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Efficacy of rehabilitation program in addition to pharmacological treatment during 8 months in Parkinson patients

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DOI: 10.4236/apd.2012.12003    3,924 Downloads   7,233 Views   Citations


Objective: To compare 8-month effects ofmedical treatment plusrehabilitation on UPDRS scores ofparkinsonian patientswith that ofmedical treatment withoutrehabilitation.Design: Longtudinal randomized study. Participants:27 parkinsonian patients (69.50 ± 10.34 years). We divided our patient into two groups: control group (n = 9, received only medication therapy) and experiment- tal group (n = 18, received physiccal therapy and medication therapy). Intervention:The 8-month exercise interventions were twice-weekly 90-min sessions in group. UPDRS scales were measured before and after the interventions. Results: Two- factor ANOVA analyses revealed a significant main effect fromrehabilitation (p < 0.01) on UPDRS motor, ADL, and total, but not on UPDRS mental (p > 0.05). Post-hoc analysis shows that UPDRS motor increased in control group (+37%) meanwhile decreased in experimental group (–17%). UPDRS ADL increased significantly more in control group (+26%) than experimental group (+5%).UPDRS total increased in control group (+33%) meanwhile decreased in experimental group(–11%). Conclusions:The results of the study suggest that exercise interventions should be a necessary ongoing adjunct toparkinson’s diseasemedication.

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The authors declare no conflicts of interest.

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Calvo, J., Fernández, I., Alonso, J., Gallego, J. and Vallejo, N. (2012) Efficacy of rehabilitation program in addition to pharmacological treatment during 8 months in Parkinson patients. Advances in Parkinson's Disease, 1, 11-16. doi: 10.4236/apd.2012.12003.


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