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Dr. Raymond T. F. Cheung

Division of Neurology, Department of Medicine

University of Hong Kong, HK

Clinical Professor

Lee Man-Chiu Professor in Neuroscience

Hong Kong West Cluster Hospitals

Hospital Authority, HK

Director of Acute Stroke Services

Honorary Consultant

Email: rtcheung@hkucc.hku.hk


1996 Ph.D., Physiology, University of Western Ontario, Canada

1987 M.B., Medicine, University of Hong Kong, Hong Kong

Research Fields

Cerebrovascular disease

Vascular dementia



Publications (selected)

  1. SANG, L.Y.H., LIANG, Y.X., WONG W.M., LI Y., TAY, D.K.C., SO, K.F., ELLIS-BEHNKE, R.G., WU, W.T., and CHEUNG, R.T.F., 2014. A self-assembling nanomaterial reduces acute brain injury and enhances functional recovery in a rat model of intracerebral hemorrhage Nanomedicine: Nanotechnology, Biology, and Medicine, Epub. ISSN 1549-9634. Available from: http://dx.doi.org/10.1016/j.nano.2014.05.012.
  2. LAU, K.K., WONG, Y.K., CHAN, Y.H., TEO, K.C., CHAN, K.H., LI, L.S.W., CHEUNG, R.T., SIU, C.W., HO, S.L., and TSE, H.F., 2014. Visit-to-visit blood pressure variability as a prognostic marker in patients with cardiovascular and cerebrovascular diseases - Relationships and comparisons with vascular markers of atherosclerosis. Atherosclerosis, vol. 235, no. 1, pp. 230-5. ISSN 0021-9150. Available from: http://dx.doi.org/10.1016/j.atherosclerosis.2014.04.015.
  3. LAU, K.K., WONG, Y.K., TEO, K.C., CHANG, R.S., CHAN, K.H., HON, S.F., WAT, K.L., CHEUNG, R.T., LI, L.S., SIU, C.W., and TSE, H.F., 2014. Long-Term Prognostic Implications of Visit-to-Visit Blood Pressure Variability in Patients With Ischemic Stroke. Am J Hypertens, Epub. ISSN 1879-1905. Available from: http://dx.doi.org/10.1093/ajh/hpu070.
  4. GAO, J., CHEUNG, R.T., CHAN, Y.S., CHU, L.W., MAK, H.K., and LEE, T.M., 2014. The relevance of short-range fibers to cognitive efficiency and brain activation in aging and dementia. PLoS One, vol. 9, no. 4: e90307. ISSN 1932-6203. Available from: http://dx.doi.org/10.1371/journal.pone.0090307.
  5. LAU, K.K., WONG, Y.K., TEO, K.C., CHANG, R.S., HON, S.F., CHAN, K.H., CHEUNG, R.T., LI, L.S., TSE, H.F., HO, S.L., and SIU, C.W., 2014. Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality. PLoS One, vol. 11, no. 2: e88283. ISSN 1932-6203. Available from: http://dx.doi.org/10.1371/journal.pone.0088283.
  6. LIU, L., and CHEUNG, R.T., 2013. Effects of pretreatment with a combination of melatonin and electroacupuncture in a rat model of transient focal cerebral ischemia. Evid Based Complement Alternat Med, vol. 2013: 953162. ISSN 1741-4288. Available from: http://dx.doi.org/10.1155/2013/953162.
  7. LAU, K.K., WONG, Y.K., CHANG, R.S., TEO, K.C., HON, S.F., CHAN, K.H., WAT, K.L., CHEUNG, R.T., LI, L.S., SIU, C.W., HO, S.L., and TSE, H.F., 2014. Visit-to-visit systolic blood pressure variability predicts all-cause and cardiovascular mortality after lacunar infarct. Eur J Neurol, vol. 21, no. 2: 319-25. ISSN 1468-1331 Available from: http://dx.doi.org/10.1111/ene.12310.
