Author(s)

Saleh Altuwaijri

SAAD Research Development Center (SRDC), Saad Specialist Hospital, Al Khobar 31952, Saudi Arabia.

Prostate cancer (PCa) is most common diagnosed cancer in men and it is second most common cause of male cancer death. Many factors have been implicated in the pathogenesis of PCa. Although many papers have discussed the prostate specific antigen (PSA) as biomarker of PCa, very few have addressed its rule in the carcinogenesis, metastasis and invasion of PCa. In this article we will review the pathological role of PSA, as a potential target in the therapeutics of PCa.

Prostate Cancer; Prostate Specific Antigen; PSA; Androgen Receptor

S. Altuwaijri, "Role of Prostate Specific Antigen (PSA) in Pathogenesis of Prostate Cancer," Journal of Cancer Therapy, Vol. 3 No. 4, 2012, pp. 331-336. doi: 10.4236/jct.2012.34043.