UHPLC-DAD-ESI-MS/MS Analysis of Flavonoids from Ethanolic Extracts of Theobroma cacao Husk in Cuba - Open Access Library Journal

OALibJ > Vol.6 No.5, May 2019

Open Access Library Journal

Volume 6, Issue 5 (May 2019)

ISSN Print: 2333-9705 ISSN Online: 2333-9721

Google-based Impact Factor: 0.73 Citations

UHPLC-DAD-ESI-MS/MS Analysis of Flavonoids from Ethanolic Extracts of Theobroma cacao Husk in Cuba ()

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DOI: 10.4236/oalib.1105439 517 Downloads 1,212 Views Citations

Author(s)

José González¹, Danae Pérez², Enrique Gómez¹, Damaris de la C. Salgado¹, Max Monan³

Affiliation(s)

¹Departamento de Farmacia, Instituto de Farmacia y Alimentos, Universidad de La Habana, La Coronela, La Lisa, La Habana, Cuba.
¹Departamento de Farmacia, Instituto de Farmacia y Alimentos, Universidad de La Habana, La Coronela, La Lisa, La Habana, Cuba.
²Departamento de Alimentos, Instituto de Farmacia y Alimentos, Universidad de La Habana, La Coronela, La Lisa, La Habana, Cuba.
³ARVARNAM, 16 lot. les Rosiers, Quartier Thoraille, Rivière-Salée, Martinica, France.

ABSTRACT

A sample of ethanolic extracts of the husk of Theobroma cacao L. was scru-tinized using a UHPLC/DAD/MS Thermo scientific Dionex Ultimate 3000 RS coupled to a Thermo scientific LTQ XL mass spectrometer. In addition, about seven different chemical compounds were tentatively identified in this species based on chromatography retention time (Rt), UV and MS/MS spectra and compared with those of isolated authentic compound and literature data. Information obtained from these studies can be used as markers in the identification and standardization of this plant as a herbal remedy and also towards monograph development on the plant.

KEYWORDS

UHPLC, MS, Flavonoids, Ethanolic Extracts, Theobroma Cacao

Share and Cite:

González, J. , Pérez, D. , Gómez, E. , la C. Salgado, D. and Monan, M. (2019) UHPLC-DAD-ESI-MS/MS Analysis of Flavonoids from Ethanolic Extracts of Theobroma cacao Husk in Cuba. Open Access Library Journal, 6, 1-8. doi: 10.4236/oalib.1105439.

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