Author(s)

Hanaa Hameed Haddad

Chemistry Department, College of Scienc, Basrah University, Basrah, Iraq.

Schiff base synthesis is usually acid catalyzed and it usually requires refluxing the mixture of aldehydes and amine in ethanolic solution. Synthesis and characterization of Schiff base ligands derived from substituted amine and salicylaldehyde and their complexes (Cu²⁺, Co²⁺) are reported. The ligands and ligand-complexes were characterized by melting point, FTIR, CHN-elemental analysis and UV-Visible analysis. The UV-Visible and elemental analysis of complexes established (1:2) mole ratio (M:L). The stability constant and thermodynamic parameters (K, ΔG, ΔH, ΔS) were determined at different temperature (30 - 40)°C which established that the metal-complexes were very stable. The review describes the promising biological activities of Schiff base and their metal complexes.

Schiff Base Derivatives, Complexes, Thermodynamic Parameters, FTIR-Spectra, Mole Ratio Method, CHN Analysis, Biological Activity Studies

Haddad, H. (2016) A New Schiff Base Derivatives Designed to Bind Metal Ion (Cu, Co): Thermodynamics and Biological Activity Studies. American Journal of Analytical Chemistry, 7, 446-451. doi: 10.4236/ajac.2016.75041.