Prof. David Allen Hunt
The College of New Jersey, USA
Email: hunt@tcnj.edu
Qualifications
1979 Ph.D., Duke University, Organic Chemistry
1975 M.S., Marshall University, Organic Chemistry
1973 B.S., Marshall University, Chemistry
Publications (Selected)
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Nayak, S.; Fiaschi, M.; King, D.; Tabakin, E. R.; Wood,
L.; Hunt, D.A. “Development of small molecular proteasome inhibitors using
a Caenorhabditis elegans screen” Int. Med.
Chem. vol. 2014, Article ID 237286, 14 pages, 2014.
doi:10.1155/2014/237286.
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Cherney,
E.; Macor, J.; Papanagapolous, C.; Hunt, D.A. “Tandem cyclization reactions of
electron rich arylethylamino acid amides. An entry to the
dihydroimidazoisoquinolin-3(2H)-one ring system,” Tetrahedron Lett. 2014, 55,
4837-4839.
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Geherty, M.; Melnyk, J.; Chomsky, K.; Hunt, D.A.
“Halogen-metal exchange reactions of bromoaryl-substituted β-lactams, Tetrahedron Lett. 2013, 54, 4934-4936.
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Simpkins, C.; Hunt, D.A. “The Michael addition of
1,2-cyclohexanedione to -nitro- styrenes (I).
The synthesis of 3-aryl-5,6-dihydrobenzofuran-7(4H)-ones,” Tetrahedron Lett. 2013, 54, 3373-3375.
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Weinstein, J.D.; Gonzalez, E.R.; Egleton, R.D.; Hunt,
D.A. “The 10-patient screening protocol: a paradigm shift for evaluating
pharmacotherapy for Alzheimer’s disease,” The
Consultant Pharmacist 2013, 28,
443-454.
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Bradley, L.M.; Nardone, M.J.; Hunt, D.A. “An
expedient in situ preparation of
symmetrical 1,4-dibenzylpiperazines from benzyl bromides and 2-bromoethylamine
hydrobromide,” Tetrahedron Lett. 2010, 51, 5613-5614.
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Bradley, L.M.; Collins, C.G.; Tabakin,
E.R.; Hunt, D.A. “Expedient preparations of
4,6-Dihalo-3-arylisobenzofuran-1(3H)-ones from 3,5-dihalo-N-ethylbenzamides,” Org.
Prep. Proced. Int. 2010, 42, 187-190.
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Deifel, N.P.; Cherney, E.; Hunt,
D.A.; Chan, B.C. “1-Methyl-2H-1,3-benzoxazine-2,4(1H)dione” Acta Cryst. 2010, E66, o665.
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Hunt,
D.A. “Solvent and
electronic effects on kinetics of cyclization of thermolabile aryllithium
reagents. A comparison between
1-bromo-2-(2-bromoethyl)benzene and
4,5-dimethoxy-1-bromo-2-(2-bromoethyl)benzene,” Org. Commun. 2009, 2, 60-65.
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Clarke A. J.; Hunt, D.A. “-Nitrostyrenes as electrophiles in Parham Cyclization chemistry. Reaction with o-lithiobenzonitrile,” Tetrahedron Lett. 2009, 50, 2949-2951.
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Hunt,
D.A. "An improved method for the preparation of 2-(2-aminoaryl)-2-oxazolines
from substituted isatoic anhydrides and 2-chloroethylamine hydrochloride," Org. Prep. Proced. Int. 2007, 39, 93-96.
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Hunt,
D.A. “Condensation of tricyclic pyrrolopyridine diones and an isoindoline dione
with methylnitronate anion,” Heterocyclic
Commun. 2006, 12, 403-406.
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Demas,
M.; Javadi, G.J.; Bradley, L.M.; Hunt, D.A. “Metalation of a 3,5-dichloro tertiary
benzamide. An unusual regioselectivity observation,” J. Org. Chem. 2000, 65, 7201-7202.
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Henegar
K.E.; Hunt, D.A. “Expedient preparations of 2-trifluoromethylindole and its
N-methyl derivative,” Heterocycles 1996, 43,
1471-1475.
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Hunt,
D.A. “2-Arylpyrroles: a new class of insecticide. Structure, activity, and mode of action,” Pest.
Sci. 1996, 47, 201-202.
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Barnes,
K.D.; Hu, Y.; Hunt, D.A. “Electrophilic fluorination of a highly functionalized
pyrrole,” Syn. Commun. 1994, 24, 1749-1755.
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Treacy,
M.; Miller, T.; Black, B.; Gard, I.; Hunt, D.A.; Hollingworth, R.M. “Uncoupling
activity and pesticidal properties of pyrroles,” Biochem. Soc. Trans. 1994, 22, 244-247.
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Hunt,
D.A. “Michael addition of organolithium compounds. A review,” Org. Prep. Proced. Int. 1989, 21, 705-749.
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Hunt,
D.A. “An efficient preparation of 1,2-dihydrocyclobuta-[a]-naphthalene,” Org. Prep. Proced. Int. 1989, 21, 360-363.
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Hunt,
D.A.; Quante, J.M.; Tyson, R.L.; Dasher, L.W. “The preparation and utilization
of corticosteroidal -allylpalladium complexes. A novel entry to 6-,-carboxymethylcortisol,” J. Org. Chem. 1984, 49, 5262-5264.
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Bradsher,
C.K.; Hunt, D.A. “A novel synthesis of benzo[1,2:4,5] dicyclobutane via a dual Parham Cyclialkylation,” J.
Org. Chem. 1981, 46, 4608-4610.
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Bradsher
C.K.; Hunt, D.A. “Schiff bases as external and internal electrophiles in
reactions of functionalized aryllithium reagents. A new route to isoindoline
derivatives and 1,2,3,4-tetrahydroisoquinolines,” J. Org. Chem. 1981, 46, 327-330.
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Bradsher,
C.K.; Hunt, D.A. “A new route to the acridizinium ion,” J. Org. Chem. 1980, 45, 4248-4250.
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Reames, D.C.; Hunt, D.A.; Bradsher, C.K. “A one-pot
synthesis of some dibenzosuberones via the Parham Cycliacylation reaction,” Synthesis 1980, 454-456.
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Hunt,
D.A. “A study of the reaction of functionalized aryllithium reagents with
internal and external electrophiles. A
pathway to the synthesis of heterocyclic and carbocyclic systems,” Diss.
Abstr. Int. B. 1980, 40, 3741.
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Bradsher
C.K.; Hunt, D.A. “An efficient synthesis of 4,5-dimethoxybenzocyclobutane via the Parham Cyclialkylation reaction,” Org. Prep. Proced. Int. 1978, 10, 267-272.
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Parham,
W.E.; Bradsher, C.K.; Hunt, D.A. “Reaction of aryllithium reagents with nitriles. Synthesis of 1-substituted-3,4-dihydroisoquinolines,” J. Org. Chem. 1978, 43, 1606-1607.
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Douglass,
J.E.; Hunt, D.A. “Synthesis of quinolizinones by the condensation of ylidenemalononitriles
with quinoline-1-oxide,” J. Org. Chem. 1977, 42,
3974-3976.