Paediatric amitriptyline overdose

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DOI: 10.4236/ojped.2012.22028    6,843 Downloads   10,507 Views  Citations

ABSTRACT

We report a near fatal case of paediatric amitriptyline overdose including a series of ECGs demonstrating the effects of sodium bicarbonate therapy on cardio-toxicity. We briefly discuss the role of sodium to counteract the sodium channel blockade of tricyclic antidepressants and discuss the possible utility of lipid emulsion therapy in such cases.

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Doherty, S. , Cave, G. and Harvey, M. (2012) Paediatric amitriptyline overdose. Open Journal of Pediatrics, 2, 170-174. doi: 10.4236/ojped.2012.22028.

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