Biography
Maduike Chiehiura Onwubiko Ezeibe


Educational institutions attended and qualifications obtained:

College of Veterinary surgeons Nigeria, FCVSN, 2015.

College of Veterinary Suegeons Nigeria,   MCVSN, 2004.

University of Nigeria, Nsukka, Ph. D. 2002.

University of Nigeria, Nsukka, M. Sc. 1994.

University of Nigeria, Nsukka DVM, 1986 with distinction in Veterinary Public health and Jurisprudence


Area of specialization:

Veteriany clinical virology.


Academic/Professional Career:


Institutions:

Postions held with Dates:

Anambra state Ministry of Agriculture

Vet. Officer (National Youths Service Corps)

1986-1987

Sal Vet. Services Nig. Ltd. Aba

Private practice

1987-1992.

University of Nigeria, Nsukka

Graduate Assistant

1992-1994.

University of Nigeria, Nsukka

Lecturer II

1994-2000.

University of Nigeria, Nsukka

Senior Lecturer

2000-2005

University of Nigeria, Nsukka

Reader

2005-2011

University of Nigeria, Nsukka

Professor

2011 - 2013

Michael Okpara Univ. of Agric., Umudike

Professor

2013 - Date


List of the Publications and Patents.


A. Articles.

1. Wosu, L.O. and Ezeibe, M.C.O. (1991). Haemagglutination-Inhibition technique for definitive diagnosis of PPR virus specific antibody.Biomedical Letters 48:173-177.


2. Wosu, L.O. and Ezeibe, M.C.O. (1992). Haemagglutination-Inhibition technique for definitive diagnosis of Rinderpest virus specific antibody.Better:Landwirtsch.Vet. Med. 30:299-304.


3. Ezeibe, M.C.O. (1997). Observations on natural outbreaks of Aspergilloisis in chickens in Nsukka, Enugu StateNigeria. Nig. Vet. J. 18(2):245-248.


4. Ezeibe, M.C.O. and Wosu, L.O. (1997). Clinical signs of PRR in natural field outbreaks. Nig. Vet. J. 18(2): 247-252.


5. Ezeibe, M.C.O. and Wosu, L.O. (1997). Reproductive ability of female goats, following recovery from PPR. Small Ruminant Research. 187-189.


6. Ezeibe, M.C.O. (1998). Management of vaccine-induced infectious Bursal disease in Chicks with antibiotics and antidiarrhoeics. Nig. J. Anim. Prod. 24(2): 86-89.


7. Ezeibe, M.C.O. (1998). Management of different stages of field outbreaks of Gumboro disease. Proc. WASAP. Conf. Abeokuta. Pp 82-83.


8. Ezeibe, M.C.O. (1998). Giardiasis in a flock of rabbits in Nigeria. Proc. WASAP Conf. Abeokuta. Pp. 81.


9. Ezeibe, M.C.O. (1998). A case of Aspergillosis in mature Turkeys. Proc. WASAP Conf. Abeokuta. Pp. 86.


10. Ezeibe, M.C.O. (1999). PPR disease of sheep and goats-need for public education. Proc. 5th Ann. Conf. Agric. Ext. Soc. Nig. Pp.30-33.


11. Ezeibe, M.C.O. and Ozoemena, U.B. (2000). Evaluation of virus titre and seroconversion ability of foreign Newcastle vaccines [IaSota] imported into  Nigeria. Proc. NSAP. Pp 296.298.


12. Ezeibe, M.C.O. and Agwu, U.K. (2000). Seroconversion activities of oil emulsion and water based Newcastle disease vaccines. Proc. 27th Conf. NSAP. Pp. 70-71.


13. Ezeibe, M.C.O. (2000). Reoccurrence of PPR in Kids. Nig. Vet. J. 21:27-29.


14. Ezeibe, M.C.O. (2000). Canine distemper: A review. Studies and Research in Vet. Medicine 8:99-101.


15. Ezeibe, M.C.O. and Wosu, L.O. (2000). Ondersteport Canine distemper vaccine and measles vaccine protect Nigerian dogs against local isolate of Canine distemper virus. Nig. Vet. J. 23(2):51-55.


