Investigation of the Effect of Ambient Temperature and Geomagnetic Activity on the Vascular Parameters of Healthy Volunteers

Yury Gurfinkel, Tamara Breus, Tatyana Zenchenko, Vadim Ozheredov

Establishment of the Russian Academy of Sciences Space Research Institute (IKI RAS), Moscow, Russia.

DOI: 10.4236/ojbiphy.2012.22007                

Abstract

Aim of this paper is to reveal whether the geomagnetic activity (GMA) and meteorological factors (MFs) affect vascular parameters of healthy volunteers. As a trial study we used new device “Tonocard,” and new vascular parameters for study—a pulse wave velocity (PWV) and an endothelial function (EnF) in addition to blood pressure measurements. These parameters never investigated before in such aspects. As far as novelty of device itself and investigated parameters we limited ourselves by monitoring only four healthy volunteers (without cardiovascular pathology). To analyze the sensitivity of their aforementioned medical indices to GMA and MFs two independent mathematical approaches were used, one of whom is based on traditional methods of mathematical statistics and the other on the theory of pattern recognition Dependence of physiological characteristics on the atmospheric temperature, revealed by both applied mathematical approaches, showed complex non-linear character of biological replies: the reaction has a different form in different temperature ranges and is manifested in the form of synchronization of slow variations of physiological and atmospheric parameters (trends) with a period of several days, while the daily variations were virtually independent. The systolic blood pressure (SBP), PWV and a difference between two specially selected values of PWV (DPWV) are approximately equally depending on atmospheric temperature, which accounts for an average of 26% to 28% of their variations. Sensitivity to the GMA for this test was found only for PWV.

