Prof. Blanca Bazán
Perkins
Departamento
de Investigación en Hiperreactividad Bronquial
Instituto
Nacional de Enfermedades Respiratorias, Mexico
Email: perkins@unam.mx
Qualifications
2001 Ph.D.,
Universidad Nacional Autónoma de México, Biomedicine
1994 M.Sc.,
Universidad Nacional Autónoma de México, Physiology
1991 B.Sc.,
Universidad Nacional Autónoma de México, Biology
Publications
(Selected)
1. 2015 Alvarez-Santos MD, Ramos-Ramirez P,
Gutierrez-Aguilar F, Sánchez-Hernandez S, Lascurain R, Olmos-Zuñiga R,
Jasso-Victoria R, Bobadilla NA, Bazán-Perkins B. Antigen-induced airway
hyperresponsiveness and obstruction is related to caveolin-1 expression in
airway smooth muscle in a guinea pig asthma model. Clinical and Translational
Allergy. 5:14.
2. 2015 Lucely Cetina, Tania Crombet, Roberto
Jiménez-Lima, Sergio Zapata, Mayra Ramos, Sandra Avila, Jaime Coronel, Eduardo
Charco, Rafael Bojalil, Horacio Astudillo, Blanca Bazán, Alfonso
Dueñas-González. A pilot study of nimotuzumab plus single agent chemotherapy as
second- or third-line treatment or more in patients with recurrent, persistent
or metastatic cervical cancer. Cancer Biology & Therapy 16 (5): 684-9
3. 2014 Ramos-Ramírez P, Campos MG,
Martínez-Cordero E, García-Zepeda E, Téllez-Jiménez O, Larios-Martínez K
Bazán-Perkins B. Neutrophilia induced by histamine challenge in guinea pig: The
role of IL‑5, IL‑10 and IL‑17A, but no CXCL8. Boletín Médico del Hospital
Infantil de México, 71 (2): 83-87..
4. Ramos-Ramírez P, Campos MG, Martínez-Cordero
E, Bazán-Perkins B, García-Zepeda E. Antigen-induced airway hyperresponsiveness
In absence of broncho-obstruction in sensitized guinea pigs. Experimental Lung
Research, 39, 136–145.
5. Oropeza M., Calzada C, Guerra-Araiza C.,
Bazán-Perkins B. Mendoza-Espinoza J. Campos MG, Tibolone induces serotonin,
estrogen and progesterone receptor expression but not contractile response to
serotonin in the rat uterus. Hormone and Metabolic Research 45 (7): 490-4.
6. 2012 Bazán-Perkins B. cGMP reduces the
sarcoplasmic reticulum Ca2+ loading in airway smooth muscle cells: a putative
mechanism in the regulation of Ca2+ by cGMP Journal of Muscle Research
and Cell Motility, 32 (6): 375-82.
7. 2011 Campos M.G., Bazán-Perkins B.
Asthma: relationships and mechanisms. Boletín Médico del Hospital Infantil de
México 68 (3): 169-170.
8. 2010 Vargas MH, Sommer B,
Bazán-Perkins B, Montaño LM. Airway responsiveness measured by barometric
plethysmography in guinea pigs. Veterinary Research Communications, 34 (7):
589-596.
9. 2010 Sánchez-Pozos K., Lee-Montiel F.,
Pérez R., Uribe N., Gamba G., Bazan-Perkins B., Bobadilla N.A.
Polymerized type I collagen reduces chronic cyclosporine (CsA) nephrotoxicity.
Nephrology Dialysis Transplantation 25 (7): 2150-2158.
10. 2010 Moreno-Álvarez P.,
Sánchez-Guerrero E., Martínez-Cordero E., Hernández-Pando R., Campos M.G.,
Cetina L., Bazan-Perkins B. Aerosolized polymerized type I collagen reduces airway
inflammation and remodelling in a guinea pig model of allergic asthma. Lung 188
(2): 97-105.
11. 2009 Bazán-Perkins B.,
Sánchez-Guerrero E., Campos M.G. Capacitative Ca2+ entry during Ca2+ undershoot
in bovine airway smooth muscle. Cellular Physiology and Biochemistry, 24:
161-166.
12. 2009 Bazán-Perkins B.,
Sánchez-Guerrero E., Vargas M., Martinez E., Ramos-Ramírez P., Alvarez-Santos
M., Hiriart G., Gaxiola M., Hernández-Pando R. β1-Integrins shedding in a
guinea pig model of chronic asthma with remodelled airways. Clinical and
Experimental Allergy, 39: 740-751.
13. 2009 Cetina L, Garcia-Arias A,
Candelaria M, Cantu D, Rivera L, Coronel J, Bazan-Perkins B, Flores V, Gonzalez
A, Duenas-Gonzalez A. Brachytherapy versus radical hysterectomy after external
beam chemoradiation: a non-randomized matched comparison in IB2-IIB cervical
cancer patients. World Journal of Surgical Oncology 7 (1): 19.
14. 2005 Montaño L.M., Bazán-Perkins B.
Resting calcium influx in airway smooth muscle. Canadian Journal of Physiology
and Pharmacology, 83 (8-9): 717-723.
15. 2005 Carbajal V., Vargas M.,
Flores-Soto E., Martínez-Cordero E., Bazán-Perkins B. y Montaño L.M. LTD4
induces hyperresponsiveness to histamine but not to carbachol in bovine airway
smooth muscle: Role of SR-ATPase Ca2+ pump and tyrosine kinase pathway.
American Journal of Physiology: Lung Cellular and Molecular Physiology 288:
L84-L92.
16. 2004 Bazán-Perkins B., Vargas M.H.,
Sánchez-Guerrero E., Chávez J. y L.M. Montaño. Spontaneous changes in guinea
pig respiratory pattern during barometric plethysmography: Role of
catecholamines and nitric oxide. Experimental Physiology, 85: 623-628.
17. 2003 Bazán-Perkins B., Flores E.,
Barajas-López C. y L.M. Montaño. Role of sarcoplasmic reticulum Ca2+ content in
Ca2+ entry of bovine airway smooth muscle cells. Naunyn-Schmiedeberg´s Archives
of Pharmacology 368: 277–283.
18. 2000 Bazán-Perkins B.,
Sánchez-Guerrero E., Carbajal V., Barajas-López C. y L.M. Montaño. Sarcoplasmic
reticulum Ca2+ depletion by caffeine and changes of [Ca2+]i during refilling in
bovine airway smooth muscle cells. Archives of Medical Research 31: 558-563.
19. 1998 Bazán-Perkins B., Carbajal V.,
Sommer B., Macías-Silva M., Gonzáles-Martínez M., Valenzuela F., Daniel E.E. y
L.M. Montaño. Involvement of different Ca2+ pools during the canine bronchial
sustained contraction in Ca2+ free medium: Lack of effect of PKC inhibition.
Naunyn-Schmiedeberg´s Archives of Pharmacology 358: 567-573.
20. 1997 Sommer B., Vargas M., Segura P.,
Bazán-Perkins B., Carbajal V., Chávez J., Gustin P. y L.M. Montaño. Effect of
different ozone concentrations on the neurogenic contraction and relaxation of
guinea pig airways. Fundamental and Clinical Pharmacology 11: 501-511.