16. Ezeibe, M.C.O. (2001). Haemaggluitination technique for detection of Newcastle disease virus in live Chickens. Nig. Vet. J. 22(1):37- 41.


17. Ezeibe, M.C.O. (2003). Clinical Manifestations of Canine distemper in Nigerian Dogs infected with local isolate of Canine distemper virus. Nig. Vet. J. 24(1):44-47.


18. Ezeibe, M.C.O. (2003). Indirect haemagglutination-Inhibition (HI) test for Canine distemper. Studies and Researches in Vet. Medicine. Supplement (1):11-15.


19. Ezeibe, M.C.O., Wosu, L.O. and Erumaka, I.G. (2004). Standardization of haemagglutination test for PPR. Small Ruminant Research 51:269-272.


20. Ezeibe, M.C.O. and Akpa, E.C. (2004). Presence of None specific haemagglutinins in sera of some Animal species found in Nigeria. International J. Agric. Biol. Sc.3 : 29 – 31.


21. Ezeibe, M.C.O. and Anyalewechi, O.C. (2004). Canine distemper associated with generalized Oedema in Nigerian dogs. Trop. Vet. 22(2):53-56.


22. Ezeibe, M.C.O. and Ngene, A.A. (2004). Agglutination of chicken red blood cells by tissue homogenate of goats naturally infected with PPR virus.Proc. 29th Ann. Conf. NSAP. Pp. 56-57.


23. Ezeibe, M.C.O. (2004).Detection of Peste des petitis Ruminants virus in faeces of sick and recovering goats ,29th Ann. Conf. NSAP. Pp. 89-91.


24. Ezeibe, M.C.O. (2004). Admacine® .Research and National Development Proc. Distinguished LecturerP.G. School U.N.N. Pp. 104-105.


25. Ezeibe, M.C.O. (2004). Francoccine®. Research and National Development Proc. Distinguished Lecturer P.G. School U.N.N. Pp. 105-106.


26. Ezeibe, M.C.O. (2004). Chi-travite®. Research and National Development Proc. Distinguished Lecturer P. G. School U. N. N. P.106.


27. Ezeibe, M.C.O. (2005). Canine distemper disease in Nigerian local dogs. Veterinary Records. 156:840-842.


28. Ezeibe, M.C.O. (2005). Symptomatic Management of PPR in West African dwarf goats J. Sust. Agric. Environ. 7(1):11-14.


29. Ezeibe, M.C.O. (2005). Relative Resistance of goats to PPR following a sheep to goats transmission of infection. J. Sust. Agric. Environ. 7(1):15-18.


30. Ezeibe, M.C.O. and Ndip, E.T. (2005). Red Blood cells Elution Time of Strains of Newcastle disease virus. J. Vet. Sc. 6(4):287-288.


31. Ezeibe, M.C.O.; Gbaruko, J.K. and Asuzo, C. (2005). Prevalence of Canine distemper in Nsukka Local Government Area of Enugu State, Nigeria. Vom. J. Vet. Sc.2:52 – 56.


32. Shoyinka, S.V.O.; Emehelu, C.O. and Ezeibe, M.C.O. (2005). MalignantMastocytoma in a Nigerian local Dog. Nig. Vet. J. 26(2): 45-50.


33. Okoli,I. C.,Opara,M.N.,Anosike, J. C.,Uko, J. U., Agaie,B.M., Garba,H. S.,Jibike,G. I.,Nwosu,C.I.,Nwanta,J. A.,Fayomi,A.,Abiade – Paul, C. U.,Chah,K. F.,Ezeibe, M.C.O. Ajuwape,A.J.P.,Olafa,A.K.,Wehke,S.N.and Oboegbulam,S. I.. (2006). The epizootiology of the highly pathogenic avian influenza prior to the anticipated pandemic of the early twenty first century. Anim. Prod. Res. Adv. 2(1):50-56.


