Dr. Sukhotnik Igor

Technion- Israel Institute of Technology

Bnai Zion Medical Center, Israel

E-mail: igor-dr@internet-zahav.net

Qualifications

1979-1985  M.D., University of Medicine, Chernovtsy, Ukraine

Publications (Selected)

1. Sukhotnik I, Mogilner JG, Ben Lulu S, Bashenko Y, Shaoul R,   Chemodanov E, Coran AG. Nutritional supplementation with transforming growth  factor-beta  (TGF-β) inhibits  intestinal adaptation after massive small bowel resection in a rat. Ped Surg International 2011; 27:211-216.
2. Sukhotnik I, Slijper N, Chemodanov E, Bashenko Y, Shaoul R, Coran AG, Mogilner JG. Parenteral omega-3 fatty acids (Omegaven) modulate intestinal recovery following intestinal ischemia-reperfusion in a rat. J Pediatr Surg 2011, 46: 1353-1360.
3. Sukhotnik I, Shamir R, Bashenko Y, Mogilner KG,  Chemodanov E, Shaoul R, Coran AG, Shehadeh N. Effect of oral insulin on diabetes-induced intestinal mucosal growth in a rat. Dig Dis Sci 2011; 56: 2566-2570.
4. Shaoul R, Mogilner J, Coran A, Chemodanov E, Sukhotnik I., Nutritional supplementation with transforming growth factor-beta (TGF-β) affects enterocyte turnover in correlation with TGF-β receptor expression after massive small bowel resection in a rat.  Gastroenterology, 2010, 138 (5 Supplement 1), p.S-705.
5. Sukhotnik  I,  Kuscuoglu  U,  Altindag  B,  Tao  GZ,  Lehwald  N,  Sylvester  KG.  Intestinal involvement during 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced chronic liver injury in a mouse model. J Pediatr Surg 2011; 46:1495-1502.
6. Ben  Lulu  S,  Coran  AG,  Shehadeh  N,  Shamir  R,  Mogilner  JG,  Sukhotnik  I.  Oral insulin stimulates intestinal epithelial cell turnover following massive small bowel resection in a rat and a cell culture model. Pediatr Surg Int 2012; 28:179-187.
7. Sukhotnik I, Razon H, Pollak Y, Hayari L, Bejar J, Mogilner JG, Sylvester KG. Effect of alpha- naphthylisothiocyanate-induced liver injury on intestinal adaptation in a rat model of short bowel 13 syndrome. Pediatr Surg Int 2012; 28:161-169.
8. Koppelmann T, Pollak Y, Mogilner J, Bejar J, Coran AG, Sukhotnik I. Dietary L-arginine supplementation   reduces methotrexate-induced intestinal mucosal injury     in rat. BMC Gastroenterology 2012; 30; 12:41.
9. Koppelmann T, Pollak Y, Mogilner J, Bejar J, Coran AG, Sukhotnik I. Reversal of severe MTX- induced intestinal damage using enteral Omega-3 fatty acids. Br J Nutr 2012; 28:1-10.
10. Sukhotnik I, Mogilner J, Pollak Y , Blumenfeld S, Bejar J, Coran AG. Platelet-derived growth factor-alpha (PDGF-α) stimulates intestinal epithelial cell turnover after massive small bowel resection in a rat. American Journal of Physiology: GI & Liver 2012; 302:G1274-1281.
11. Sukhotnik I, Ben Lulu S,   Pollak Y, Bejar J, Coran AG, Mogilner JG. Transforming growth factor-beta (TGF-β) affects enterocyte turnover in correlation with TGF-β receptor expression after massive small bowel resection in a rat. J Pediatr Gastroenterol Nutr (JPGN) 2012; 55:721-727.
12. Ben-Lulu S, Pollak Y, Mogilner J, Bejar J, Coran AG, Sukhotnik I.  Dietary transforming growth factor-beta 2 (TGF-β2) supplementation reduces methotrexate-induced intestinal mucosal injury in a rat. PLoS ONE 2012; 7(9):e45221.
