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Biography

Dr. Yohichi Kumaki

Utah State University, USA


E-mail: yohichi.kumaki@usu.edu


Qualification


1995 Ph.D., Gunma University, Japan

1985 M.D., Second Military Medical University, China


Publications (selected)

  1. Kumaki, Y., Salazar, A. M., Wandersee, M.K., Morrey, J.D., Barnard, D.L. Prophylactic and therapeutic intranasal administration with an immunomodulator, Hiltonol® (Poly IC:LC), in a lethal SARS-CoV-infected BALB/c mouse model (in preparation).
  2. Smith, A.J., Vest, Z.G., Wandersee, M.K., Kumaki, Y., Bailey, K.W., Salazar, A.M., Barnard, D.L. The effectiveness of polyinosinic-polycytidylic acid [poly(I:C)] stabilized by lysine and carboxymethylcellulose (poly-ICLC) against a highly pathogenic avian influenza infection using a murine model (in preparation).
  3. Kumaki, Y., Day, C.W., Smee, D.F., Morrey, J.D., Barnard, D.L. In vitro and in vivo efficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1, seasonal, and pandemic H1N1 virus infections. Antiviral Res., 2011: 92: 329-340.
  4. Barnard, D.L. and Kumaki, Y. Recent developments in anti-severe acute respiratory syndrome coronavirus chemotherapy. Future Virol., 2011: 6: 615-631
  5. Kumaki, Y., Wandersee, M.K., Smith, A.J., Zhou, Y., Simmons, G., Nelson, N.M., Bailey, K.W., Vest, Z.G., Li, J.K., Smee, D.F., Barnard, D.L. Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin. Antiviral Res., 2011: 90: 22-32.
  6. Kumaki, Y., Ennis, J., Rahbar, R., Turner, J.D., Wandersee, M.K., Bailey, K.W., Smith, A.J., Vest, Z.G., Madsen, J.R., Li, J.K., Barnard, D.L. Single-dose intranasal administration with mDEF201 (adenovirus vectored mouse interferon-alpha) confers protection from mortality in a lethal SARS-CoV BALB/c mouse model. Antiviral Res., 2011: 89: 75-82.
  7. Kumaki, Y., Kumaki, I., Guo, X.M., Shang, W.L., Koyama, T., Okamura, A., Shiba, Y., Mukaiyama, T., Sasaki, N., Kodama, M. Long-term culture of primary porcine mature hepatocytes in the medium supplemented with ascorbic acid 2-phosphate. Natural Sci., 2010, 2, 1264-1273.
  8. Kumaki, Y., Day, C.W., Wandersee, M.K., Madsen, J.R., Woolcott, J.D., Hoopes, J.D., Bailey, K.W., Wong, M.H., Smee, D.F., Barnard, D.L. Induction of interferon gamma inducible protein 10 by SARS-CoV infection, interferon alfacon 1 and interferon inducer in human bronchial epithelial Calu-3 cells and BALB/c mice. Antivir. Chem. Chemother., 2010: 20: 169-77.
  9. Day, C.W., Baric, R., Cai, S.X., Frieman, M., Kumaki, Y., Morrey, J.D., Smee, D.F., Barnard, D.L. A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo. Virology, 2009: 395: 210-220.
  10. Barnard, D.L. and Kumaki, Y. Development in the search for small molecule inhibitors for treatment of severe acute respiratory syndrome coronavirus. Antiviral Research: Strategies in Antiviral Drug Discovery Edited by R. L. LaFemina 2009 ASM Press, Washington, DC., Chapter 12, 209-222.
  11. Kumaki, Y., Day, C.W., Wandersee, M.K., Schow, B.P., Madsen, J.S., Grant, D., Roth, J.P., Smee, D.F., Blatt, L.M., Barnard, D.L. Interferon alfacon 1 inhibits SARS-CoV infection in human bronchial epithelial Calu-3 cells. Biochem. Biophys. Res. Commun., 2008, 371, 110-113.
  12. Won-Tak Choi, Yohichi Kumaki, I. M. Krishna Kumar, Jing An, Douglas D. Richman, Joseph G. Sodroski, Ziwei Huang.  Basic and Translational Research of Chemokine Ligands and Receptors and Development of Novel Therapeutics.  Drug Discovery Research New Frontiers in the Post-Genomic Era.  Nov. 2006, DOI: 10.1002/9780470131862.ch12.
  13. Kumaki, I., Yang, D., Koibuchi, N., Takayama, K. Neuronal expression of nuclear transcription factor MafG in the rat medulla oblongata after baroreceptor stimulation. Life Sci., 2006, 78, 1760-1766.
  14. Yang, D-W., Shuda, M., Kaji, H. Inhibition of human T-cell leukemia virus type I by the short oligoguanylic acids in vitro. Mater. Sci. Eng. C., 2004, 24, 887-892.
  15. Yang, D-W., Koyama, T., Okamura, A., Shiba, Y., Kodama, M. Ascorbic acid 2-phosphate enhances the albumin mRNA expression and secretion of porcine hepatocytes. Mater. Sci. Eng. C., 2004, 24, 323-327.
  16. Yang, D-W., Fujii, N., Takata, T., Shimo-Oka, T., Tajima, S., Tanaka, Y., Saito, T. Expression of human D-beta aspartate in the lens-derived cell lines. Mol. Vision, 2003, 9, 200-204.