34. Obidike,R.I.,Ezeibe, M.C.O.,Omeje,J.T.N and Ugwuomarima,K.G. (2006). Incidence of Peste des petits ruminants haemagglutinins in farm and market goats in Nsukka, Enugu State, Nigeria. Bull.Anim. Hlth. Prod. Afr. 54:148- 150.


35. Ezeibe, M.C.O., Eze, I.C., Nwokike, E.C. and Eze, J.I. (2006). Detection and Characterization of Newcastle disease virus from faeces of healthy free-roaming chickens in Nsukka, Nigeria. Trop. Vet. 24:76-80.


36. Ezeibe, M.C.O., Okoroafor, O.N., Eze, J.I. and Eze, I.C. (2007). Seroprevalence of egg drop syndrome-76 virus as cause of poor egg productivity of poultry in Nsukka , South East Nigeria. Trop. Anim. Health and Prod. 39:493-505.


37. Ezeibe, M.C.O., Eze, I.C., Okoroafor, O.N., Ugonabo, J.A.C., Ngene, A.A. and Eze, J.I. (2008). Persistent detection of Peste de petits ruminants  antigen in faeces of recovered Goats. Trop. Anim Health and Prod. DOI: 10.1007/s11250-008-

      91283.


38. Ezeibe, M.C.O., Eze,J. I. and Eze, I.C (2008). Agglutination of red blood cells by Canine distemper virus. Nig. Vet. J. 29(1):57- 62.


39. Nwaogu, I.C., Ezeibe, M.C.O. and Ifeduba, O.F. (2008). Effects of Alcohol consumption on homoral immunity in mice. J. App. Anim. Res. 34:181-18


40. Ezeibe, M. C. O.and Udegbunam, R. I.(2008). Haematology of dogs infected with Canine distemper virus. Sokoto J. Vet. Sc. 7(2) :32 – 34.


41. Ezeibe, M.C.O., Mbuko, I.J., Okoroafor, O.N., Okonkwo, A.C., Animoke, P.C., Orajaka, L.J.E and Ngene, A.A. (2009). In vitro and in vivo effects of Aluminum-magnesium silicate on Infectious bursal disease virus in chiken.Anim. Sc. Rep. 3(4):132-137.


42. Ezeibe, M.C.O., Ijabo, O., Okoroafor, O.N., Orajaka, L.J.E., Ukomadu, N.M. Chukwu, O.S. and Ngene, A.A. (2009). Antiviral effects of Aluminum-magnesium silicate on Peste des Petits Ruminants Virus.Anim. Sc. Rep. 3(4):141-147.


43. Ezeibe, M.C.O., Eze, J.I., Ijabo, O., Ngene, A.A., Okoroafor, O.N., Ukomadu,N.M., Sanda, E.M., Eze, I.C. and Ugonabo, J.A.C (2010).  Standardization of the PPR haemagglutinin antigen for haemagglutination-inhibition test. J. Appl. Anim. Res.38:113 – 115.


44. Ezeibe, M.C.O., Eze, J.I., Ijabo, O., Ngene, A.A., Okoroafor, O.N., Ukomadu, N.M., Sanda, E.M., Eze, I.C. and Ugonabo, J.A.C(2010).  Immune response of rats to PPR vaccination.J. Appl. Anim. Res.37(2) : 239 – 240.


45. Ezeibe, M.C.O., Okoroafor, O.N., Nwaoga, R.O.,  Ngene, A.A and Eze, J. I.(2010).  Effect of B-vitamins on immune response of dogs to canine distemper vaccination. Anim. Sc. Rep.4 (3) :83 – 86.


46. Ezeibe, M.C.O., Okoroafor, O.N., Ijabo, O., Ukomadu, N.M.,  Ngene, A.A and Eze, J. I.(2010).  Haemagglutination-inhibition and Haemagglutination titres of Egg drop syndrome 76 virus treated with Aluminum-magnesium silicate. Anim. Sc. Rep.4(3) :87 – 90.


47. Ezeibe, M. C. O., Nwaogu, I. C., Nwaigwe, A. N., Okoroafor, O. N. Eze, J. I. and Ngene, A. A. (2010).  Aluminum – magnesium silicate inhibits canine parvovirus and cures infected dogs .Health.2 (10) : 1215 – 1217.


