Prof. Xi Huang

New York University, USA

Email: huang5do@gmail.com

Qualifications

1991 Ph.D., University of Paris VII, Toxicology & Pharmacology

1988 M.Sc., University of Paris VII, Toxicology & Pharmacology

1985 B.Sc., China Agricultural University, Agro-chemistry

Publications (selected)

1. Dai, J. S., Bosland, M., Bernhardt. G., Frenkel, K., and Huang, X*. “Role of hormone replacement therapy and iron in proliferation of breast epithelial cells with different estrogen and progesterone receptor status.” 2008, Breast, 17: 172-179.
2. Huang, X.* “Does iron have a role in breast cancer?” 2008, Lancet Oncol. 9: 803-807.
3. Pell, E., McCarthy, J., Seltmann, H., Huang, X., Mammone, T., Zouboulis, C. C., and Maes, D. “Identification of histamine receptors and reduction of squalene levels by an antihistamine in sebocytes.” J. Invest. Dermat. 2008, 128: 1280-1285.
4. Huang, X*., Fung, E.T., Yip, C., and Zeleniuch-Jacquotte, A. “Serum hepcidin is associated with soluble transferring receptor-1 but not ferritin in healthy post-menopausal women.” Blood Cells, Mol. Dis., 2008, 41: 265-269.
5. Jian, J.L., Pelle, E., and Huang, X.* “Iron and Menopause: Does increased iron play a role in menopause-related osteoporosis and skin aging?” Antioxid. Redox Signal., 2009, 11, 2939-2943. Article reported by Obesity, Fitness & Wellness Week, OBGYN & Reproduction Week, and Women's Health Weekly
6. Eckard, J., Dai, J., Wu, J., Jian, J.L., Yang, Q., Frenkel, K., Chen, H., Costa, M., and Huang, X.* “Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis.” Cancer Cell Int., 2010, 10: 28. Highly accessed on the Publisher’s website with more than 2,000 downloads since its publication in August 2010 (last checked March 18th 2011).
7. Jian, J.L., Pelle, E., Yang, Q., Pernodet, N., Maes, D., and Huang, X.* “Iron sensitizes keratinocytes and fibroblasts to UVA-mediated matrix metalloproteinase-1 through TNF-Z and ERK activation. Exp. Dermatol. 2011, 20: 249-254.
8. Jian J, Yang Q, Dai J, Eckard J, Axelrod D, Smith J, and Huang X.* “Effects of iron deficiency and iron overload on angiogenesis and oxidative stress-a potential dual role for iron in breast cancer. Free Rad. Biol. Med. 2011, 50: 841-847.
9. Yang, Q., Jian, J., Abramson, S.B., and Huang, X.* “Inhibitory effects of iron on bone morphogenetic protein-2-induced osteoblastogenesis.” J. Bone Min. Res. 2011, 26: 1188-1196.
10. Friedman, J., Cremer, M., Qurat ul-ain, J., Huang, X., Jian, J. Shah, S. and Katz S.D. “Oral contraceptive use, iron stores, and vascular endothelial function in healthy women.” Contraception, 2011, 84: 285-290.
11. Pelle, E., Jian, J., Declercq, L., Dong, K., Yang, Q, Pourzand, c., Pernodet, N., Maes, D., Yarosh, D.B., and Huang, X. “Protection against UVA- and iron-induced oxidative damage in normal human epidermal keratinocytes by the use of a caged-iron chelator.” Photodermatol, Photoimmunol & Photomed, 2011, 27: 231-235.
12. Jian, J., Yang, Q., and Huang, X.* Src regulates Tyr20 phosphorylation of transferrin receptor-1 and promotes breast cancer cell survival. J. Biol. Chem. 2011, 286, 35708-15.
13. Yang, Q., Jian, J., Katz, S.D., and Huang, X.* “Estrogen inhibits hepcidin through an estrogen responsive element half site.” Endocrinology, In Press.
14. Siegel, E.M., Patel, N., Lu, B., Lee, J.H., Nyitray, A.G., Huang, X., Villa, L.L., Franco, E.L., and Anna R. Giuliano, A.R. “Circulating Biomarkers of Iron Storage and Clearance of Incidence Human Papillomavirus Infection.” Cancer Epidemiol. Biomarl. Prev. In press.
15. Pelle, E., Maes, D., Huang, X., Frenkel, K., Pernodet, N., Yarosh, D.B., Zhang, Q. “Protection against UVB-induced oxidative stress in human skin cells and skin models by methionine sulfoxide reductase A.” Submitted to J. Cosmetic Sci.
16. Jian, J., Yang, Q., Shao, Y., Axelrod, D., Smith, J., Singh, B., Krauter, S., Chiriboga, L., Yang, Z., Li, J. and Huang, X.* “A link between premenopausal iron deficiency and breast cancer.” Submitted to Proc. Nat. Acad. Sci..
17. Pelle, E., Jian, J., Zhang, Q., Muizzuddin, N., Yang, Q., Dai, J., Maes, D., Pernodet, N., Yarosh, D.B., and Huang, X.* “Menopause increases iron storage protein ferritin in skin.” Submitted to Skin Pharmacol. Physiol..
18. Kennish, L., Attur, M., Oh, C., Krasnokutsky, S., Samuels, J., Huang, X. and Abramson, S.B. “Age- and HFE C282Y mutation-dependent ferritin increase as a predictor of knee osteoarthritis development.” Submitted to Arthritis Res..
19. Huang X., Xiao X. G., Shi J. N. et al. "General aspect of French agricultural education." In "Modern French Agriculture" (Eds. Sun B. Q., Cao M. Q), Beijing Agricultural University Press, Beijing, 1993, pp. 37-55.
20. Costa M., Zhuang Z. X., Huang X., Costentino S., Klein C. B., and Salnikow K. “Molecular mechanism of nickel carcinogenesis.” Sci. Total Environ. 1994, 148: 191-199.
21. Costa M., Costentino S., Salnikow K., Huang X., and Zhuang Z. X. "Molecular mechanism of nickel carcinogenesis." Environ. Health Perspect. 1994, 102: 127-130.
22. Huang X.* “Iron overload and its association with cancer risk in human: Evidence for iron as a carcinogenic metal.” Mutation Res. 2003, 533: 153-171.
23. Huang, X.*, Gordon, T., Rom, W. N., and Finkelman, R. B. “Interaction of iron and calcium minerals in coals and their roles in coal dust-induced occupational lung diseases.” In Medical Mineralogy and Geochemistry (Editors: Schoonen M., and Niati, N.), 2006, vol. 64: 153-172.
24. Huang, X.*, and Finkelman R. B. “Understanding the chemistry of macerals and minerals in coal dusts and its potential application for occupational lung disease prevention.” J. Toxicol. Environ. Health, Part B, 2008, 11: 45-67.
25. Huang, X*. “Iron, oxidative stress, and cell signaling in the pathogenesis of coal workers’ pneumoconiosis, silicosis, and asbestosis.” Am. J. Biomed. Sci., 2011, 3: 95-106.