Remission of arthritis but persistent cutaneous lesions following tocilizumab treatment in a RA-patient suffering from concomitant psoriasis - Case Reports in Clinical Medicine

CRCM > Vol.2 No.1, March 2013

Volume 2, Issue 1 (March 2013)

ISSN Print: 2325-7075 ISSN Online: 2325-7083

Google-based Impact Factor: 0.2 Citations

Remission of arthritis but persistent cutaneous lesions following tocilizumab treatment in a RA-patient suffering from concomitant psoriasis ()

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DOI: 10.4236/crcm.2013.21018 3,668 Downloads 5,621 Views Citations

Author(s)

Wolfgang Hartung, Boris Ehrenstein, Rotraud Wallisch, Martin Fleck

Affiliation(s)

Department of Rheumatology/Clinical Immunology, Asklepios-Hospital, Bad Abbach, Germany.

ABSTRACT

Modulation of the interleukin-6 pathway with tocilizumab has been demonstrated to be highly effective in substantial numbers of patients suffering from rheumatoid arthritis (RA), and juvenile idiopathic arthritis. A pivotal role of the IL-6 pathway has been also established in other autoimmune conditions including psoriasis and psoriatic arthritis, becoming attractive targets for therapeutic IL-6 inhibition. Here, we describe the first case of tocilizumab treatment in a RA-patient suffering from concomitant severe psoriasis, who achieved remission of RA, whereas no improvement of psoriatic lesions could be observed.

KEYWORDS

Tocilizumab; Rheumatoid Arthritis; Psoriasis; Treatment

Share and Cite:

Hartung, W. , Ehrenstein, B. , Wallisch, R. and Fleck, M. (2013) Remission of arthritis but persistent cutaneous lesions following tocilizumab treatment in a RA-patient suffering from concomitant psoriasis. Case Reports in Clinical Medicine, 2, 63-65. doi: 10.4236/crcm.2013.21018.

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