48. Ezeibe, M. C. O.,Okafor,U. C., Okoroafor, O. N.,Eze,J.I., Ngene, A.A.,Animoke,P. C. and Mbuko, I. J.(2011). Effect of Aluminum-magnesium silicate on anticcocidial activity of Sulphadimidine.Tropical Veterinarian. 29 :41  - 44.


49. Ezeibe, M. C. O., Ijabo, O., Uzopuo, C., Okoroafor, O. N., Eze, J. I. Mbuko, I. J., Sanda, M. E., Animoke, P. C. and Ngene, A. A.(2011 ). Effects of Aluminium – Magnesium Silicate on Newcastle disease virus and on recovery of infected chicks.Int. J. Biol. Chem. 5(2): 825 – 829 .


50. Ezeibe, M. C. O.,Udegbulam, R. I., Shoyinka, S. V. O. and  Anyalebechi, O. C. (2011). Urinalysis and  Gross pathology of  Nigerian dogs infected with local isolates of the Canine distemper virus. J. Vet. Appl. Sci. 1 (1) : 16 – 20.


51. Ezeibe, M. C. O.,Udegbulam, R. I., Etim, N. Eze, J. I. Okoroafor, O. N, Sanda, M. E, Udegbulam, S. O , Ugonabo, J.A. C and  Ngene,A. A (2011). Determination of blood coagulation time for clinical differentiation of Canine distemper from Canine trypanosomosis J. Vet. Appl. Sci. 1 (1) : 27 – 30.


52. Ezeibe, M.C.O.,Egbuji, A.N., Eze, J.I., Ijabo, O., Ngene, A. A.,Okoroafor, O. N., Eze, I. C., Ugonabo, J. A. C,. Sanda, M. E. and Mbuko I. J.(2012).Antiviral Effects of a synthetic Aluminum-magnesium silicate on Avian Influenza Virus . Health 4(7) : 429 – 432.


53. Ezeibe, M. C. O. ,Elendu – Eleke, N. P., Okoroafor, O. N. and Ngene ,A. A (2012). Adjuvant effect of a synthetic Aluminum – magnesium silicate on Chloroquine phosphate against Plasmodium berghei. Nature precedings:hdt 10101/npre 20126749.1.posted 2 Jan.2012.


54. Ezeibe, M. C. O.,Anosa,G.N.,Okorie,O.K., Elendu – Eleke,N. P.,Okoroafor, O. N, Ngene,A. A.and Chikelu, O. N.(2012).Aluminum – magnesium silicate enhances antibacterial activity of Ampicilline trihydrate,against S.gallinarum. Nature precedings:http:hdt.handle.net/10101/npre.2012.6814.1.posted 23 Jan.2012.


55. Sanda,M. E., Ezeibe,M. C. O. and Anene,B. M.(2012).Survey of Newcastle Disease immune levels of sellected poultry farms in Dekina Local Government Area of Kogi State, Nigeria.Nig. J.Fd. Drg. Hlth.5(1): 79 – 82.


56. Ezeibe, M. C . O. Okoye,J.O.A.,Ogunniran,T.M,Okoroafor,O.N,Ezeala,I.E and Ngene,A.A.(2012). Modification  of the Passive Heamagglutination  Test for  Detection  of Infectious Bursal Disease Virus.Health 4(9): 653 – 655.


57. Ezeibe, M, C. O ,Dire, C.D, Anosa, G. N ,Chikelu, O. N, Okoroafor, O. N, Okorie, O. K., Ngene, A. A.,  Idika, I. K,Ogunniran,T. M.  and Ezeala, I. E (2012). Efficacy of Piparazine Citrate, stabilized with Aluminum – magnesium silicate, against Helignosomoides bakeri. Health4(10) : 890-892.


58. Ezeibe,M. C. O., Chima,U. M., Ngene, A. A., Okoroafor, O. N.,Kalu,I.I and Esen, M. E.(2012).Effective treatment of  resistant Escherichia coliinfection, with Sulphadimidine stabilized in a synthetic Aluminum-magnesium silicate. Health4(12):1295-1298.


