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Analysis on the clinical and endoscopic parameters in 1247 patients with reflux esophagitis

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DOI: 10.4236/ojgas.2014.41004    3,450 Downloads   4,546 Views   Citations

ABSTRACT

Aim: To summarize and analyze the clinical and endoscopic parameters in patients with reflux esophagitis(RE). Methods1247 patients with RE were diagnosed in our hospital endoscopy center from September 2010 to August 2012. The general information of the patients and the relationship between endoscopic classification and concomitant diseases were analyzed. Results: According to the endoscopic findings, 1247 subjects (4.70%) were found to have RE932 (74.74%) males and 315 (25.26%) females, and the male to female ratio was 2.96:1. The peak age of prevalence was 50 to 59 (27.35%) which is followed by 40 to 49 (23.10%). In this study, most of the patients had a mild degree of esophagitis representing LA-A in 60.63% and LA-B in 34.24%. The antrum hyperemia was found in 291 patients with esophagitis (23.34%), followed by antrum erosion (20.13%) and hatal hernia (15.88%). There is no statistically significant relevance between Helicobacter pylori infection and RE (P > 0.05), but Barrett’s esophagus, duodenal ulcer, gastroesophageal tumors, a history of gastroesophageal surgery and antrum hyperemia were found to be associated with RE (P < 0.05). Conclusion: The prevalence rate of endoscopic RE in our study was 4.70%, and most patients had a mild grade esophagitis. Male, advanced age, Barrett’s esophagus, duodenal ulcer, gastroesophageal tumors and a history of gastroesophageal surgery are the risk factors of esophagitis. Antrum hyperemia may reduce the severity of RE.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Zhang, X. , Wang, H. , Wang, W. , Chen, X. and Liu, H. (2014) Analysis on the clinical and endoscopic parameters in 1247 patients with reflux esophagitis. Open Journal of Gastroenterology, 4, 19-23. doi: 10.4236/ojgas.2014.41004.

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