Author(s)

Giuliana Carpentieri-Pipolo¹, Marcelo de Lima Oliveira², Fernando Mendes Paschoal Junior², Edson Bor-Seng-Shu²

¹Brazilian Ministry of Health, São Paulo, Brazil.
²Department of Neurosurgery, Hospital das Clínicas, School of Medicine of University of São Paulo, São Paulo, Brazil.

Sickle-cell disease (SCD) is the most common cause of ischemic stroke in children and it happens in about 11% of patients between the age of 2 and 20 years old. About 7% of the world population is affected by hemoglobin disorders, mostly sickle cell anemia. SCD has a high prevalence in the population of African offspring and it is a public health problem in Brazil that affects more than 30,000 million people. Prevention of primary stroke might be feasible with a way to identify children at greatest risk. Transcranial Doppler Ultrasonography (TCD) to SCD patients can be a valuable service that results in a significant decrease of first stroke rates. In this work, we present a review about TCD as an effective strategy to detect children with SCD who are at risk for stroke.

Transcranial Doppler, Sickle Cell Disease, Stroke in Children, Cerebrovascular Disease

Carpentieri-Pipolo, G. , de Lima Oliveira, M. , Paschoal Junior, F. and Bor-Seng-Shu, E. (2019) Transcranial Doppler Ultrasonography to Prevent Cerebrovascular Accident in Children with Sickle-Cell Disease. Neuroscience and Medicine, 10, 162-173. doi: 10.4236/nm.2019.102011.