  8. TEO, K.C., MAHBOOBANI, N.R., LEE, R., SIU, C.W., CHEUNG, R.T., HO, S.L., LAU, K.K., and CHAN, K.H., 2014. Warfarin associated intracerebral hemorrhage in Hong Kong Chinese.Neurol Res,vol.36,no.2:143-9.Available from: http://dx.doi.org/10.1179/1743132813Y.0000000275.
  9. SANG, Y.H., LIANG, Y.X., LIU, L.G., ELLIS-BEHNKE, R.G., WU, W.T., SO, K.F., and CHEUNG, R.T., 2013. Rat model of intracerebral hemorrhage permitting hematoma aspiration plus intralesional injection. Exp Anim, vol. 62, no. 1:63-9. ISSN 1341-1357. Available from: http://dx.doi.org/10.1538/expanim.62.63.
  10. GAO, J.L., CHEUNG, R.T., CHAN, Y.S., CHU, L.W., and LEE, T.M., 2013. Increased prospective memory interference in normal and pathological aging: different roles of motor and verbal processing speed. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn, vol. 20, no. 1: 80-100. ISSN 1382-5585. Available from: http://dx.doi.org/10.1080/13825585.2012.672948.
  11. SANG, Y.H., SU, H.X., WU, W.T., SO, K.F., and CHEUNG, R.T., 2011. Elevated blood pressure aggravates intracerebral hemorrhage-induced brain injury. J Neurotrauma, vol. 28, no. 12: 2523-34. ISSN 1557-9042. Available from: http://dx.doi.org/10.1089/neu.2010.1680.
  12. TSO, A.W., LAM, T.K., XU, A., YIU, K.H., TSE, H.F., LI, L.S., LAW, L.S., CHEUNG, B.M., CHEUNG, R.T., and LAM, K.S., 2011. Serum adipocyte fatty acid-binding protein associated with ischemic stroke and early death. Neurology, vol. 76, no. 23: 1968-75. ISSN 0893-0341. Available from: http://dx.doi.org/10.1212/WNL.0b013e31821e54b3.
  13. GAO, J., CHEUNG, R.T., LEE, T.M., CHU, L.W., CHAN, Y.S., MAK, H.K., ZHANG, J.X., QIU, D., FUNG, G., and CHEUNG, C., 2011. Possible retrogenesis observed with fiber tracking: an anteroposterior pattern of white matter disintegrity in normal aging and Alzheimer's disease. J Alzheimers Dis, vol. 26, no. 1: 47-58. ISSN 1387-2877. Available from: http://dx.doi.org/10.3233/JAD-2011-101788.
  14. CHEUNG, R.T., LYDEN, P.D., TSOI, T.H., HUANG, Y., LIU, M., HON, S.F., RAMAN, and R., LIU, L., 2010. Production and validation of Putonghua- and Cantonese-Chinese language National Institutes of Health Stroke Scale training and certification videos. Int J Stroke, vol. 5, no. 2: 74-9. ISSN 1747-4949. Available from: http://dx.doi.org/10.1111/j.1747-4949.2010.00411.x.
  15. YU, J., ZENG, J., CHEUNG, R.T., XIONG, L., HE, M., LIANG, Z., HONG, H., and HUANG, R., 2009. Intracerebroventricular injection of epidermal growth factor reduces neurological deficit and infarct volume and enhances nestin expression following focal cerebral infarction in adult hypertensive rats. Clin Exp Pharmacol Physiol, vol. 36, no. 5-6: 539-46. ISSN 1440-1681. Available from: http://dx.doi.org/10.1111/j.1440-1681.2008.05105.x.
  16. LING, L., ZENG, J., PEI, Z., CHEUNG, R.T., HOU, Q., XING, S., and ZHANG, S., 2009. Neurogenesis and angiogenesis within the ipsilateral thalamus with secondary damage after focal cortical infarction in hypertensive rats. J Cereb Blood Flow Metab, vol. 29, no. 9: 1538-46. ISSN 0271-678X. Available from: http://dx.doi.org/10.1038/jcbfm.2009.76.
