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Biography

Prof. Ramesh C. Gupta

Toxicology Department,

Murray State University, USA

Professor


Email: rgupta@murraystate.edu


Qualifications

1977 Ph.D., Punjab Agricultural University, Veterinary Sciences

1973 M.Sc., GB Pant University of Agriculture and Technology, Veterinary Medicine

1971 DVM, GB Pant University of Agriculture and Technology, Veterinary Medicine


Publications (Selected)

  1. Litchfield, H., Gupta, R.C., Doss, R.B., Bland, S.D., and Canerdy, T.D. Safety evaluation of permethrin and indoxacarb in dogs topically exposed to Activyl tick plus. J. Vet. Sci. Technol. 6(2): 1-9 (2015).
  2. May, K., Gupta, R.C., Miller, J., Goad, J.T., Lasher, M.A., Conway, R., Canerdy, T.D., Kalidindi, S.R. Therapeutic efficacy and safety evaluation of a novel chromium supplement (Crominex+3) in moderately arthritic horses. J. Vet. Sci. Res. 2(1):1-10.
  3. Nichols, H., Gupta, R.C., Doss, R.B., Bland, S.D., Canerdy, T.D., and Zieren, J.: Residue of fipronil, s-methoprene, and amitraz in dog blood and in gloves from topical application Certifect application: Toxicity and safety considerations. J. Vet. Sci. Res. 1:1-9 (2-14).
  4. Bland, S.D., Gupta, R.C., Lasher, M.A., Canerdy, T.D.: Safety assessment of etofenprox, s-methoprene, and piperonyl butoxide in dogs topically exposed to Bio Spot defense. J. Vet. Sci. Technol. 4(6): 1-7 (2013).
  5. Lawley, S., Gupta, R.C., Goad, J.T., Canerdy, T.D., Kalidindi, S.R.: Anti-inflammatory and anti-arthritic efficacy and safety of purified Shilajit in moderately arthritic dogs. J. Vet. Sci. Anim. Husb. 1(3):1-6 (2013).
  6. Fleck, A., Gupta, R.C., Goad, J.T., Lasher, M.A., Canerdy, T.D.: Anti-arthritic efficacy and safety of chrominex 3+ (trivalent chromium, Phyllanthus emblica, extract, and Shilajit) in moderately arthritic dogs. . J. Vet. Sci. Anim. Husb. 1(4):1-6 (2014).
  7. Milatovic, D., Gupta, R.C., Yu, Y, Zaja-Milatovic, S., and Aschner, M.: Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury. Toxicol. Appl. Pharmacol. Special Issue “Environmental Chemicals and Neurotoxicity”, 256:219-226 (2012).
  8. Gupta, R.C., Canerdy, T.D., Lidley, J., Konemann, M., Minniear, J., Carroll, B.A., Hendrick, C., Goad, J.T., Rohde, K., Doss, R.B., Bagchi, M., and Bagchi, D.: Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate. J. Anim. Physiol. Anim. Nutri. 96:770-777 (2011).
  9. Marone, P.A., Lau, FC., Gupta, R.C., Bagchi, M., and Bagchi, D.: Safety and toxicological evaluation of undenatured type II collagen. Toxicol. Mechan. Methods. 20:175-189 (2010).
  10. Marone, P.A., Yasmin, T., Gupta, R.C., and Bagchi, M.: Safety and toxicological evaluation of AlgalCal(R) (AC), a novel plant-based calcium supplement. Toxicol. Mechan. Methods. 20: 334--344 (2010).
  11. Finkelstein, Y., Milatovic, D., Lazarovici, P., Ophir, A., Richter, E.D., Aschner, M., Lecht, S., Marcinkiewicz, C., Lelkis, P.I., Zaja-Milatovic, S., Gupta, R.C., Brodsky, B., Rosengarten, A., Proscura, E., Shapira, E., and Wormser, U.: Peaceful use of disastrous neurotoxicants. Neurotoxicology,  3451-3462 (2010).
  12. Milatovic, D., Zaja-Milatovic, S., Gupta, R.C., Yu, Y., and Aschner, M.: Oxidative damage and neurodegeneration in manganese-induced neurotoxicity. Toxicol. Appl. Pharmacol. Special Issue “Toxicants and Neurodegenerative Diseases”, 240(2): 124-131 (2009).
