Dr. Paula Isabel da Silva Moreira
University of Coimbra, Portugal

Email: pismoreira@gmail.com

Qualifications
2007  Ph.D., University of Coimbra, Biomedical Sciences
2002  M.S, University of Coimbra, Cell Biology
1998  B.S, University of Coimbra, Biology

1. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. Alzheimer’sdisease: diverse aspects of mitochondrial malfunctioning. Int J Clin Exp Pathol. 2010;3:570-581.
2. Moreira PI, Santos RX, Zhu X, Lee HG, Smith MA, Casadesus G, Perry G. Autophagy inAlzheimer’s disease. Expert Rev Neurother. 2010;10:1209-1218.
3. Santos RX, Cardoso S, Correia S, Carvalho C, Santos MS, Moreira PI. Targetingautophagy in the brain: a promising approach? Cent Nerv Syst Agents Med Chem.2010;10:158-168.
4. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondria: the missinglink between preconditioning and neuroprotection. J Alzheimers Dis. 2010;20:S475-485.
5. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. A synergisticdysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer’s disease. JAlzheimers Dis. 2010;20:S401-412.
6. Correia SC, Santos RX, Cardoso S, Carvalho C, Santos MS, Oliveira CR, Moreira PI.
7. Effects of estrogen in the brain: is it a neuroprotective agent in Alzheimer’s disease? Curr AgingSci. 2010;3:113-126.
8. Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G. Detection and localizationof markers of oxidative stress by in situ methods: application in the study of Alzheimer disease.Methods Mol Biol. 2010;610:419-434.
9. Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger ofAlzheimer’s disease pathophysiology. Biochim Biophys Acta. 2010;1802:2-10.
10. Moreira PI, Zhu X, Wang X, Lee HG, Nunomura A, Petersen RB, Perry G, Smith MA.
11. Mitochondria: a therapeutic target in neurodegeneration. Biochim Biophys Acta. 2010;1802:212-220.
12. Correia SC, Moreira PI. Hypoxia-inducible factor 1: a new hope to counteractneurodegeneration? J Neurochem. 2010;112:1-12.
13. Cardoso SM, Pereira CF, Moreira PI, Arduino DM, Esteves AR, Oliveira CR. Mitochondrialcontrol of autophagic lysosomal pathway in Alzheimer's disease. Exp Neurol. 2010;223-294-298.
14. Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA,Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. J Alzheimers Dis. 2009;18:483-507.
15. Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA,Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia.J Bioenerg Biomembr. 2009;41:433-440.
16. Perry G, Moreira PI, Siedlak SL, Nunomura A, Zhu X, Smith MA. Natural oxidant balance inParkinson disease. Arch Neurol. 2009;66:1445.
17. Moreira PI, Cardoso SM, Pereira CM, Santos MS, Oliveira CR. Mitochondria as aTherapeutic Target in Alzheimer's Disease and Diabetes. CNS Neurol Disord Drug Targets.2009;8:492-511.
18. Carvalho C, Santos RX, Cardoso S, Correia S, Oliveira PJ, Santos MS, Moreira PI.
19. Doxorubicin: the Good, the Bad and the Ugly Effect. Curr Med Chem. 2009;16:3267-3285.
20. Moreira PI, Duarte AI, Santos MS, Rego AC, Oliveira CR. An integrative view of the role ofoxidative stress, mitochondria and insulin in Alzheimer's disease. J Alzheimers Dis.2009;16:741-761.