Author(s)

Kambiz Yazdanpanah¹, Farshad Sheykhesmeeili², Baran Parhizkar³, Abbas Ghasemi^4*

¹Associate Professor, Department of Hepatology and Gastroenterology, Towhid Hospital, University of Kurdistan, Head of Department of Internal, University of Kurdistan, Kurdistan, Iran.
²Assistant Professor and Head of Department of Hepatology and Gastroenterology, Towhid Hospital, University of Kurdistan, Kurdistan, Iran.
³Assistant Professor, Department of Hepatology and Gastroenterology, Towhid Hospital, University of Kurdistan, Kurdistan, Iran.
⁴Chief Resident of Internal Medicine, Department of Hepatology and Gastroenterology, Towhid Hospital, University of Kurdistan, Kurdistan, Iran.

Background and objective: Cirrhosis affects hundreds of millions of patients all around the world. Vitamin D deficiency is frequently observed in chronic hepatic disease. Vitamin D level may be an important survival marker in advanced liver cirrhosis. Material and Methods: The study is a sectional one of the descriptive-analytical type, where 90 of the patients with hepatic cirrhoses were selected with census sampling method. In all the cirrhotic patients, for diagnosis in clinical findings, the serological marker, autoantibodies were stable; biochemical endoscopy and imaging were the histological evidence and examinations and were then analyzed by SPSS version 22 software. Results: Based on the study, from the aspect of Child-Pugh classification, the highest vitamin D levels had the highest value in Child-Pugh class A with a frequency of 13 (43%) in the form of insufficiency, and had the highest value in Child-Pugh class B and C in the form of slight deficiency. Conclusion: It was specified based on the results obtained from the research that different vitamin D levels and liver failure severity have a significant relationship with each other (p < 0.05) in patients suffering from hepatic cirrhosis, such that the serum vitamin D level decreases as liver failure severity increases.

Cirrhosis, Vitamin D, Liver, Child-Pugh

Yazdanpanah, K. , Sheykhesmeeili, F. , Parhizkar, B. and Ghasemi, A. (2017) Serum Vitamin D Levels and Severity of Liver Dysfunction in Cirrhotic Patients. International Journal of Clinical Medicine, 8, 402-411. doi: 10.4236/ijcm.2017.86038.