Functionalization of Cobalt Ferrite Nanoparticles with Alginate Coating for Biocompatible Applications

Prasad M. Tamhankar, Aparna M. Kulkarni, Shrikant C. Watawe

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DOI: 10.4236/msa.2011.29179                

Abstract

The soft magnetic materials have potential applications in the field of bioengineering as carriers for targeted drug delivery. The magnetic properties, particle size after coating, Curie temperature and its biocompatibility are important parameters for the synthesis of materials. In the present communication cobalt ferrite nanoparticles have been synthesized using co-precipitation method and coated with sodium alginate. The X-ray diffraction and infrared spectroscopic measurements have been used to confirm the ferrite structure formation and coating of the samples with alginate. The SEM micrographs have been used to confirm the particle size which is found to be 45 nm before coating and 78 nm after coating. The saturation magnetization obtained using the hysteresis data for the uncoated cobalt ferrite sample is 19.8 emu/gm while for the coated sample it reduces to 10.2 emu/gm. The AC susceptibility measurements indicate SP structure for the uncoated samples with Curie temperature less than 100℃. The thermo gravimetric measurements have been used to estimate the amount of alginate coating on the sample and it has been correlated with retention of magnetic properties after coating. The value of saturation magnetization reduces after coating due to mass reduction of magnetic material in the sample in accordance with the TGA measurements.

Keywords

Nanomagnetic Materials, Biocompatible Coating, Co-precipitation Method

Conflicts of Interest

The authors declare no conflicts of interest.

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