Comparative Study on Nigerian Wild and Edible Beans in Reversing Incidence of Colon Cancer in Albino Rats - Open Access Library Journal

OALibJ > Vol.3 No.7, July 2016

Open Access Library Journal

Volume 3, Issue 7 (July 2016)

ISSN Print: 2333-9705 ISSN Online: 2333-9721

Google-based Impact Factor: 0.73 Citations

Comparative Study on Nigerian Wild and Edible Beans in Reversing Incidence of Colon Cancer in Albino Rats ()

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DOI: 10.4236/oalib.1102708 834 Downloads 1,827 Views Citations

Author(s)

O. A. Awoyinka¹, A. Ileola², C. N. Imeoria³, A. E. Omonisi⁴, F. C. Oladele¹, M. F. Asaolu²

Affiliation(s)

¹Department of Medical Biochemistry, College of Medicine, Ekiti State University, Ado Ekiti, Nigeria.
²Department of Biochemistry, Ekiti State University, Ado Ekiti, Nigeria.
³Department of Science Laboratory Technology, Ekiti State University, Ado Ekiti, Nigeria.
⁴Department of Anatomic Pathology, College of Medicine, Ekiti State University, Ado Ekiti, Nigeria.

ABSTRACT

This work is an investigation of the curative effects of some edible and wild type beans on colonic inflammation induced by Dextran Sulphate Sodium (DSS) in wister albino rats. Macroscopic examination performed on the colon after seven-day exposure of the animals to both DSS and bean sample revealed a high incidence of colonic inflammation in rats fed with macuna compared to other groups. However, from the histological examination, the groups fed with Otili and Feregede had a low incidence of dysplasia showing Otili and Feregede to be good candidates that could mitigate effect of Dextran Sodium Sulphate.

KEYWORDS

Dextran Sodium Sulphate (DSS) Otili, Feregede, Pakala, Mucuna, Colon Cancer

Share and Cite:

Awoyinka, O. , Ileola, A. , Imeoria, C. , Omonisi, A. , Oladele, F. and Asaolu, M. (2016) Comparative Study on Nigerian Wild and Edible Beans in Reversing Incidence of Colon Cancer in Albino Rats. Open Access Library Journal, 3, 1-7. doi: 10.4236/oalib.1102708.

Cited by

[1]	Dysbiosis in Obese Wister Rats fed with Pakala (Phaseolus lunatus) and Iru (Parkia biglobosa)" Awoyinka, OA," Omodara, TR," Oladele, FC," Alese, MO" …
	2020

[2]	In-Vitro Metabolite Colonic Production from Otili (Sphenostylis stenocarpa) as Influenced by Selected Gastrointestinal Microbes
	2018

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