Dr. Jade Kenneth Forwood
Charles Sturt University, Australia
Associate Head
Email: jforwood@csu.edu.au
Qualifications
2002 Ph.D., Australian National University, Biochemistry and
Molecular Biology
1998 BBiomed. Sc (Hons I), James Cook University,
Biochemistry
Publications (selected)
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Smythe GM, Forwood JK. Altered mitogen-activated protein kinase
signaling in dystrophic (mdx) myotubes. Muscle Nerve, In press. (Accepted Jan
2012).
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Marfori M, Lonhienne T, Forwood JK, Kobe B. Structural
characterisation of the importin-α and high-affinity nuclear localization
signal interaction. In press (Accepted Nov 2011) Traffic.
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Swarbrick C, Roman N, Forwood JK. Functional and structural
characterization of Acot7 in macrophages and role in inflammation. Inflammatory
Diseases / Book 3, ISBN 979-953-307-659-0. 2011
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Marfori M, Mynott A, Ellis JJ, Mehdi AM, Saunders NF, Curmi PM,
Forwood JK, Bodén M, Kobe B. Molecular basis for specificity of nuclear import
and prediction of nuclear localization. Biochim Biophys Acta. 2011
Sep;1813(9):1562-77.
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Marfori M, Kobe B, Forwood JK. Ligand-induced conformational
changes within a hexameric Acyl-CoA thioesterase. J Biol Chem. 2011 Oct
14;286(41):35643-9.
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Kirkby B, Roman N, Kobe B, Kellie S, Forwood JK. Functional and
Structural Properties of Mammalian Acyl-Coenzyme A Thioesterases. Prog in Lipid
Research. Prog Lipid Res. 2010 Oct;49(4):366-77. Impact Factor = 11.23; ARC A
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Kaur G, Delluc-Clavieres A, Poon IK, Forwood JK, Glover DJ, Jans
DA. Calmodulin-dependent nuclear import of HMG-box family nuclear factors:
importance of the role of SRY in sex reversal. Biochem J. 2010 Jul
28;430(1):39-48. ARC A
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Forwood JK, Lange A, Zachariae U, Marfori M, Preast C, Grubmüller
H, Stewart M, Corbett AH, Kobe B. Quantitative Structural Analysis of
Importin-β Flexibility: Paradigm for Solenoid Protein Structures. Structure.
2010 Sep 8;18(9):1171-83. Impact Factor = 5.5 ARC A
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King GJ, Chena KE, Robin G, Forwood JK, Herasa B, Thakur AS, Kobe
B, Blomberg SP and Martin JL. Interaction Between Plate Make And Protein In
Protein Crystallisation Screening. PLOSone. 2009 Nov 16; 4(11):e7851
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Lonhienne TG*, Forwood JK*, Marfori M, Robin G, Kobe B, Carroll
BJ. Importin-beta is a GDP-TO-GTP exchange factor of RAN: Implications for the
mechanism of nuclear import. J Biol Chem. 2009 Jun 23. Impact Factor = 5.5
*Joint first authors
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Roman N, Kirkby B, Marfori M, Kobe B, Forwood JK. Crystallisation
of the flexible nuclear import receptor importin-beta. Acta Crystallograph Sect
F Struct Biol Cryst Commun. Accepted for publication. Impact Factor = 0.65
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Kobe B, Guncar G, Buchholz R, Huber T, Maco B, Cowieson N, Martin
JL, Marfori M, Forwood JK. Crystallography and protein-protein interactions:
biological interfaces and crystal contacts. Biochem Soc Trans. 2008:36:1438-41.
Impact Factor = 3.45
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Forwood JK, Lonhienne TG, Marfori M, Robin G, Meng W, Guncar G,
Liu SM, Stewart M, Carroll BJ, Kobe B. Kap95p Binding Induces the Switch Loops
of RanGDP to Adopt the GTP-Bound Conformation: Implications for Nuclear Import
Complex Assembly Dynamics. J Mol Biol. 2008; 383: 772-82. Impact Factor = 4.47
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Mouradov D, King G, Ross IL, Forwood JK, Hume DA, Sinz A, Martin
JL, Kobe B, Huber T. Protein structure determination using a combination of
cross-linking, mass spectrometry, and molecular modeling. Methods Mol Biol
2008;426:459-474.
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Meng W, Forwood JK, Guncar G, Robin G, Cowieson NP, Listwan P,
Mouradov D, King G, Ross IL, Robinson J, Puri M, Hill JM, Kellie S, Huber T,
Hume DA, Martin JL, Kobe B. Overview of the pipeline for structural and
functional characterization of macrophage proteins at the university of
Queensland. Methods Mol Biol 2008;426:577-587.
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Prior RJ and Forwood JK. A project-based learning approach to
protein biochemistry suitable for both face-to-face and distance education
students. UniServe Science Teaching and Learning Research Proceedings 2007.
181-188. (Double peer-reviewed).
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Robin G, Cowieson NP, Guncar G, Forwood JK, Listwan P, Hume DA,
Kobe B, Martin JL, Huber T. A general target selection method for
crystallographic proteomics. Methods Mol Biol 2008;426:27-35.
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Cowieson NP, Wensley B, Robin G, Guncar G, Forwood JK, Hume DA,
Kobe B, Martin JL. A medium or high throughput protein refolding assay. Methods
Mol Biol 2008;426:269-275.
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Forwood JK, Thakur AS, Guncar G, Marfori M, Mouradov D, Meng W,
Robinson J, Huber T, Kellie S, Martin JL, Hume DA, Kobe B. Structural basis for
recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in
inflammation. Proc Natl Acad Sci U S A 2007;104(25):10382-10387. Impact Factor
= 10.23
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Forwood JK, Kaur G, Jans DA. Nuclear import properties of the
sex-determining factor SRY. Methods Mol Biol 2007;390:83-97.
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Wang CA, Guncar G, Forwood JK, Teh T, Catanzariti A, Schirra H,
Anderson PA, Ellis JG, Dodds PN, Kobe B. Crystal structures of flax rust
avirulence proteins AvrL567-A and AvrL567–D reveal the structural basis for
flax disease resistance specificity. Plant Cell 2007; 19(9):2898-2912. Impact
Factor = 9.8
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Cowieson NP, Miles AJ, Robin R, Forwood JK, Kobe B, Wallace BA,
Martin JL. Evaluating Protein: Protein Complex Formation using Synchrotron
Radiation Circular Dichroism Spectroscopy. Proteins 2007: 70(4):1142-6. Impact
Factor = 4.8
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Forwood JK, Jans DA. Quantitative analysis of DNA-protein
interactions using double-labeled native gel electrophoresis and
fluorescence-based imaging. Electrophoresis 2006; 27(16):3166-3170. Impact
Factor = 3.85
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Guncar G, Wang CI, Forwood JK, Teh T, Catanzariti AM, Ellis JG,
Dodds PN, Kobe B. The use of Co2+ for crystallization and structure
determination, using a conventional monochromatic X-ray source, of flax rust
avirulence protein. Acta Crystallograph Sect F Struct Biol Cryst Commun 2007;
63(Pt 3):209-213. Impact Factor = 0.65
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