Advances in In Vitro Fertilization

In vitro fertilisation (or fertilization; IVF) is a process by which an egg is fertilised by sperm outside the body: in vitro (“in glass”). The process involves monitoring and stimulating a woman’s ovulatory process, removing an ovum or ova (egg or eggs) from the woman’s ovaries and letting sperm fertilise them in a liquid in a laboratory. The fertilised egg (zygote) is cultured for 2–6 days in a growth medium and is then transferred to the same or another woman’s uterus, with the intention of establishing a successful pregnancy. It is a technique of assisted reproductive technology for treatment of infertility. In some situations, donated eggs or sperms may be used. Some countries ban or otherwise regulate the availability of IVF treatment, giving rise to fertility tourism. Restrictions on availability of IVF include costs and age to carry a healthy pregnancy to term. Due to the costs of the procedure, IVF is mostly attempted only after less expensive options have failed.


In the present book, fifteen typical literatures about In vitro fertilisation published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, female genital procedures, cryobiology, fertility medicine, obstetrics, human pregnancy, reproduction, ect. We hope this book can demonstrate advances in In vitro fertilisation as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    In Vitro Fertilization (IVF) in Mammals: Epigenetic and Developmental Alterations. Scientific and Bioethical Implications for IVF in Humans
  • Chapter 2
    Abdominal Ectopic Pregnancy after In Vitro Fertilization and Single Embryo Transfer: A Case Report and Systematic Review
  • Chapter 3
    Sperm Midpiece Apoptotic Markers: Impact on Fertilizing Potential in In Vitro Fertilization and Intracytoplasmic Sperm Injection
  • Chapter 4
    An Increase in IL-1β Concentrations in Embryo Culture-Conditionedmedia Obtained by In Vitro Fertilization on Day 3 Is Related to Successful Implantation
  • Chapter 5
    Can Cycle Day 7 FSH Concentration during Controlled Ovarian Stimulation Be Used to Guide FSH Dosing for In Vitro Fertilization?
  • Chapter 6
    Reproducibility and Clinical Significance of Pre-Ovulatory Serum Progesterone Level and Progesterone/Estradiol Ratio on the Day of Human Chorionic Gonadotropin Administration in Infertile Women Undergoing Repeated In Vitro Fertilization Cycles
  • Chapter 7
    Is In Vitro Fertilization Associated with Preeclampsia? A Propensity Score Matched Study
  • Chapter 8
    Corifollitropin Alfa Compared to Daily FSH in Controlled Ovarian Stimulation for In Vitro Fertilization: A Meta-Analysis
  • Chapter 9
    The Association of Serum Estradiol Level with Outcomes of Clomiphene Citrate/Human Menopausal Gonadotropin Ovarian Stimulation for In Vitro Fertilization and Embryo Transfer
  • Chapter 10
    Ovarian Stimulation with Human and Recombinant Gonadotropin – Comparison of In Vitro Fertilization Efficiency with Use of Time-Lapse Monitoring
  • Chapter 11
    Cycle Scheduling for In Vitro Fertilization with Oral Contraceptive Pills versus Oral Estradiol Valerate: A Randomized, Controlled Trial
  • Chapter 12
    Oocyte Zona Pellucida Dysmorphology Is Associated with Diminished In-Vitro Fertilization Success
  • Chapter 13
    Plasma Concentrations of D-Dimer and Outcome of In Vitro Fertilization
  • Chapter 14
    Efficiency of Metaphase II Oocytes Following Minimal/Mild Ovarian Stimulation In Vitro Fertilization
  • Chapter 15
    Satisfaction with In Vitro Fertilization Treatment: Patients’ Experiences and Professionals’ Perceptions
Readership: Students, academics, teachers and other people attending or interested in In-Vitro Fertilization (IVF).
Reshef Tal, Division of Reproductive Endocrinology & Infertility, Department of Obstetrics, Gynecology, & Reproductive Sciences, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA.

Joanna Talarczyk-Desole, Division of Infertility and Reproductive Endocrinology, Poznan University of Medical Sciences, Polna 33, 60-535 Poznan, Poland.

Yaakov Bentov, Toronto Centre for Advanced Reproductive Technology, Toronto, ON,Canada.

Yu-Ju Lin, Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Takeo Fujiwara, Department of Social Medicine, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan.

Gian Mario Tiboni, Dipartimento di Medicina e Scienze dell’Invecchiamento, University “G. d’Annunzio” of Chieti-Pescara, Chieti, Italy.

and more...
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