Studies on Dissolution Behaviour of Nanoparticulate Curcumin Formulation

HTML  XML Download Download as PDF (Size: 322KB)  PP. 51-59  
DOI: 10.4236/anp.2013.21010    12,662 Downloads   22,057 Views  Citations
Author(s)

ABSTRACT

Curcumin is the main biologically active phytochemical compound of turmeric that has been widely used by ancient cultures throughout Asia. However the dissolution rate limited absorption and pre-absorption degradation limits its use as a potential therapeutic. In this study an attempt has been made to overcome the above limitations by curcumin delivery through nanotechnology. Nanocurcumin solid dosage formulations were prepared and studied for its dissolution behaviour. Considerable improvement in the dissolution behavior was observed in the drug nanocrystal-loaded solid dosage forms. This is expected to enhance the bioavailability of poorly soluble medicinal herbs such as turmeric in the body.

Share and Cite:

Ravichandran, R. (2013) Studies on Dissolution Behaviour of Nanoparticulate Curcumin Formulation. Advances in Nanoparticles, 2, 51-59. doi: 10.4236/anp.2013.21010.

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.