The Challenges of Diagnosing Disseminated Lyme Disease in a Patient with CLL

Abstract

The diagnosis of Lyme disease may be a challenge in patients with Chronic Lymphocytic Leukemia. In relying on detection of antibodies in the serum for diagnosis we are presented with a problem in our patients with CLL in whom there is hypogammaglobulinemia secondary to B-cell malfunction. We suggest the use of PCR in aiding in diagnosis of Lyme disease in patients with CLL.

Share and Cite:

S. Futuri, A. Malik and D. Shani, "The Challenges of Diagnosing Disseminated Lyme Disease in a Patient with CLL," Open Journal of Blood Diseases, Vol. 2 No. 1, 2012, pp. 14-15. doi: 10.4236/ojbd.2012.21003.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] C. D. Schweighofer, et al., “Lyme Disease in a Patient with Chronic Lymphocytic Leukemia Mimics Leukemic Meningeosis,” Onkologie, Vol. 30, No. 11, 2007, pp. 564-566. doi:10.1159/000108920
[2] M. Kalac, et al., “Central Nervous System Involvement of Previously Undiagnosed Chronic Lymphocytic Leukemia in a Patient with Neuroborreliosis,” International Journal of Hematology, Vol. 85, No. 4, 2007, pp. 323-325. doi:10.1532/IJH97.E0618
[3] L. Cerroni, et al., “Specific Cutaneous Infiltrates of B-Cell Chronic Lymphocytic Leukemia (B-CLL) at Sites Typical for Borrelia burgdorferi Infection,” Journal of Cutaneous Pathology, Vol. 29, No. 3, 2002, pp. 142-147. doi:10.1034/j.1600-0560.2002.290303.x

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.