59. Ezeibe, M. C. O.(2012). Highly pathogenic Avian Influenza Virus disease (Bird Flu)- Recommended control measure. JVAS  2(1): 8 – 14.


60. Ezeibe, M. C. O., Animoke, P. C., Mbuko, I. J., Sanda, M. E., Nnoje, C., Okafor, U. C., Ngene, A. A. and Oguniran, T. O.(2012). Seroprevalence of Infectious bursal disease in day old chicks and immune response of chicks to vaccination against the disease.JVAS 2 (1): 36 -40.


61. Ezeibe, M. C. O. ,Elendu-Eleke, N.P., Anyaora, U., Okoroafor, O.N.,Ngene,A.A.,Eze, J. I. and Ugonabo, J.A.C.(2012).Incidence of zoonotic helminth parasites in non-human primates at the zoological garden of University of Nigeria, Nsukka, South East Nigeria. JVAS 2(1): 45 – 48.


62. Ezeibe,M. C. O,  Okoye, J. O. A, Ogunniran, T. M., Animoke, P.  C., Mbuko, I. J. , NwankwoI. A and  Ngene,Augustine A(2013).Mortality rates from a Nigerian isolate of the Infectious Bursa Disease Virus and Passive haemagglutination  antibody titer that protects chicks against  challenge with the virus. Health 5(9):1355-1359.


63. Ezeibe, M. C. O., Ngene ,A. A. Anene, I.  Amechi, B. Olowoniyi , P.Eze, J. I. and Animoke, P. C.(2013). Direct passive hemagglutination test for rapid quantification of plasma loads of the Human immunodeficiency Virus.Health 5(9):1351-1354.


64. Ezeibe, M. C. O., Ekeanyanwu, E.,  Ngene, A. A. and  Mbuko, I. J.(2013).

Aluminum-magnesium silicate enhances release of virions  of cultured Fowlpox Virus and inhibits the virus. Health.5(9):1394-1396.


65. Ezeibe, M. C. O., Ezeobele,O. K, Esen, M.E., Ngene, A. A., Mbuko, I. J. Chukwudi, I. C., Omoja, V. U. and Ezeh, I. O.(2013) Synergy in  antibacterial  activities of Ampicillin  trihydrate, stabilized with a synthetic Aluminum-magnesium silicate and immune-stimulants, on  resistant Escherichia coli infection.Health 5(10): 1548 -1552.


66. Ezeibe,M. C. O.,Okoye, J. O. A.,Ogunniran, T. M., Animoke,P. C., Ijeoma. J. Mbuko,I. J.,Nwankwo, I. A and Ngene,A. A.(2014).Effects of live Infectious bursa disease .vaccines, on immune response of vaccinated chicks. BJMMR. 4(7) : 1506 - 1513.


67. Ezeibe, M. C. O., Ngene, A.A., Kalu,I.K., Ezeh, I. O., Mbuko, I. J.,Ekwuruke,J.O., Anene,I.,Amechi,B.,Olowoniyi,P.and Ifekwe, I. F.(2014).Assessment of Antiretroviral effects of a synthetic Aluminum-magnesium silicate. BJMMR 4(8) :1672 - 1679.


68. Ezeibe, M. C. O., Okoye, J. O. A, Ezeala, I. E., Mbuko, I. J. and Ngene, A. A.(2014).Comparison of Agglutination of Mammalian erythrocytes plus heat stability tests and agglutination of mammalian erythrocytes plus erythrocyte elution time to a standard method, for characterizing field isolates of Newcastle disease virus.BMRJ, 4(7): 730-736.


69. Ezeibe, M. C. O., Okoye, J. O. A.,  Ezeala, I. E., Mbuko, I. J. and Ngene, A. A.(2014). Strains  of Newcastle disease virus circulating among sick poultry flocks  in Nsukka, Nigeria.BMRJ5(4): 384-388.


