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Cardio-Toxicity during chemotherapy: feasibility of new diagnostic approaches

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DOI: 10.4236/health.2010.24056    4,671 Downloads   9,395 Views  

ABSTRACT

Chemotherapy induced cardio-toxicity is a well known side effect of anticancer treatments, moreover the 70% of all tumors involve patients over 65 years-old, frequently with cardiac co- morbidity. We evaluated the feasibility of the application during chemotherapy administration of some of the most recent diagnostic techniques as 12-diagnostic leads telemetry, 7 days EKG monitoring device (R-Test Evolution 3R), blood level dosage of Brain Natriuretic Peptide (BNP) and Ischemia Modified Albumin (IMA). Some sub-clinical changes in the investigated parameters were found in patients undergoing chemotherapy, mostly containing fluorouracil, as shown in the following paper. Far from suggesting a widespread use of these methods during chemotherapy administration, we think that some more tools are needed to prevent cardiac toxicity in high-risk patients and some of what we studied may deserve further valuation in chemotherapy clinical trials.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Zustovich, F. , Trivellato, M. , Ceravolo, R. , Pastorelli, D. , Canton, R. , Buratin, L. , Mion, M. , Zaninotto, M. , Mattiazzi, M. , Plebani, M. and Cartei, G. (2010) Cardio-Toxicity during chemotherapy: feasibility of new diagnostic approaches. Health, 2, 376-380. doi: 10.4236/health.2010.24056.

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