Keywords

Vascular Parameters; Geomagnetic Disturbances; Meteorological Factors

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1]	T. Breus, G. Cornelissen, F. Halberg and A. E. Levitin, “Temporal Associations of Life with Solar and Geophysical Activity,” Annales Geophysicae, Vol. 13, 1995, pp. 1211-1222. doi:10.1007/s00585-995-1211-8
[2]	E. Stoupel, J. Petrauskiene, E. Abramson, R. Kaledie, P. Izrailevich and J. Sulkes, “Relationship between Death from Stroke and Ischemic Heart Disease—Environmental Implications,” Journal of Basic and Clinical Physiology and Pharmacology, Vol. 10, No. 2, 1999, pp.135-139. doi:10.1515/JBCPP.1999.10.2.135
[3]	S. Palmer, M. Rycroft and M. Cermack, “Solar and Geomagnetic Activity, Extremely Low Frequency Magnetic and Electric Fields and Human Health at the Earth’s Surface,” Surveys in Geophysics, Vol. 27, 2006, p. 557. doi:10.1007/s10712-006-9010-7
[4]	V. A. Ozheredov, T. K. Breus, Yu. I. Gurfinkel, D. A. Revich and T. A. Mitrofanova, “Influence of Some Weather Factors and Geomagnetic Activity on the Development of Severe Cardiological Pathologies,” Biophysics, Vol. 55, No. 1, 2010, pp. 110-119. doi:10.1134/S0006350910010185
[5]	T. A. Zenchenko, L. V. Poskotinova, A. G. Rekhtina and R. M. Zaslavskaya, “Relation between Microcirculation Parameters and Pc3 Geomagnetic Pulsations,” Biophysics, Vol. 55, No. 4, 2010, pp. 646-651. doi:10.1134/S000635091004024X
[6]	B. A. Revich and D. A. Shaposhnikov, “Climate Conditions, Quality of Atmospheric Air and Mortality of Population in Moscow in 2000-2006,” In: B. A. Revich, Ed., Climate, Quality of Atmospheric Air and Health of Muscovites, Adamant, Moscow, 2006, pp. 102-140 (in Russian).
[7]	J. Schwartz, M. Jonathan and A. Jonathan, “Hospital Admissions for Heart Disease: The Effects of Temperature and Humidity,” Epidemiology, Vol. 15, No. 6, 2004, p. 755. doi:10.1097/01.ede.0000134875.15919.0f
[8]	P. Michelozzi, G. Accetta, M. De Sario, D. D’Ippoliti, C. Marino, M. Baccini, A. Biggeri, H. Ross Anderson, K. Katsouyanni, F. Ballester, L. Bisanti, E. Cadum, B. Forsberg, F. Forastiere, P. G. Goodman, A. Hojs, U. Kirchmayer, S. Medina, A. Paldy, C. Schindler, J. Sunyer, C. A. Perucci and on Behalf of the PHEWE Collaborative Group, “High Temperature and Hospitalizations for Cardiovascular and Respiratory Causes in 12 European Cities,” American Journal of Respiratory and Critical Care Medicine, Vol. 179, No
[9]	T. K. Breus, R. M. Baevsky, G. A. Nikulina and A. G. Chernikova, “Geomagnetic Activity Effects on Humans in Nonstationary Extremely Conditions and Comparison with Laboratory Observations,” Biophysics, Vol. 43, No. 5, 1998, pp. 767-775.
[10]	T. K. Breus, R. M. Baevskii, I. I. Funtova and A. G. Chernikova, “Effect of Geomagnetic Field Disturbances on the Adaptive Stress Reaction of Cosmonauts,” Cosmic Research, Vol. 46, No. 4, 2008, pp. 367-372. doi:10.1134/S0010952508040138
[11]	G. Cornelissen, F. Halberg, T. K. Breus, E. V. Syutkina, R. M. Baevskii, A. Weydahl, Y. Watanabe, K. Otsuka, J. Siegelova, B. Fiser and E. E. Bakken, “Non-Photic Solar Associations of Heart Rate Variability and Myocardial Infarction,” Journal of Atmospheric and Solar-Terrestrial Physics, Vol. 64, 2002, pp. 707-728.
[12]	T. K. Breus, V. A. Ozheredov, E. V. Syuitkina and A. N Rogoza, “Some Aspects of the Biological Effects of Space Weather,” Journal of Atmospheric and Solar Terrestrial Physics, Vol. 70, 2008, pp. 436-441.
[13]	Yu. I. Gurfinkel, V. V. Lubimov, V. N. Oraevskii, L. L. Parfemova and A. S. Yuriev, “Effect of Geomagnetic Disturbances on Capillary Blood Flow in Patients Suffering from Ischemic Heart Disease,” Biophysics, Vol. 40, No. 4, 1995, pp. 777-783.
[14]	J. N. Cohn, “Arterial Stiffness, Vascular Disease, and Risk of Cardiovascular Events,” Circulation, Vol. 113, 2006, pp. 601-603. doi:10.1161/CIRCULATIONAHA.105.600866
[15]	F. U. Mattace-Raso, T. J. van der Cammen, A. Hofman, N. M. van Popele, M. L. Bos, M. A. Schalekamp, R. Asmar, R. S. Reneman, A. P. Hoeks, M. M. Breteler and J. C. Witteman, “Arterial Stiffness and Risk of Coronary Heart Disease and Stroke: The Rotterdam Study,” Circulation, Vol. 113, 2006, pp. 657-663. doi:10.1161/CIRCULATIONAHA.105.555235
[16]	T. Willum Hansen, J. A. Staessen, C. Torp-Pedersen, S. Rasmussen, L. Thijs, H. Ibsen and J. Jeppesen, “Prognostic Value of Aortic Pulse Wave Velocity as Index of Arterial Stiffness in the General Population,” Circulation, Vol. 113, 2006, pp. 664-670. doi:10.1161/CIRCULATIONAHA.105.579342
[17]	G. E. McVeigh, P. B. Allen, D. R. Morgan, C. G. Hanratty and B. Silke, “Nitric Oxide Modulation of Blood Vessel Tone Identified by Arterial Waveform Analysis,” Clinical Science, Vol. 100, 2001, pp. 387-393. doi:10.1042/CS20000227
[18]	Yu. I. Gurfinkel, N. V. Katse, L. M. Parfenova, I. Yu. Ivanova and V. A. Orlov, “Comparative Study of Pulse Wave Velocity and Endothelial Function at Healthy Subjects and at Patients with a Cardiovascular Pathology,” Russian Journal of Cardiology, Vol. 76, No. 2, 2009, pp. 38-43.
[19]	V. A. Ozheredov, “Investigation of Space and Terrestrial Weather Effects on Human Organism on the Basis of Optimization Algorithms,” Ph.D. Dissertation (IKI RAS), Central Governmental Library in Moscow, 2010, 193 p.
[20]	A. Yu. Loskutov, J. L. Kotlyakov, I. A. Istomin and D. I. Zhuravlev, “Problems of Nonlinear Dynamics III: Local Methods of Time Series Forecast,” Vestnik of Moscow State University, Physics and Astrophysics Series, No. 6, 2002, pp. 3-21.
[21]	J. McNames, J. A. K. Suykens and J. Vandewalle, “Winning Entry of the K. U. Leuven, Time Series Prediction Competition,” International Journal of Bifurcation and Chaos, Vol. 9, No. 8, 1999, pp. 1485-1500. doi:10.1142/S0218127499001048
[22]	E. L. Leman, “Checking of Statistical Hypothesis,” NAUKA, 1978, 408 p.
[23]	T. A. Zenchenko, T. K. Breus, E. V. Tsagareishvili, J. V. Oschepkova and A. N. Rogoza, “Typology of Reactions on the Space and Terrestrial Weather Variations for Patients Suffering From Hypertension and for Healthy People,” In: M. Jordanova and F. Lievens, Eds., Global Telemedicine and eHealth Updates: Knowledge Resources, Medtech Pub Co, New Glouchester, Vol. 2, 2009, pp. 49-410.
[24]	T. A. Zenchenko, “Method of Analysis of Time Series Data for the Complex Estimation of Meteoand MagnetoSensitivity of Human Organism,” Human Ecology (in Russian), No. 2, 2010, pp. 3-11.