Fatty liver, or
hepatic steatosis or simple steatosis, is a reversible condition wherein large
vacuoles of triglyceride fat accumulate in liver cells via the process of
steatosis (i.e., abnormal retention of lipids within a cell). Despite having
multiple causes, fatty liver can be considered a single disease that occurs
worldwide in those with excessive alcohol intake and the obese (with or without
effects of insulin resistance). The condition is also associated with other
diseases that influence fat metabolism. When this process of fat metabolism is
disrupted, the fat can accumulate in the liver in excessive amounts, thus
resulting in a fatty liver. It is difficult to distinguish alcoholic FLD, which
is part of alcoholic liver disease, from nonalcoholic FLD (NAFLD), and both
show microvesicular and macrovesicular fatty changes at different stages.
In the present book, twelve typical literatures about fatty liver disease published on international authoritative
journals were selected to introduce the worldwide newest progress, which
contains reviews or original researches on grades of fatty liver, nonalcoholic fatty liver disease, liver histology, liver enzymes and metabolic syndrome, etc. We hope this book can
demonstrate advances in fatty liver disease as well
as give references to the researchers, students and other related people.