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Biography

Dr. Jun Sun

Rush University, USA


Email: jun_sun@rush.edu


Qualifications

1998  Ph.D., Institute of Toxicology and Pharmacology, China

1992  M.Sc., Wuhan University, Wuhan, China

1989  B.Sc., Wuhan University, Wuhan, China


Publications (selected)

  1. Sheng-Ru Shiou, Yueyue Yu, Sangzi Chen, Elaine O Petrof, Jun Sun, and Erika C. Claud. Erythropoietin protects against necrotizing enterocolitis (NEC) and maintains intestinal epithelial barrier function through upregulation of tight junction protein. Journal of Biological Chemistry, 286 (14): 12123–12132, 2011.
  2. Isaac K. Sundar, Jae-Woong Hwang, Shaoping Wu, Jun Sun,and Irfan Rahman (co-senior-authored).Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation. Biochemical and Biophysical Research Communications. 406(1): 127-133, 2011.
  3. Xingyin Liu, Rong Lu, Shaoping Wu, Yinglin Xia, Yongguo Zhang, R. Balfour Sartor, Jun Sun. Wnt 2 inhibits bacterial-induced intestinal inflammation in epithelial cells. Inflammatory Bowel Diseases June 14 2011. doi: 10.1002/ibd.21788. [Epub ahead of print]PMID: 21674728.
  4. Xingyin Liu, Shaoping Wu, Yinglin Xia, Xi Li, and Jun Sun. Wingless homolog Wnt11 suppresses bacterial invasion and inflammation in intestinal epithelial cells. American Journal of Physiology-GI and Liver, Epub ahead of print, September 2011.
  5. Lactobacillus plantarum conditioned media reduces inflammation during infectious colitis. Michelle Taylor, Vandana Gambhir, Curtis Noordhof, Oliver Jones, Shu-Mei He, Erika C. Claud, Jun Sun, Sameh Basta, and Elaine O. Petrof. Journal of Immunology, Revision 2011.
  6. Rong Lu, Xingyin Liu, Shaoping Wu, Xinglin Xia, Yong-guo Zhang, Jun Sun. Consistent Activation of the beta-catenin pathway by the bacterial type III secretion effector protein AvrA in chronic infected mice. Submitted to Journal of Infectious Diseases, 2011.
  7. Yong-guo Zhang, Shaoping Wu, Yinglin Xia, Di Chen,  Elaine O. Petrof, Erika C. Claud, Wei Hsu, Jun Sun. Enteric bacteria exploit Axin1 in intestinal inflammation. Submitted to MCB 2011.
  8. Jun Sun. Vitamin D: Anti-inflammatory actions to prevent and treat disease. In: Vitamin D: Oxidation, Immunity & Aging.  Oxidative Stress and Disease series, edited by Lester Packer and Enrique Cadenas. Taylor & Francis Group, CRC Press. (book chapter 14), 2011, in press.
  9. Xingyin Liu, Rong Lu, Shaoping Wu, Jun Sun. Salmonella regulation of intestinal stem cells through the Wnt/beta-catenin pathway. FEBS Letter, 584: 911-916, 2010 March 5, 2010 (NIHMS171247, Publ.ID: FEBS33793)(Cover story).
  10. Shaoping Wu, Rong Lu, Yong-guo Zhang, and Jun Sun: Chronic Salmonella infected mouse model. Journal of Visualized Experiments (JoVE), http://www.jove.com/index/details.stp?id=1947,doi: 10.3791/1947. March. 2010.
  11. Shaoping Wu, Zhongde Ye, Xingyin Liu, Yun Zhao, Yinglin Xia, Andrew Steiner, Elaine O. Petrof, Erika C. Claud, Jun Sun. “Salmonella  Typhimurium infection increases p53 acetylation in intestinal epithelial cells.” American Journal of Physiology -GI and Liver, 298: G784-G794, 2010.
  12. Rong Lu, Shaoping Wu, Xingyin Liu, Xinglin Xia, Yong-guo Zhang, Jun Sun. Chronic effects of a Salmonella type III secretion effector protein AvrA in vivo. PLoS One, PMID: 20463922 http://dx.plos.org/10.1371/journal.pone.0010505. May 5 2010.
  13. Shaoping Wu, Anne P Liao, Yinglin Xia, Yan Chun Li, Jian-Dong Li, Balfour Sartor, and Jun Sun. Vitamin D receptor negatively regulates intestinal epithelial NF-kappaB activity with bacterial stimulation. Am. J. of Pathology. 2010,177: 686-697. PMID: 20566739. (Research Highlight, Nature Reviews Gastroenterology and Hepatology 7, 532 (October 2010) | doi:10.1038/nrgastro.2010.142).
  14. Jun Ma, Yong-guo Zhang, Jun Sun. Inflammatory cytokine tumor necrosis factor stimulation modulates the expressions of Salmonella typhimurium effector proteins. Journal of Inflammation. 2010, 7: 42. doi:10.1186/1476-9255-7-42
  15. Xingyin Liu, Rong Lu, Yinglin Xia, Jun Sun. Global analysis of the eukaryotic signaling pathways regulated by Salmonella typhimurium in intestinal infection in vivo. BMC Genomics. 2010,11: 722 (Highly accessed article).
  16. Xingyin Liu, Rong Lu, Yinglin Xia, Shaoping Wu, Jun Sun. Eukaryotic signaling pathways targeted by Salmonella effector protein AvrA in intestinal infection in vivo. BMC Microbiology. 2010. 10: 326(Highly accessed article).