The history of medicine and surgery is a rich source of interesting stories of genius and brave people who paved the way ahead of mankind towards the current status of medical and surgical practice. One has to admire the enthusiasms and courage of such people to whom millions of patients ought to be grateful. This paper reports the inspiring stories of 3 heart surgeons (Werner Forssmann, Dr. Lillehei and Dr. Michael E. DeBakey) and highlights their outstanding contributions to the modern cardiac surgery. It reminds the people to remember these three pioneers forever and encourages people working in this field to seek innovation.