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Evaluation of a Plasma hCG Method for Point of Care Testing with the Aim of Shortening Test-Turnaround-Times

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DOI: 10.4236/ojog.2015.56049    2,898 Downloads   3,275 Views   Citations


Objective: To examine the correlation between plasma hCG results obtained with the new i-STAT® hCG point of care test with those concomitantly obtained from the central hospital laboratory utilizing the same patient samples. Methods: Prospective cross-sectional laboratory test evaluation. We compared plasma hCG results obtained with the i-STAT® hCG test (Abbott Point of Care, Princeton, NJ, USA) with Architect Ci8200 (Abbott Laboratories, Abbott Park, IL, USA). We also calculated the total coefficient of variation (CV) for the i-STAT® method. Results: The two methods showed a good linear correlation (R2 = 0.994; slope 1.03) and CV for the i-STAT® method was 2.1% - 5.2%. Conclusion: We suggest that the i-STAT® hCG blood assay could be used as a complement to urine hCG assays in clinical situations when rapid test results are needed and urine is not available.

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The authors declare no conflicts of interest.

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Wikström, A. , Hagmar, M. , Ronquist, G. and Larsson, A. (2015) Evaluation of a Plasma hCG Method for Point of Care Testing with the Aim of Shortening Test-Turnaround-Times. Open Journal of Obstetrics and Gynecology, 5, 341-343. doi: 10.4236/ojog.2015.56049.


[1] Vaitukaitis, J.L. (2004) Development of the Home Pregnancy Test. Annals of the New York Academy of Sciences, 1038, 220-222.
[2] Cacciatore, B., Stenman, U.H. and Ylostalo, P. (1990) Diagnosis of Ectopic Pregnancy by Vaginal Ultrasonography in Combination with a Discriminatory Serum hCG Level of 1000 IU/l (IRP). British Journal of Obstetrics and Gynaecology, 97, 904-908.
[3] Gronowski, A.M., Powers, M., Stenman, U.H., Ashby, L. and Scott, M.G. (2009) False-Negative Results from Point-of-Care Qualitative Human Chorionic Gonadotropin (hCG) Devices Caused by Excess hCGbeta Core Fragment Vary with Device Lot Number. Clinical Chemistry, 55, 1885-1886.

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