Open Journal of Ophthalmology

Volume 4, Issue 3 (August 2014)

ISSN Print: 2165-7408   ISSN Online: 2165-7416

Google-based Impact Factor: 0.27  Citations  

Intravitreal Bevacizumab for the Treatment of Chronic or Recurrent Central Serous Chorioretinopathy

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DOI: 10.4236/ojoph.2014.43010    3,439 Downloads   4,973 Views  Citations

ABSTRACT

Background: We report the use of intravitreal bevacizumab as an option for the treatment of chronic or recurrent central serous chorioretinopathy (CSC). Methods: Eight eyes with chronic or recurrent CSC received intravitreal bevacizumab (1.25 mg/0.05 cc) and underwent best corrected visual acuity (VA), optical coherent tomography (OCT), fluorescein angiography (FA) and indocyanine green angiography (ICG) before, and one, three and six months after treatment. Results: All patients showed improvement in visual acuity, fluorescein angiographic leakage, choroidal hyperpermeability and reduced or resolved neurosensory detachment following treatment. Two patients require a second dose of intravitreal bevacizumab. Conclusions: Intravitreal injection of bevacizumab was associated with visual improvement and reduced neurosensory detachment without adverse events in patients with chronic or recurrent CSC. Although these results are promising, further investigations would be helpful to understand this therapy for patients with CSC.

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Torres Soriano, M.E., García Aguirre, G., Gordon Angelozzi, M., Kon Jara, V., Fromow Guerra, J., Ober, M.D. and Quiroz Mercado, H. (2014) Intravitreal Bevacizumab for the Treatment of Chronic or Recurrent Central Serous Chorioretinopathy. Open Journal of Ophthalmology, 4, 57-64. doi: 10.4236/ojoph.2014.43010.

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