Successful Use of Sugammadex in a Myasthenic Patient Case Report

Abstract

The Myasthenia gravis (MG) is an autoimmune disease that affects neuromuscular transmission and leads to a large variation of sensibility on depolarizing and nondepolarizing neuromuscular blocking drugs. Sugammadex is a new drug with the capability to successfully revert the nondepolarizing neuromuscular blocking. This case report will show a patient with MG that was scheduled for thymectomy, with the objective to use sugammadex to reverse a rocuronium induced deep level of neuromuscular block and observing the safe use of sugammadex without complications.

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S. Rios, D. Gomes, M. De Miranda, C. La Cava and C. Bersot, "Successful Use of Sugammadex in a Myasthenic Patient Case Report," Open Journal of Anesthesiology, Vol. 3 No. 1, 2013, pp. 48-50. doi: 10.4236/ojanes.2013.31013.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] L. H. Phillips II, “The Epidemiology of Myasthenia Gravis,” Annals of the New York Academy of Sciences, Vol. 998, No. 1, 2006, pp. 407-412.
[2] K. Osserman and G. Genkins, “Studies in Myasthenia Gravis—Review of a 20-Year Eperience in over 1200 Patients,” Mount Sinai Journal of Medicine, Vol. 38, No. 6, 1971, pp. 497-537.
[3] S. J. A. Gold and N. J. N. Harper, “The Place of Sugammadex in Anaesthesia Practice,” Trends in Anaesthesia and Critical Care, Vol. 2, No. 1, 2012, pp. 4-9.
[4] F. X. Dillon, “Anesthesia Issues in the Perioperative Management of Myas-Thenia Gravis,” Seminars in Neurology, Vol. 24, No. 1, 2004, pp. 83-94. doi:10.1055/s-2004-829587
[5] X. Combes, L. Andriamidy, E. Dufresne, P. Suen, S. Sauvat, E. Scherrer, P. Feiss, J. Marty and P. Duvaldestin, “Comparison of Two Induction Regimens Using or Not Using Muscle Relaxant: Impact on Postoperative Upper Airway Discomfort,” British Journal of Anaesthesia, Vol. 99, No. 2, 2007, pp. 276-281. doi:10.1093/bja/aem147
[6] P. Duvaldestin, K. Kuizenga, V. Saldien, C. Claudius, F. Servin, J. Klein, B. Debaene and M. Heeringa, “A Randomized, Dose-Response Study of Sugam-Madex Given for the Reversal of Deep Rocuronium or Vecuronium Induced Neuromuscular Blockade under Sevourane Anesthesia,” Anesthesia and Analgesia, Vol. 110, No. 1, 2010, pp. 74-82. doi:10.1213/ANE.0b013e3181c3be3c
[7] A. Abrishami, J. Ho, J. Wong, L. Yin and F. Chung, Sugammadex, “A Selective Reversal Medication for Preventing Postoperative Residual Neuromuscular Blockade,” Anasthesia & Analgesia, Vol. 110, 2010, p. 1239.
[8] A. J. Aho, K. Kamata, A. Yli-Hankala, L. P. Lyytikinen, A. Kulkas and V. Jntti, “Elevated Bis and Entropy Values after Sugammadex or Neostig-Mine: An Electroencephalographic or Electromyographic Phenomenon?” Acta Anaesthesiologica Scandinavica, Vol. 56, No. 4, 2012, pp. 465-473. doi:10.1111/j.1399-6576.2011.02647.x

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