Author(s)

Noman Q. Al-Naggar^*

Biomedical Engineering Department, University of Science and Technology, Sana’a, Yemen.

A mathematical model of mechanical ventilator describes its behavior during artificial ventilation. This paper purposes to create and simulate Mathematical Model (MM) of Pressure Controlled Ventilator (PCV) signal. This MM represents the respiratory activities and an important controlled parameter during mechanical ventilation—Positive End Expiration Pressure (PEEP). The MM is expressed and modelled using periodic functions with inequalities to control the beginning of inspiration and expiration durations. The created MM of PCV signal is combined with an existing multi compartmental model of respiratory system that is modified and developed in the internal parameters—compliances (C) to test created MM. The created MM and model of respiratory system are constructed and simulated using Simulink package in MATLAB platform. The obtained simulator of mechnical ventilation system could potentially represent the pressure signal of PVC as a complete respiratory cycle and continuance waveform. This simulator is also able to reflect a respiratory mechanic by changing some input variables such as inspiration pressure (IP), PEEP and C, which are monitored in volume, flow, pressure and PV loop waveforms. The obtained simulator has provided a simple environment for testing and monitoring PCV signal and other parameters (volume, flow and dynamic compliance) during artificial ventilation. Furthermore, the simulator may be used for studying in the laboratory and training ventilator’s operators.

Mechanical Ventilator, Mathematical Model, Pressure Controlled Ventilator, PEEP, PV Loop, Compliance

Al-Naggar, N. (2015) Modelling and Simulation of Pressure Controlled Mechanical Ventilation System. Journal of Biomedical Science and Engineering, 8, 707-716. doi: 10.4236/jbise.2015.810068.