  17. SU, Y., ZHANG, X., ZENG, J., PEI, Z., CHEUNG, R.T., ZHOU, Q.P., LING, L., YU, J., TAN, J., and ZHANG, Z., 2009. New-onset constipation at acute stage after first stroke: incidence, risk factors, and impact on the stroke outcome. Stroke, vol. 40, no. 4: 1304-9. ISSN 0039-2499. Available from: http://dx.doi.org/10.1161/STROKEAHA.108.534776.
  18. CHEUNG, R.T., TIPOE, G.L., TAM, S., MA, E.S., ZOU, L.Y., and CHAN, P.S., 2006. Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration. J Pineal Res, vol. 41, no. 4: 337-43. ISSN 1600-079X. Available from: http://dx.doi.org/10.1111/j.1600-079X.2006.00372.x.
  19. LEE, T.M., ZHANG, J.X., CHAN, C.C., YUEN, K.S., CHU, L.W., CHEUNG, R.T., CHAN, Y.S., FOX, P.T., and GAO, J.H., 2006. Age-related differences in response regulation as revealed by functional MRI. Brain Res, vol. 1076, no. 1: 171-6. ISSN 0006-8993. Available from: http://dx.doi.org/10.1016/j.brainres.2005.12.124.
  20. LI, G., CHEUNG, R.T., GAO, J.H., LEE, T.M., TAN, L.H., FOX, P.T., JACK, C.R. Jr., YANG, E.S., 2006. Cognitive processing in Chinese literate and illiterate subjects: an fMRI study. Hum Brain Mapp, vol. 27, no. 2: 144-52. ISSN 1097-0193. Available from: http://dx.doi.org/10.1002/hbm.20173.
  21. CHEUNG, R.T., ELIASZIW, M., MELDRUM, H.E., FOX, A.J., BARNETT, H.J., and North American Symptomatic Carotid Endarterectomy Trial Group, 2003. Risk, types, and severity of intracranial hemorrhage in patients with symptomatic carotid artery stenosis. Stroke, vol. 34, no. 8: 1847-51. ISSN 0039-2499. Available from: http://dx.doi.org/10.1161/01.STR.0000080523.29138.5F.
  22. CHEUNG, R.T., and ZOU, L.Y., 2003. Use of the original, modified, or new intracerebral hemorrhage score to predict mortality and morbidity after intracerebral hemorrhage. Stroke, vol. 34, no. 7: 1717-22. ISSN 0039-2499. Available from: http://dx.doi.org/10.1161/01.STR.0000078657.22835.B9.
  23. PEI, Z., PANG, S.F., and CHEUNG, R.T., 2003. Administration of melatonin after onset of ischemia reduces the volume of cerebral infarction in a rat middle cerebral artery occlusion stroke model. Stroke, vol. 34, no. 3: 770-5. ISSN 0039-2499. Available from: http://dx.doi.org/ 10.1161/01.STR.0000057460.14810.3E.
  24. CHEUNG, R.T., 2003. The utility of melatonin in reducing cerebral damage resulting from ischemia and reperfusion. J Pineal Res, vol. 34, no. 3: 153-60. Available from: http://dx.doi.org/10.1034/j.1600-079X.2003.00034.x.
  25. LI, G., LIU, H.L., CHEUNG, R.T., HUNG, Y.C., WONG, K.K., SHEN, G.G., MA, Q.Y., YANG, E.S., 2003. An fMRI study comparing brain activation between word generation and electrical stimulation of language-implicated acupoints. Hum Brain Mapp, vol. 18, no. 3: 233-8. ISSN 1097-0193. Available from: http://dx.doi.org/10.1002/hbm.10098.

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