American Journal of Molecular Biology

Vol.2 No.3(2012), Paper ID 20990, 7 pages

DOI:10.4236/ajmb.2012.23021

 

Knockdown of Dock7 in vivo specifically affects myelination by Schwann cells and increases myelin thickness in sciatic nerves without affecting axon thickness

 

Tomohiro Torii, Yuki Miyamoto, Motoshi Nagao, Naoko Onami, Hideki Tsumura, Masahiro Maeda, Kazuaki Nakamura, Akito Tanoue, Junji Yamauchi

 

Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
Laboratory Animal Resource Facility, National Research Institute for Child Health and Development, Tokyo, Japan
Laboratory Animal Resource Facility, National Research Institute for Child Health and Development, Tokyo, Japan
Immuno-Biological Laboratories, Co., Ltd., Gunma Japan
Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
Department of Pharmacology, National Research Institute for Child Health and Development, Tokyo, Japan
The Japan Human Health Sciences Foundation, Tokyo, Japan

 

Copyright © 2012 Tomohiro Torii, Yuki Miyamoto, Motoshi Nagao, Naoko Onami, Hideki Tsumura, Masahiro Maeda, Kazuaki Nakamura, Akito Tanoue, Junji Yamauchi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

 

How to Cite this Article


Torii, T. , Miyamoto, Y. , Nagao, M. , Onami, N. , Tsumura, H. , Maeda, M. , Nakamura, K. , Tanoue, A. and Yamauchi, J. (2012) Knockdown of Dock7 in vivo specifically affects myelination by Schwann cells and increases myelin thickness in sciatic nerves without affecting axon thickness. American Journal of Molecular Biology, 2, 210-216. doi: 10.4236/ajmb.2012.23021.

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