Analysis of Autonomic, Respiratory and Motor Function of Infants in Pre- and Post-Liver Transplantation

HTML  XML Download Download as PDF (Size: 2578KB)  PP. 1384-1391  
DOI: 10.4236/ijcm.2014.521176    4,155 Downloads   4,940 Views  

ABSTRACT

Purpose: Children with liver impairment are likely to develop changes in autonomic nervous function and delay in motor development. The assessment and identification of these dysfunctions may allow an appropriate physiotherapeutic care. Method: Cross sectional study of 18 infants, 11 controls and 7 infants (post-liver transplantation) with an average age of 10 ± 4.5 months, was evaluated in pre- and post-liver transplant. All infants underwent to assessments of motor skills, body composition, chest and abdominal motion, and cardiac autonomic modulation was measured by heart rate variability. Results: Motor delay and malnutrition were found in all infants. The gravity index (PELD)—pediatric end-stage liver disease—showed a negative correlation with the Alberta Infant Motor Scale (r = 0.83, p = 0.01). In addition, reduced parasympathetic modulation was demonstrated by the rMSSD, SD1 and ApEn, pre- and post-transplant. Conclusion: Infants with liver disease, even after transplantation, have delay in motor development, as well as changes in their nutritional and autonomic dysfunction.

Share and Cite:

Rolim, D. , Gomes, É. , Queiroga, A. , Roche, J. , Borghi-Silva, A. and Sampaio, L. (2014) Analysis of Autonomic, Respiratory and Motor Function of Infants in Pre- and Post-Liver Transplantation. International Journal of Clinical Medicine, 5, 1384-1391. doi: 10.4236/ijcm.2014.521176.

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.