  13. Zaja-Milatovic, S., Gupta, R.C., Aschner, M., and Milatovic, D.: Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist. Toxicol. Appl. Pharmacol. Special Issue “Toxicants and Neurodegenerative Diseases”, 240 (2): 219-225 (2009).
  14. Gupta, R.C., Canerdy, T.D., Skaggs, P., Stocker, A, Zyrkowski, G., Burke, R., Wegford, K., Goad, J.T., Barnett, D., DeWees, W., Bagchi, M., and Bagchi, D.: Therapeutic efficacy of undenatured type-II collagen (UC-II) in comparison to glucosamine and chondroitin in arthritic horses. J. Vet. Pharmacol. 32: 577-584 (2009).
  15. Zaja-Milatovic, S., Gupta, R.C., Aschner, M., Montine, T.J., and Milatovic, D.: Pharmacologic suppression of oxidative damage and dendritic degeneration following kainic acid-induced excitotoxicity in mouse cerebrum. Neurotoxicology. 29(4): 621-627 (2008).
  16. Gupta, R.C. and Dekundy, A.: Donepezil or rivastigmine induced acetylcholinesterase Inactivation is not modulated by neramexane in rat brain. Drug Dev. Res. 68:253-260 (2007).
  17. Gupta, R.C., Milatovic, S., Dettbarn, W-D., Aschner, M. and Milatovic, D.: Neuronal oxidative injury and dendritic damage induced by carbofuran: Protection by memantine. Toxicol. Appl. Pharmacol., Special Issue “Anticholinesterases” 219 (2-3): 97-105 (2007).
  18. Liu, J., Gupta, R.C., Goad, J.T., Karanth, S., and Pope, C.N.: Modulation of parathion Toxicity by glucose feeding: Is nitric oxide involved? Toxicol. Appl. Pharmacol. Special Issue  “Anticholinesterases” 219 (2-3): 106- 113 (2007).
  19. D’Altilio, M., Peal, A., Alvey, M., Simms, C., Curtsinger, A. Gupta, R.C., Canerdy, T.D., Goad, J.T., Bagchi, M., and Bagchi, D.: Therapeutic efficacy and safety of undenatured type II collagen singly or in combination with glucosamine and chondroitin in arthritic dogs. Toxicol. Mechan. Methods. 17: 189- 196 (2007).
  20. Jiang, G.C.-T., Tidwell, K., McLaughlin, B.A., Cai, J., Gupta, R.C., Milatovic, D., Nass, R., And Aschner, M.: Neurotoxic potential of depleted uranium- Effects in primary cortical neuron cultures and in Caenorhabditis elegans. Toxicol. Sci.: 553-565 (2007).
  21. Milatovic, D., Yin, Z., Gupta, R.C., Sidoryk, M., Albrecht, J., Aschner, J.L., and Aschner, M.: Manganese induces oxidative impairment in cultured rat astrocytes. Toxicol. Sci. 98: 198-205 (2007).
  22. Peal, A., D’Altilio, M., Simms, C., Alvey, M., Gupta, R.C., Goad, J.T., Canerdy, T.D., Bagchi, M., and Bagchi, D.: Therapeutic efficacy and safety of undenatured type-II collagen (UC-II) alone or in combination with (-)-hydroxycitric acid and chromemate in arthritic dogs. J. Vet. Pharmacol. Therap. 30: 275-278 (2007).
  23. Yang, M.S., Tse, W.K.F., Yu, L.C., Li, K.M., Mak, N.K., and Gupta, R.C.: Energy and redox states in the C6 glioma cells following acute exposure to Zn, Se+4 and Se+6 and the correlation with apoptosis. Toxicol. Mechan. Methods. 16: 13-19 (2006).
  24. Gupta, R.C., and Dekundy, A.: Memantine does not influence AChE inhibition in rat brain by donepezil or rivastigmine but does with DFP and metrifonate in in vivo studies. Drug Dev. Res. 64: 71-81 (2005).
  25. DeParle, L.A., Gupta, R.C., Canerdy, T.D., Goad, J.T., D’Altilio, M., Bagchi, M., and Bagchi, D.: Efficacy and safety of glycosylated undenatured type-II collagen (UC-II)) in therapy of arthritic dogs. J. Vet. Pharmacol. Therap. 28: 385-390 (2005).