloured South African Women: A Small Randomized Trial in the Western Cape,” International Journal of Drug Policy, Vol. 19, No. 2, 2008, pp. 130-139. doi:10.1016/j.drugpo.2007.11.018

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