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Crystal Type Iof Azilsartan Polymorphs: Preparation and Analysis

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DOI: 10.4236/jcpt.2016.61001    3,406 Downloads   3,951 Views Citations


Azilsartan (2-ethoxy-1-([2’-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl)-1H-benzimidazole-7-carboxylic acid) is a new angiotensin II receptor antagonist used in the treatment of hypertension. This paper describes the preparation of type I crystal and its single crystal diffraction data, the comparison of the powder diffraction data for both type I and II crystals as well as their stability and solubility in methanol.

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Ge, Y. , Li, T. and Cheng, J. (2016) Crystal Type Iof Azilsartan Polymorphs: Preparation and Analysis. Journal of Crystallization Process and Technology, 6, 1-10. doi: 10.4236/jcpt.2016.61001.

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