Phytochemical Study of Glycosmis Mauritiana

Javed Intekhab, Mohammad Aslam, Hira Khalid

.

DOI: 10.4236/ajps.2011.25078                

Abstract

Three quinolinone alkaloids, two acridone alkaloids and a flavones glycoside were isolated from the aerial parts of Glycosmis mauritiana. These compounds were characterized as 7, 8-Dimethoxy-2,2,6-trimethyl-pyrano quinolin-5-one, 4-Methoxy 1-methyl quinolin-2-one, 6-Hydroxy N-methyl 2,3-furo-quinolin-4-one, 1-Hydroxy-10-methyl acridone, 1- Hydroxy-2, 3-dimethoxy-10-methylacridin-9-one and Luteolin-4'-O-[α-L-rhamnopyranosyl-(1→2)-{α-L-rhamnopyra- nosyl-(1→6)}-β-D-glycopyranoside]. The isolated compounds were characterized by UV, IR and N. M. R (¹H, ¹³C) studies.

Keywords

Glycosmis Mauritiana, Rutaceae, Flavanone Glycoside

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	P. G. Watermann and M. F. Grundon, “Chemistry and Chemical Taxonomy of the Rutales,” Academic Press, London, 1983.
[2]	O. Hofer and H. Greger, “Sulfur-Containing Amides from Glycosmis Species: Rutaceae,” W. Herz, H. Falk, G. W. Kirby and R. E. Moore, Eds., Springer, New York, Vol. 80, 2000, p. 187.
[3]	B. C. Stone, “A Conspectus of the Genus Glycosmis Correa: Studies in Malaysian Rutaceae, III,” Proceedings of the Academy of Natural Sciences of Philadelphia, Vol. 137, 1985, pp. 1-27.
[4]	N. M. Cuong, T. V. Sung and W. C. Taylor, “Glypetelotine, a Sulphur-Containing Indole Alkaloid from Glycosmis petelotii,” Phytochemistry, Vol. 52, No. 8., 1999, pp. 1711-1714. doi:10.1016/S0031-9422(99)00402-1
[5]	M. Rahmani, C. Y. Ling, M. A. Sukari, H. B. M. Ismail, S. Meon and N. Aimi, “7-Methoxyglycomaurin: A New Carbazole Alkaloid from Glycosmis rupestris,” Planta Medica, Vol. 64, No. 8, 1998, p. 780. doi:10.1055/s-2006-957588
[6]	T.-S. Wu, Feng-Chu, C., & Pei-Lin, W., “Flavonoids, Amidosulfoxides and an Alkaloid from the Leaves of Glycosmis citrifolia,” Phytochemistry, Vol. 39, No. 6, 1995, p. 1453-1457. doi:10.1016/0031-9422(95)00171-3
[7]	C. W. J. Chang, W. Herz, H. Greger, H. Falk, O. Hofer, G. W. Kirby, “Fortschritte Der Chemie Organischer Naturstoffe/Progress in the Chemistry,” Springer, Berlin, Vol. 80, 2000, p. 188.
[8]	R. E. Catherinefl, “Flavonoids in Health and Disease,” 2nd Edition, Marcel Dekker, Inc., New York, 2003.
[9]	G. Erich, “The Science of Flavonoids,” Springer Science, New York, 2006.
[10]	C. G. Fraga, “Plant Phenolics and Human Health Published,” John Wiley and Sons, Hoboken, 2010.
[11]	W. Bylka and I. Matlawska, “Natural Flavonoids as Antimicrobial Agents,” JANA, Vol. 7, No. 2, 2004, pp. 24-31
[12]	L. G. Korkina and I. B. Afanas’ev, “Antioxidant and Chelating Properties of Flavonoids,” Advances in Pharmacology, Vol. 38, 1997, pp. 151-163. doi:10.1016/S1054-3589(08)60983-7
[13]	C. A. Rice-Evans, N. J. Miller and G. Paganga, “Structure-Antioxidant Activity Relationships of Flavonoids and Phenolic Acids,” Free Radical Biology and Medicine, Vol. 20, No. 7, 1996, pp. 933-956. doi:10.1016/0891-5849(95)02227-9
[14]	S. Charles, N. I. Buer and A. Michael, “Djordjevic Flavonoids: New Roles for Old Molecules,” Journal of Integrative Plant Biology, Vol. 52, No. 1, 2010, pp. 98-111. doi:10.1111/j.1744-7909.2010.00905.x
[15]	A. R. Tapas, D. M. Sakarkar and R. B. Kakde, “Flavonoids as Nutraceuticals: A Review,” Tropical Journal of Pharmaceutical Research, Vol. 7, No. 3, 2008, pp. 1089-1099
[16]	O. M. Andersen and K. R. Markham, “Flavonoids: Chemistry, Biochemistry, & Applications,” CRC Press, Taylor & Francis, London, 2006.
[17]	K. R. Markham, “Techniques of Flavonoid Identification,” Academic Press, London, 1982.
[18]	T. J. Mabry, K. R. Markham and M. B. Thomas, “The Systematic Identification of Flavonoids,” Springer, New York, 1970, pp. 24-26, 147, 332-333.
[19]	K. R. Markham and T. J. Mabry, “Ultraviolet-Visible and Proton Magnetic Resonance Spectroscopy of Flavonoids,” In: J. B. Harborne, T. J. Mabry and H. Mabry, Eds., The Flavonoids, Chapman and Hall, London, 1975, pp. 45-77.
[20]	J. B. Harborne and H. Baxter, “The Handbook of Natural Flavonoids,” John Wiley and Sons, Chichester, Vol. 1-2. 1999.
[21]	P. K. Agrawal, “Carbon-13 NMR of Flavonoids,” Elsevier, Amsterdam, 1999.