Advances in Bioscience and Biotechnology

Vol.4 No.5(2013), Paper ID 32272, 11 pages

DOI:10.4236/abb.2013.45086

 

Construction, expression and binding specificity of bispecific CD3 × VEGFR-2 and CD3 × NCAM antibodies in the single chain and diabody format

 

Anke Kopacek, Thomas Böldicke, Sarah Lergenmüller, Frank Berthold, Markus Jensen, Peter P. Müller, Ludger Grosse-Hovest

 

Helmholtz Center for Infection Research, Department of Molecular Biotechnology, Braunschweig, Germany
Helmholtz Center for Infection Research, Department of Molecular Biotechnology, Braunschweig, Germany
Helmholtz Center for Infection Research, Department of Molecular Biotechnology, Braunschweig, Germany
Department of Pediatric Oncology and Hematology, University of Cologne, University Hospital Cologne, Cologne, Germany
Department of Pediatric Oncology and Hematology, University of Cologne, University Hospital Cologne, Cologne, Germany
Helmholtz Center for Infection Research, Department of Molecular Biotechnology, Braunschweig, Germany
Institute for Cell Biology, Department of Immunology, Eberhard Karls University, Tübingen, Germany

 

Copyright © 2013 Anke Kopacek, Thomas Böldicke, Sarah Lergenmüller, Frank Berthold, Markus Jensen, Peter P. Müller, Ludger Grosse-Hovest et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

 

How to Cite this Article


Kopacek, A. , Böldicke, T. , Lergenmüller, S. , Berthold, F. , Jensen, M. , Müller, P. and Grosse-Hovest, L. (2013) Construction, expression and binding specificity of bispecific CD3 × VEGFR-2 and CD3 × NCAM antibodies in the single chain and diabody format. Advances in Bioscience and Biotechnology, 4, 654-664. doi: 10.4236/abb.2013.45086.

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