In biology, regeneration is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can either be complete where the new tissue is the same as the lost tissue, or incomplete where after the necrotic tissue comes fibrosis.
At its most elementary level, regeneration is mediated by the molecular processes of gene regulation and involves the cellular processes of cell proliferation, morphogenesis and cell differentiation. Regeneration in biology, however, mainly refers to the morphogenic processes that characterize the phenotypic plasticity of traits allowing multi-cellular organisms to repair and maintain the integrity of their physiological and morphological states. Above the genetic level, regeneration is fundamentally regulated by asexual cellular processes. Regeneration is different from reproduction. For example, hydra perform regeneration but reproduce by the method of budding.
Components of the Book:
- Chapter 1
A Regeneration Toolkit
- Chapter 2
Adhesive organ regeneration in Macrostomum lignano
- Chapter 3
Animal regeneration ancestral character or evolutionary novelty?
- Chapter 4
Bioengineered Lacrimal Gland Organ Regeneration in Vivo
- Chapter 5
Cellular and molecular mechanisms that regulate mammalian digit tip regeneration
- Chapter 6
Live cell-lineage tracing and machine learning reveal patterns of organ regeneration
- Chapter 7
Liver Regeneration after Hepatectomy and Partial Liver Transplantation
- Chapter 8
Macrophages and fibroblasts during inflammation and tissue repair in models of organ regeneration
- Chapter 9
Regeneration and repair of human digits and limbs fact and fiction
- Chapter 10
Regeneration mechanisms in Syllidae (Annelida)
- Chapter 11
Regeneration versus scarring in vertebrate appendages and heart
- Chapter 12
Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria
- Chapter 13
Temporal regulation of planarian eye regeneration
- Chapter 14
Uncovering the regeneration strategies of zebrafish organs a comprehensive systems biology study on heart, cerebellum, fin, and retina regeneration
- Chapter 15
Zebrafish heart regeneration 15 years of discoveries
Readership:
Students, academics, teachers and other people attending or interested in Organ Regeneration.
Mayssa H. Mokalled
Mayssa H. Mokalled
Department of Developmental Biology, Washington University School of Medicine, St. Louis,USA
Kenneth D. Poss
Kenneth D. Poss
Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA
Mekayla A. Storer
Mekayla A. Storer
Program in Neurosciences and Mental Health, Hospital for Sick Children, Toronto, Canada
Anthony L. Mescher
Anthony L. Mescher
Department of Anatomy and Cell Biology, Indiana University School of Medicine, Bloomington, Indiana University Center for Developmental and Regenerative Biology, Bloomington, USA
Carolyn E Adler
Carolyn E Adler
Stowers Institute for Medical Research, Kansas City, United States
Alejandro Sánchez Alvarado
Alejandro Sánchez Alvarado
Howard Hughes Medical Institute, Stowers Institute for Medical Research, Kansas City, USA
Anna Jaźwińska, Department of Biology, University of Fribourg, Switzerland.
and more...