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Biography

Dr. Prakasha Kempaiah

University of New Mexico School of Medicine, USA

Research Assistant Professor


Email: pkempaiah@salud.unm.edu


Qualification

2006 Ph.D., Institute of Human Genetics, Univ. of Goettingen, Germany

2000 M.Sc., Department of Biotechnology, Univ. of Agril Sciences,  India

1997 B.Sc., University of Agril Sciences, Bangalore, India



Publications (Selected)

  1. Kempaiah P, Chand HS, Kisiel W. Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues. Molecular Cancer. 2007 Mar 12;6:20. PMID:17352822.
  2. Kempaiah Pand Kisiel W. Human Tissue Factor Pathway Inhibitor-2 induces Caspase-mediated apoptosis in a human Fibrosarcoma cell line. Apoptosis. 2008 May; 13(5):702-15. PMID:18401718.
  3. Kempaiah P,Chand HS, Kisiel W. Human tissue factor pathway inhibitor-2 is internalized by cells and translocated to the nucleus by the importin system. Archives of Biochemistry and Biophysics. 2009 Feb;482(1-2):58-65. PMID: 19103149.
  4. Mohandas S, Kempaiah P, Choudhary M.L,  Murthy B.N.S, Gowda T.K.S. Somatic embryogenesis and Agrobacterium-mediated genetic transformation of geranium with chitinase-glucanase encoding genes. Indian Journal of Horticulture. 66(1), March 2009: 1-6.
  5. Kempaiah P, Danielson L, Barry M, Kisiel W. Comparative Effects of Aprotinin and Human Recombinant R24K KD1 on Temporal Renal Function in Long-Evans Rats. Journal of Pharmacology and Experimental Therapeutics. 2009 Dec;331(3):940-5. PMID:19776384.
  6. Awandare GA,Kempaiah P, Ochiel DO, Piazza P, Keller CC, Perkins DJ. Mechanisms of erythropoiesis inhibition by malarial pigment and malaria-induced proinflammatory mediators in an in vitro model. American Journal of Hematology. 2011 Feb;86(2):155-62. PMID:21264897.
  7. Ouma C, Davenport GC, Garcia S,Kempaiah P, Chaudhary A, Were T, Anyona SB, Raballah E, Konah SN, Hittner JB, Vulule JM, Ong'echa JM, Perkins DJ. Functional Haplotypes of Fc gamma (Fc) receptor (FcRIIA and FcRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children. Human Genetics. 2011 Aug 5. PMID:21818580.
  8. Ong'echa JM, Raballah EO,Kempaiah PM, Anyona SB, Were T, Davenport GC, Konah S, Vulule JM, Ouma C, Hittner JB, Perkins DJ. Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria. BMC Genetics. 2011 Aug 6;12(1):69. PMID:21819616.
  9. Anyona SB,Kempaiah P, Raballah E, Ouma C, Were T, Davenport GC, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ. Functional Promoter Haplotypes of Interleukin-18 Condition Susceptibility to Severe Malarial Anemia and Childhood Mortality. Infection and Immunity. 2011 Dec;79(12):4923-32. PMID:21969001.
  10. Perkins DJ, Were T, Davenport GC,Kempaiah P, Hittner JB, Ong'echa JM. Severe Malarial Anemia: Innate Immunity and Pathogenesis. Review article. International Journal of Biological Sciences. 2011; 7(9):1427-1442. PMID:22110393.
  11. Davidson LB, Nessar R,Kempaiah P, Perkins DJ, Byrd TF. Mycobacterium abscessus Glycopeptidolipid Prevents Respiratory Epithelial TLR2 Signaling as Measured by HβD2 Gene Expression and IL-8 Release. PLoS ONE. 2011; 6(12): e29148. PMID:22216191.
  12. Kempaiah P, Anyona SB, Raballah E, Davenport GC, Were T, Hittner JB, Ong'echa JM, Perkins DJ. (2012). Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality. Human Genetics. 2012 May 9. PMID:22570109.
  13. Anyona SB,Kempaiah P, Raballah E, Davenport GC, Were T, Konah SN, Vulule JM, Hittner JB, Gichuki CW, Ong'echa JM, Perkins DJ. Reduced Systemic Bicyclo-Prostaglandin-E2 and Cyclooxygenase-2 Gene Expression are associated with Inefficient Erythropoiesis and Enhanced Uptake of Monocytic Hemozoin in Children with Severe Malaria Anemia. 2012. American Journal of Hematology. 6 May 2012| DOI: 10.1002/ajh.23253. PMID:22730036
  14. Kempaiah P, Davidson LB, Perkins DJ, Byrd TF. Cystic fibrosis CFBE41o- cells contain TLR1 SNP 1602S and fail to respond to Mycobacterium abscessus (In Press, American Journal of Respiratory Cell and Molecular Biology)
  15. Rivas AL, Jankowski M, Piccinini R, Leitner G, Schwarz D, Anderson KL, Fair JM, Hoogesteijn AL, Wolter W, Chaffer M, Blum S, Were T, Konah SN,Kempaiah P, Ong’echa JM, Diesterbeck US, Pilla R, Czerny CP, Hittner JB, Hyman JM, Perkins DJ. Feedback-based, system-level properties of vertebrate-microbial interactions. (In Press, PLoS One)


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