Case Report on Acute Psychosis Due to Anti-NMDAR Encephalitis - Open Journal of Internal Medicine

OJIM > Vol.4 No.1, March 2014

Case Report on Acute Psychosis Due to Anti-NMDAR Encephalitis ()

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DOI: 10.4236/ojim.2014.41005 3,151 Downloads 4,794 Views

Author(s)

Shabana Ahamed, Harin Karunajeewa

Affiliation(s)

Western Health, Melbourne, Australia.

ABSTRACT

A 32-year-old female with depression on treatment, was presented with acute psychosis, behavioural symptoms, autonomic instability and a prodromal illness. This occurred on a background of a strong family history of schizophrenia. Despite escalating doses of anti-psychotics, she failed to improve. Her CSF showed a lymphocytic pleocytosis and confirmed the presence of anti-NMDAR antibodies. Following treatment with immunotherapy and excision of her underlying ovarian tumour, she showed a dramatic and seemingly full recovery of her psychotic symptoms. She was weaned off all medications with no residual symptoms. Clinician awareness is important to treat this uncommon but potentially reversible condition.

KEYWORDS

Psychosis; Ovarian Teratoma; Encephalitis

Share and Cite:

Ahamed, S. and Karunajeewa, H. (2014) Case Report on Acute Psychosis Due to Anti-NMDAR Encephalitis. Open Journal of Internal Medicine, 4, 28-32. doi: 10.4236/ojim.2014.41005.

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