Author(s)

Ming Zheng, Mingqiang Zeng, Chonghe Jiang, Jinyang Chen, Shuren Li, Jiaxin Wang

Department of Urology, Qingyuan City People’s Hospital of Jinan University, Qingyuan, China.
Department of Urology, Xiangtan Hospital of Nanhua University, Xiangtan, China.

Objective: To evaluate the efficacy and safety of terazosin and plasma kinetic resection of the prostate (PKRP) in the treatment of benign prostatic hyperplasia (BPH) patients with coexisting hypertension. Methods: A total of 205 men who suffered from BPH with concomitant hypertension were enrolled in this study. They all received PKRP surgery and terazosin medication from one week before to 3 months after the operation. The procedures of efficacy and safety were evaluated by analysis of the changes in blood pressures, IPSS, Qmax and the drug related adverse events 4 weeks and 3 months after the operation. Results: The systolic blood pressure decreased from 161 ± 12.33 mmHg at baseline to 148 ± 7.27 mmHg four weeks (P < 0.05) and to 132 ± 6.13 mmHg three months after the operation (P < 0.01), the diastolic blood pressure decreased from 102 ± 4.99 mmHg to 95 ± 4.61 mmHg four weeks (P < 0.05) and to 81 ± 4.26 mmHg three months after the operation (P < 0.01). The IPSS reduced from 21 ± 4.82 to 15 ± 3.66 four weeks (P < 0.05) and to 12 ± 3.11 three months after the operation (P < 0.01). The Qmax were improved from 7 ± 4.41 to 12 ± 1.34 four weeks and to 15 ± 2.92 three months after the operation (P < 0.05). There were no notable adverse events. Conclusions: PKRP combined with terazosin in treating BPH with concomitant hypertension patient is a safe and effective procedure with a good patient compliance.

Benign Prostatic Hyperplasia, Hypertension, Terazosin, Plasma Kinetic Vaporization of the Prostate

Zheng, M. , Zeng, M. , Jiang, C. , Chen, J. , Li, S. and Wang, J. (2014) Plasma Kinetic Resection of Prostate Combined Terazosin for Treatment of BPH Patient with Coexisting Hypertension. Open Journal of Urology, 4, 57-62. doi: 10.4236/oju.2014.45010.