70. Ezeibe, M.C.O. and Ogbonna, I.J. (2015).  Acquired Immune Deficiency Syndrome in Man and Animals— A Review. World Journal of AIDS,5, 50-57.


71. Ezeibe, M.C.O. and Ogbonna, I.J. (2015). In vivo Antiretroviral Effects of the Medicinal Synthetic Aluminum-Magnesium Silicate. World Journal of AIDS, 5: 59-65.


72. Ezeibe, M.C.O. and Ogbonna, I.J. (2015).Enhancing efficacy of antimicrobials with theMedicinal Synthetic Aluminum-Magnesium Silicate, for prevention and treatment of resistant Infections.BJMMR. 9(6): 1-8.


73. Sanda, M. , Ezeibe, M. C. O. and Anene, B. M(2015). Effects of Vitamins A,  C and E and Sellenium on immune response of broilers to Newcastle vaccine. J. Agric.and Vet, sc 8(7): 13 – 15.


74. Sanda, M. , Ezeibe, M. C. O. and Anene, B. M(2015). Effect of Routes of Administration on Immune Response of Broiler Chicks to Newcastle Disease Vaccine (LaSota) J. Appl. Life Sc. Int 3(3): 138-142.


75. Ezeibe, M. C. O. and Ogbonna, I. J.(2016). Medicinal synthetic Aluminum-magnesium silicate{Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3} – Ahighly activeanti-retroviral medicine. World Journal of AIDS(In print).


76. Ezeibe, M.C.O., Aleeyu, D., Ogbonna, I.J. and Kalu, E. (2016) Clinical Trial of Medicinal Synthetic Aluminum-Magnesium Silicate (Antivirt®) on Viral Loads and CD4-Lymphocytes Counts of HIV/AIDS Patients. World Journal of AIDS, 6, 37-41. http://dx.doi.org/10.4236/wja.2016.62005.


77. Ezeibe, M.C.O,Aleeyu, D., Aneke, N.K., Obarezi, T.N., Ogbonna, I.J. and Kalu, E. (2016). Assessment of Antiretroviral Efficacy of the Medicinal Synthetic Aluminum-Magnesium Silicate {Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3}.

World Journal of AIDS, 6, 74-80. http://dx.doi.org/10.4236/wja.2016.62011.


78. Ezeibe, M. C. O.,  Aleeyu, D.  Aneke, N. K., Obarezi, T. N.,  Ogbonna1, I. J.,  Kalu,  E. and  Njoku, N. U.(2016).HIV/AIDS Recovery Rates in Male and FemalePatients, Treated with Medicinal synthetic Aluminum-magnesium silicate. BJMMR.18: 1-7.


79. Ezeibe, M. C. O.,  Aleeyu, D.  Aneke, N. K., Obarezi, T. N.,  Ogbonna1, I. J.,  Kalu,  E. and  Njoku, N. U.(2017). Responses of patients at different stages of HIV-infection, to treatment with Medicinal synthetic Aluminum-magnesium silicate`s{Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3}.BJMMR(Accepted for publication).


B. Books.

1. Maduike Ezeibe (2009). Culture and traditions of my people. Great Ap Express publishers Limited, Nsukka, Nigeria.


2. Maduike Ezeibe (2017).Avian Newcastle disease: Ethical methods of characterizing the virus. Lambert academic publishing. Germany.


3. Maduike Ezeibe (. . .).The medicinal synthetic Aluminum-magnesium silicate. . ..


C. Patents

1. Ezeibe M.C.O. (2006).Admacine®. Federal Republic of Nigeria Patents and Designs Act.  Cap 344 LFN 1990, NO. RP 16446.


2. Ezeibe M.C.O. (2006). Franccocine®. Federal Republic of Nigeria Patents and Designs Act.  Cap 344 LFN 1990, NO. RP 16447.


3. Ezeibe, M.C.O. (2014). Medicinal synthetic Aluminum-magnesium silicate (Nanoparticles) – Antiviral agent and adjuvant to chemotherapeutics. Federal Republic of Nigeria Patents and Designs Ref No.: NG/P/2012/639.


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