Share This Article:

Coccidioidomycosis of the Testis and Epididymis

Abstract Full-Text HTML XML Download Download as PDF (Size:150KB) PP. 87-89
DOI: 10.4236/oju.2013.32017    3,555 Downloads   5,204 Views   Citations


This report describes an unusual presentation of a man with a testicular mass who presented in diabetic ketoacidosis to the emergency department. Initial diagnosis was a suspected testicular malignancy based on history, physical exam, and available laboratory and radiological imaging. Due to the possibility of a testicular malignancy, the patient was taken for immediate orchiectomy. Histology revealed coccidioido-mycosis of the left testicle and epididymis. Treatment with the appropriate antifungals was initiated. Despite aggressive multi-disciplinary therapy the patient continued to deteriorate and eventually expired as a result of the massive systemic infection. Literature review revealed the presentation of disseminated genitourinary coccidioidomycosis is rare and seldom reported.

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

D. Klett and Y. Hong, "Coccidioidomycosis of the Testis and Epididymis," Open Journal of Urology, Vol. 3 No. 2, 2013, pp. 87-89. doi: 10.4236/oju.2013.32017.


[1] N. M. Ampel, “Chapter 200: Coccidioidomycosis,” In: D. L. Longo, A. S. Fauci, D. L. Kasper, S. L. Hauser, J. L. Jameson and J. Loscalzo, Eds., Harrison’s Principles of Internal Medicine, 18th Edition, McGraw-Hill, New York, 2012.
[2] D. A. Stevens, “Coccidioidomycosis,” New England Journal of Medicine, Vol. 332, No. 16, 1995, pp. 1077-1082. doi:10.1056/NEJM199504203321607
[3] G. J. Wise, G. S. Talluri and V. K. Marella, “Fungal Infections of the Genitourinary System: Manifestations, Diagnosis, and Treatment,” Urologic Clinics of North America, Vol. 26, No. 4, 1999, pp. 701-718. doi:10.1016/S0094-0143(05)70212-3
[4] H. M. Weyrauch, F. W. Norman and J. B. Bassett, “Coccidioidomycosis of the Genital Tract,” California Medicine, Vol. 72, No. 6, 1950, pp. 465-468.
[5] J. G. Rohn, J. C. Davila and T. E. Gibson, “Urogenital Aspects of Coccidioidomycosis: Review of the Literature and Report of Two Cases,” Journal of Urology, Vol. 65, No. 4, 1951, pp. 660-667.
[6] G. Amromin and C. M. Blumenfeld, “Coccidioidomycosis of the Epididymis,” California Medicine, Vol. 78, No. 2, 1953, pp. 136-138.
[7] J. M. Pace, “Coccidioidomycosis of the Epididymis,” Southern Medical Journal, Vol. 48, No. 3, 1955, pp. 259-260. doi:10.1097/00007611-195503000-00007
[8] H. Bodner, A. H. Howard and J. H. Kaplan, “Coccidioidomycosis of the Spermatic Cord; Roentgen Therapy— Report of a Case,” The Journal of the International College of Surgeons, Vol. 32, 1959, pp. 530-532.
[9] B. G. Stewart, “Epididymitis and Prostatitis due to Coccidioidomycosis: A Case Report with 5-Year Follow-Up,” Journal of Urology, Vol. 91, 1964, pp. 280-281.
[10] S. Weitzner, “Coccidioidomycosis of Prostate and Epididymis—Case Report and Review of Literature,” Southwest Medical, Vol. 49, No. 4, 1968, pp. 67-69.
[11] S. F. Cheng, “Bilateral Coccidioidal Epididymitis,” Urology, Vol. 3, No. 3, 1974, pp. 362-363. doi:10.1016/S0090-4295(74)80124-X
[12] J. E. Gottesman, “Coccidioidomycosis of Prostate and Epididymis with Urethrocutaneous Fistula,” Journal of Urology, Vol. 4, No. 3, 1974, pp. 311-314. doi:10.1016/0090-4295(74)90384-7
[13] W. T. Conner, G. W. Drach and W. C. Bucher, “Genitourinary Aspects of Disseminated Coccidioidomycosis,” Journal of Urology, Vol. 113, No. 1, 1975, pp. 82-88.
[14] E. A. Petersen, B. A. Friedman, E. D. Crowder and D. Rifkind, “Coccidoidouria: Clinical Significance,” Ann Internal Medicine, Vol. 85, No. 1, 1976, pp. 34-38. doi:10.7326/0003-4819-85-1-34
[15] K. T. Chen, “Coccidioidomycosis of the Epididymis” Journal of Urology, Vol. 130, No. 5, 1983, pp. 978-979.
[16] J. C. Liao and R. E. Reiter, “Coccidioidomycosis Presenting as Testicular Mass,” Journal of Urology, Vol. 166, No. 4, 2001, p. 1396. doi:10.1016/S0022-5347(05)65785-0
[17] A. Singer, “Coccidioidomycosis of the Epididymis and Testicle,” Infectious Urology, Vol. 15, No. 2, 2002, pp. 21-25.
[18] E. S. Halsey, M. S. Rasnake and D. R. Hospenthal, “Coccidioidomycosis of the Male Reproductive Tract,” Mycopathologia, Vol. 159, No. 2, 2005, pp. 199-204. doi:10.1007/s11046-004-6260-0
[19] M. R. Sohail, P. E. Andrews and J. E. Blair, “Coccidioidomycosis of the Male Genital Tract,” Journal of Urology, Vol. 173, No. 6, 2005, pp. 1978-1982. doi:10.1097/01.ju.0000158455.24193.12
[20] T. M. Dykes, A. B. Stone and E. D. Canby-Hagino, “Coccidioidomycosis of the Epididymis and Testis,” American Journal of Roentgenology, Vol. 184, No. 2, 2005, pp. 552-553. doi:10.2214/ajr. 184.2.01840552
[21] D. Ruggles, “Testicular Coccidioidomycosis,” Urologic Nursing, Vol. 28, No. 2, 2008, pp. 113-114.
[22] T. M. Chiller, J. N. Galgiani and D. A. Stevens, “Coccidioidomycosis,” Infectious Disease Clinics of North America, Vol. 17, No. 1, 2003, pp. 41-57. doi:10.1016/S0891-5520(02)00040-5

comments powered by Disqus

Copyright © 2019 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.