13. Sukhotnik I, Nativ O, Roitburt A, Bejar D, Coran AG, Mogilner JG, Nativ O. Methotrexate induces germ cell apoptosis and impairs spermatogenesis in a rat. Pediatr Surg Int 2013; 29:179-184.
14. Hadjittofi C, Coran AG, Mogilner JG, Pollak Y, Matter I, Sukhotnik I. Dietary supplementation with vitamin D stimulates intestinal epithelial cell turnover after massive small bowel resection in rats. Pediatr Surg Int 2013; 29:41-50.
15. Sohotnik R, Nativ O, Abbasi A, Awad H, Frajewicki V, Bishara B, Sukhotnik I, Armaly Z, Aronson D, Heyman SN, Nativ O, Abassi Z. Phosphodiesterase-5 inhibition attenuates early renal ischemia-reperfusion-induced acute kidney injury: assessment by quantitative measurement of urinary NGAL and KIM-1. Am J Physiol Renal Physiol 2013; 304: F1099-1104.
16. Sukhotnik I,  Swaid F, , Matter I, Berkowitz D, Hadjittofi C, Pollak Y, Lavy A. Dietary glutamine supplementation prevents mucosal injury and modulates intestinal epithelial restitution following acetic acid induced intestinal injury in rats. Nutr Metab (Lond), 2013; 10: 53-60.
17. Sukhotnik I, Roitburt A, Pollak Y, Dorfman T, Matter I, Mogilner JG, Bejar J, Coran AG. Wnt/β-catenin signaling cascade down-regulation following massive small bowel resection in a rat.  Pediatr Surg Int, 2014; 30:173-180.
18. Sukhotnik I,  Haj B, Shaoul R, Pollak Y, Coran AG, Bitterman A, Matter I. Effect of ozone on intestinal recovery following intestinal ischemia-reperfusion injury in a rat. Pediatr Surg Int., 2014; 30:181-188.
19. Sukhotnik I, Pollak Y, Coran AG, Pilatov J, Bejar J, Mogilner JG, Berkowitz D. Glutamine attenuates the inhibitory effect of methotrexate on TLR signaling during intestinal chemotherapy-induced mucositis in a rat. Nutr Metab (Lond), 2014; 17; 11: 17-24.
20. Sukhotnik I, Geyer T, Pollak Y, Mogilner JG, Coran AG, Berkowitz D., The role of Wnt/β-catenin signaling in enterocyte turnover during methotrexate-induced intestinal mucositis in a rat. PLoS One 2014; 9(11):e110675. doi: 10.1371.
21. Sukhotnik I, Starikov A, Coran AG, Pollak Y, Sohotnik R, Shaoul R. Effect of ozone on intestinal      epithelial homeostasis in a rat.  Rambam Maimonides Med J, 2015; 6(1): e 0006.
22. Somri  M,  Coran  AG,  Mattar  I,  Teszler  C,  Shaoul  R,  Tomkins  O,  Tome  R,  Mogilner  JG, Sukhotnik I, Gaitini L. The postoperative occurrence of cardio-respiratory adverse events in small infants undergoing gastrointestinal surgery: a prospective comparison of general anesthesia and combined spinal-epidural anesthesia. Pediatr Surg Int 2011, 27:1173-1178.
23. Somri M, Coran AG, Hadjittofi C, Parisinos CA, Mogilner JG, Sukhotnik I, Gaitini  L, Tome R, Matter I. Improved outcomes in paediatric anaesthesia: contributing factors. Pediatr Surg Int.2012;28:553-561.
24. Abassi Z, Shalabi A, Sohotnik R, Nativ O, Awad H, Bishara B, Frajewicki V, Sukhotnik I, Abbasi A, Nativ O. Urinary NGAL and KIM-1: Biomarkers for assessment of acute ischemic kidneyinjury following nephron sparing surgery. J Urol. , 2012; 18. doi:pii: S0022-5347(12)05257-3.
25. Steiner Z, Natan OB, Sukhotnik I, Coran AG, Keren G. Does Staphylococcus aureus nasal carriage require eradication prior to elective ambulatory surgery in children? Pediatr. Surg. Int., 2014; 30: 521-525.